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Título:
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Exercise-induced increase in hemoglobin concentration at intermediate and high altitudes in Andeans, Tibetans and Han Chinese
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Autores:
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Gu, Wanjun ;
Wuren, Tana ;
Xu, Ian ;
Qin, Ga ;
Yan, Ma ;
Wei, Guan ;
Wagner, Harrieth ;
Macarlupu, Jose ;
Vicardo, Gustavo ;
Anza, Cecilia ;
Villafuerte, Francisco ;
Ge, Ri-Li ;
Wagner, Peter ;
Simonson, Tatum
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Tipo de documento:
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texto impreso
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Editorial:
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Federation of American Society of Experimental Biology, 2020-07-14T00:01:12Z
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Nota general:
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info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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An acute increase in hemoglobin concentration ([Hb]) up to 1.6 g/dL has been previously reported under the condition of exercise-induced hypoxemia in sea level individuals with COPD (Schagatay et.al 2015). Changes in [Hb] have been attributed to splenic contraction. To determine whether, and to what extent, [Hb] changes acutely in response to exercise in long-term residents at high altitude, we compared hemoglobin concentration at rest and during exercise in male Andean (n = 14; 4330 m) and Tibetan (n = 21; 4200 m) native highlanders, whose ancestors have resided for hundreds of generations at altitude, as well as Han Chinese (n = 9; 4200 m) high-altitude residents. In the latter two populations, we further examined male (Tibetan n = 10; Han n = 8) and female (Tibetan n = 9; Han n = 10) individuals both at a resident altitude of 2200 m and simulated altitude of 4200 m in a hypobaric chamber. We measured [Hb] at rest ([Hb]r), and peak exercise ([Hb]p), as well as blood oxygen saturation (SaO2), cardiac output (QT), VO2 and body mass index (BMI) and compared [Hb]p - [Hb]r, denoted as ?[Hb], for male Andeans at 4300 m, male Tibetans and Han Chinese resident at 4200 m, male and female Tibetans and Han Chinese resident at 2200 m and under simulated 4200 m. [Hb] significantly increased with exercise in all groups (P
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En línea:
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http://repositorio.upch.edu.pe/handle/upch/8299
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