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Título:
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Evaluation of a New Immunochromatographic Test Using Recombinant Antigen B8/1 for Diagnosis of Cystic Echinococcosis
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Autores:
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Santivanez, Saul J. ;
Rodriguez, Mary L. ;
Rodriguez, Silvia ;
Sako, Yashuito ;
Nkouawa, Agathe ;
Kobayashi, Yukuharu ;
Sotomayor, Alfredo L. ;
Peralta, Julio E. ;
Valcarcel, Maria ;
Gonzalez, Armando E. ;
Garcia, Hector H. ;
Ito, Akira
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Tipo de documento:
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texto impreso
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Editorial:
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American Society for Microbiology, 2019-02-06T14:52:38Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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Diagnosis of cystic echinococcosis (CE) is based on the identification of the cyst(s) by imaging, using immunodiagnostic tests mainly as complementary tools in clinical settings. Among the antigens used for immunodiagnosis, previous studies described a good performance of the recombinant antigen B8/1 (rAgB) in an enzyme-linked immunosorbent assay (ELISA) format; however, in remote parts of areas where the disease is endemic, the implementation of an ELISA is difficult, so a more simple, rapid, and reliable method such as the immunochromatographic test (ICT) is required. In this study, using a set of 50 serum samples from patients with surgically confirmed CE, we compared the performance of an ICT and that of an ELISA using the rAgB. The overall sensitivities of ICT and ELISA were not statistically different (78% versus 72%; P = 0.36). The overall agreement between both tests was moderate (kappa = 0.41; P
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En línea:
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http://doi.org/10.1128/JCM.02157-15
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