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Título:
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Hipertensión portal no cirrótica por didanosina. Un caso infrecuente
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Autores:
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Gamero, Maria T. ;
Gallardo, Maria Susana ;
Aguilar, Victor ;
Bravo, Eduar ;
Guevara, Julissa ;
Mejia, Fernando
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Tipo de documento:
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texto impreso
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Editorial:
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Sociedad de Gastroenterología del Perú, 2019-01-25T16:59:38Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Español
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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Liver involvement is usually seen in patients infected with the human immunodeficiency virus (HIV), especially in patients coinfected with hepatitis B or C, in alcohol abuse, etc. However, there is a group of patients who develop liver involvement and portal hypertension of unspecified cause. Non-cirrhotic portal hypertension (NCPH) is a liver disorder recently described, but potentially serious. It has been reported in HIV-infected patients with highly active antiretroviral therapy (HAART), specifically didanosine (DDI). The pathophysiology involves the infectious agent (HIV) and its treatment (HAART), since both generate a pre-hepatic portal venulopathy. Similarly, HIV infection produces a prothrombotic state by protein S deficiency leading to the obliteration of small hepatic venules. It has been postulated that DDI as a cofactor in the pathogenesis of NCPH. All this leads that many of the liver biopsies show nodular regenerative hyperplasia. We present the case of a
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En línea:
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http://www.revistagastroperu.com/index.php/rgp/article/view/85
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