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Título:
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Risk Factors Associated with Incident Syphilis in a Cohort of High-Risk Men in Peru
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Autores:
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Park, Hayoung ;
Konda, Kelika-A. ;
Roberts, Chelsea-P. ;
Maguina, Jorge-L. ;
Leon, Segundo-R. ;
Clark, Jesse-L. ;
Coates, Thomas-J. ;
Caceres, Carlos-F. ;
Klausner, Jeffrey-D.
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Tipo de documento:
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texto impreso
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Editorial:
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Public Library of Science, 2019-02-06T14:45:57Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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BACKGROUND: Syphilis is concentrated among high-risk groups, but the epidemiology of syphilis reinfection is poorly understood. We characterized factors associated with syphilis incidence, including reinfection, in a high-risk cohort in Peru. METHODS: Participants in the NIMH CPOL trial were assessed at baseline and 2 annual visits with HIV/STI testing and behavioral surveys. Participants diagnosed with syphilis also attended 4- and 9-month visits. All participants underwent syphilis testing with RPR screening and TPPA confirmation. Antibiotic treatment was provided according to CDC guidelines. Reinfection was defined as a 4-fold titer increase or recurrence of seroreactivity after successful treatment with subsequent negative RPR titers. The longitudinal analysis used a Possion generalized estimating equations model with backward selection of variables in the final model (criteria P
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En línea:
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http://doi.org/10.1371/journal.pone.0162156
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