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Título:
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pic gene of enteroaggregative Escherichia coli and its association with diarrhea in Peruvian children
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Autores:
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Durand, David ;
Contreras, Carmen A. ;
Mosquito, Susan ;
Ruiz, Joaquim ;
Cleary, Thomas G. ;
Ochoa, Theresa J.
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Tipo de documento:
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texto impreso
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Editorial:
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Taylor & Francis, 2019-02-22T14:54:28Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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Enteroaggregative Escherichia coli (EAEC) causes acute and persistent diarrhea among children, HIV-infected patients, and travelers to developing countries. We have searched for 18 genes-encoding virulence factors associated with aggregative adherence, dispersion, biofilm, toxins, serine protease autotransporters of Enterobacteriaceae (SPATEs) and siderophores, analyzed in 172 well-characterized EAEC strains (aggR(+)) isolated from stool samples of 97 children with diarrhea and 75 healthy controls from a passive surveillance diarrhea cohort study in Peru. Eighty-one different genetic profiles were identified, 37 were found only associated with diarrhea and 25 with control samples. The most frequent genetic profile was aggC(+)aatA(+)aap(+)shf(+)fyuA(+), present in 19 strains, including diarrhea and controls. The profile set1A(+)set1B(+)pic(+) was associated with diarrhea (P = 7 days) (P
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En línea:
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http://doi.org/10.1093/femspd/ftw054
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