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Título:
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Nitrofuran resistance in Salmonella enterica isolated from meat for human consumption
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Autores:
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Martínez-Puchol, S. ;
Pons, M.J. ;
Ruiz-Roldán, L. ;
Laureano-Adame, L. ;
Corujo, A. ;
Ochoa, T.J. ;
Ruiz, J.
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Tipo de documento:
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texto impreso
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Editorial:
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Instituto Nacional de Salud, 2020-12-14T16:06:32Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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The mechanisms of resistance to nitrofurans from 18 meat samples with Salmonella enterica (chicken: 15; beef: 2; pork: 1) collected in Lima (Peru) were analyzed. The isolates were serotyped and the susceptibility levels to furazolidone and nitrofurantoin [with and without the efflux pump inhibitor Phenyl-Arginine-?-naphthylamide (PA?N)], the presence of mutations in the snrA and cnr genes and the transferability of resistance by conjugation were established. Fifteen samples with S. infantis (13 from chicken samples), 2 with S. enteritidis and 1 with S. anatum were identified. All isolates except the S. anatum were resistant to both nitrofurans showing MICs (minimum inhibitory concentration) of furazolidone and nitrofurantoin of 32-64 ?g/mL and 128-256 ?g/mL, respectively. The addition of PAßN had no effect on the MIC levels. All nitrofuran-resistant isolates showed amino acid codon alterations at both snrA and cnr (S. infantis: snrA STOP-151; cnr STOP-137; S. enteritidis: snrA STOP-180; cnr STOP-179). No transferable mechanisms of nitrofuran resistance were detected. © 2020, Instituto Nacional de Salud. All rights reserved.
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En línea:
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http://repositorio.upch.edu.pe/handle/upch/8735
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