|
Título:
|
Pneumocystis primary infection in infancy: Additional French data and review of the literature
|
|
Autores:
|
Nevez, Gilles ;
Guillaud-Saumur, Thibaud ;
Cros, Pierrick ;
Papon, Nicolas ;
Vallet, Sophie ;
Quinio, Dorothee ;
Minoui-Tran, Adissa ;
Pilorge, Lea ;
de Parscau, Loic ;
Sizun, Jacques ;
Ochoa, Theresa J. ;
Bustamante, Beatriz ;
Ponce, Carolina ;
Vargas, Sergio L. ;
Le Gal, Solene
|
|
Tipo de documento:
|
texto impreso
|
|
Editorial:
|
Oxford University Press, 2019-07-04T17:00:20Z
|
|
Nota general:
|
info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
|
|
Idiomas:
|
Inglés
|
|
Palabras clave:
|
Editados por otras instituciones
,
Artículos
,
Artículos en revistas indizadas
|
|
Resumen:
|
Data on features of Pneumocystis primary infection in infancy are still fragmented. To study Pneumocystis primary infection, 192 infants who were monitored for acute pulmonary disease or fever over a 40-month period were retrospectively investigated. P. jirovecii detection on archival nasopharyngeal aspirates was performed using a qPCR assay. Factors associated with P. jirovecii were assessed using univariate and multivariate analyses. P. jirovecii genotypes in infants and a control group of adults contemporaneously diagnosed with Pneumocystis pneumonia were identified using unilocus, bilocus, and multilocus sequence typing (MLST). P. jirovecii was detected in 35 infants (18.2%). The univariate analysis pointed out four factors: viral infection (P = .035, OR [IC 95], 2.2 [1.1-4.7]), lower respiratory tract infection (P = .032, OR [IC 95], 2.5 [1.1-5.9]), absence of hospital discharge after birth (P = .003, OR (IC 95), 0.1 (0.02-0.5]), and the 63-189-day group (P
|
|
En línea:
|
http://doi.org/10.1093/mmy/myz040
|
