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González Álvaro, I. ; Ortiz, A. Mª. ; Valiño Seoane, Iria ; García Vicuña, Rosario ; Martínez, C. ; Gomáriz, Rosa P. | Bentham Science Publishers | 2015The heterogeneous nature of rheumatoid arthritis (RA) complicates early recognition and treatment. In recent years, a growing body of evidence has demonstrated that intervention during the window of opportunity can improve the response to treatm[...]texto impreso
Invasive Candidiasis (IC) poses a major public health problem worldwide. Despite the introduction of new antifungal agents and changes in clinical practices, its morbidity and mortality rates and healthcare costs remain persistently high. This i[...]texto impreso
Doadrio Villarejo, Antonio Luis ; Salinas Sánchez, Antonio J. ; Sánchez-Montero, José M. ; Vallet Regí, María | Bentham Science Publishers | 2015The state-of-the-art in the investigation of drugs release from Silica-based ordered Mesoporous Materials (SMMs) is reviewed. First, the SMM systems used like host matrixes are described. Then, the model drugs studied until now, including their [...]texto impreso
Alarcón, Borja ; Armas, Roberto de ; Vicente Córdoba, Carlos ; Legaz González, María Estrella | Bentham Science Publishers | 2019Aims and Objectives: This study aimed to characterize a coniferyl alcohol dehydrogenase from sugarcane stalks. Also, the purification of CAD from sugarcane stalks was also carried out to study kinetic properties and substrate specificity. Backg[...]texto impreso
T cell immune responses are driven by the recognition of peptide antigens (T cell epitopes) that are bound to major histocompatibility complex (MHC) molecules. T cell epitope immunogenicity is thus contingent on several events, including appropr[...]texto impreso
Cabanac, Michel ; Ramirez, J. Martin ; Millana Cuevas, Luis Clemente ; Toldos Romero, María Paz ; Bonniot-Cabanac, Marie-Claude | Bentham Science Publishers | 2008To a large degree, humans use pleasure (hedonicity) maximization to guide decision making, thereby optimizing their behaviour, as shown by research on either sensory or purely mental pleasure (e.g., pleasure from video-game playing or mathematic[...]