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Título:
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Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control
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Autores:
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Oriol-Tordera, B. ;
Berdasco, M. ;
Llano, A. ;
Mothe, B. ;
Gálvez, C. ;
Martinez-Picado, J. ;
Carrillo, J. ;
Blanco, J. ;
Duran-Castells, C. ;
Ganoza, C. ;
Sánchez, J. ;
Clotet, B. ;
Calle, M.L. ;
Sánchez-Pla, A. ;
Esteller, M. ;
Brander, C. ;
Ruiz-Riol, M.
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Tipo de documento:
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texto impreso
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Editorial:
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Public Library of Science, 2020-12-14T16:10:02Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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GWAS, immune analyses and biomarker screenings have identified host factors associated with in vivo HIV-1 control. However, there is a gap in the knowledge about the mechanisms that regulate the expression of such host factors. Here, we aimed to assess DNA methylation impact on host genome in natural HIV-1 control. To this end, whole DNA methylome in 70 untreated HIV-1 infected individuals with either high (>50,000 HIV-1-RNA copies/ml, n = 29) or low (
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En línea:
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http://repositorio.upch.edu.pe/handle/upch/8753
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