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Título:
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Sedation practices and clinical outcomes in mechanically ventilated patients in a prospective multicenter cohort
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Autores:
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Aragon, Romina E. ;
Proaño, Alvaro ;
Mongilardi, Nicole ;
de Ferrari, Aldo ;
Herrera, Phabiola ;
Roldan, Rollin ;
Paz, Enrique ;
Jaymez, Amador A. ;
Chirinos, Eduardo ;
Portugal, Jose ;
Quispe, Rocio ;
Brower, Roy G. ;
Checkley, William
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Tipo de documento:
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texto impreso
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Editorial:
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BMC, 2019-07-04T17:00:23Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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OBJECTIVES: We sought to study the association between sedation status, medications (benzodiazepines, opioids, and antipsychotics), and clinical outcomes in a resource-limited setting. DESIGN: A longitudinal study of critically ill participants on mechanical ventilation. SETTING: Five intensive care units (ICUs) in four public hospitals in Lima, Peru. PATIENTS: One thousand six hundred fifty-seven critically ill participants were assessed daily for sedation status during 28 days and vital status by day 90. RESULTS: After excluding data of participants without a Richmond Agitation Sedation Scale score and without sedation, we followed 1338 (81%) participants longitudinally for 18,645 ICU days. Deep sedation was present in 98% of participants at some point of the study and in 12,942 ICU days. Deep sedation was associated with higher mortality (interquartile odds ratio (OR) = 5.42, 4.23-6.95; p
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En línea:
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http://doi.org/10.1186/s13054-019-2394-9
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