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Título:
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Population Screening for Urine Antigens to Detect Asymptomatic Subarachnoid Neurocysticercosis: A Pilot Study in Northern Peru
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Autores:
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McCleery, E. ;
Allen, S.E. ;
Moyano, L.M. ;
Gamboa, R. ;
Vilchez, P. ;
Muro, C. ;
Castillo, Y. ;
Dorny, P. ;
Garcia, H.H. ;
O’Neal, S.E.
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Tipo de documento:
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texto impreso
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Editorial:
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American Society of Tropical Medicine and Hygiene, 2020-12-14T16:06:33Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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Subarachnoid neurocysticercosis (SANCC) is a severe and progressive brain infection with Taenia solium. We performed a pilot study of noninvasive screening for SANCC in two endemic villages in northern Peru using a urine antigen screen followed by brain magnetic resonance imaging for participants with elevated levels of antigen. Among the 978 participants screened, we identified eight individuals with SANCC, many of whom were asymptomatic. This represents a minimum prevalence of 0.8% of SANCC, a level higher than expected based on prior studies, and a positive predictive value of 62% for our novel urine screening test. Future studies should confirm whether early detection and management improve clinical outcomes. © 2020 American Society of Tropical Medicine and Hygiene. All rights reserved.
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En línea:
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http://repositorio.upch.edu.pe/handle/upch/8737
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