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Título:
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Lack of evidence for Toxocara infection in Italian myelitis patients
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Autores:
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Nicoletti, Alessandra ;
Garcia, Hector H. ;
Cicero, Calogero Edoardo ;
Portaro, Giacomo ;
Giuliano, Loretta ;
Patti, Francesco ;
Sofia, Vito ;
Noh, John ;
Handali, Sukwan ;
Zappia, Mario
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Tipo de documento:
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texto impreso
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Editorial:
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Springer Verlag, 2019-08-08T15:23:47Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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Acute myelitis is a common neurological manifestation due to different causes, but in about 15-30% of cases its etiology remains unknown (idiopathic myelitis). Myelitis represents the most common manifestation of neurotoxocariasis, the infection of the human nervous system by larvae of the nematode Toxocara spp.; however, despite the high seroprevalence worldwide, its contribution to the burden of disease has not been assessed. We evaluated the presence of antibodies against Toxocara spp. in cerebrospinal fluid (CSF) from a sample of 28 patients with a diagnosis of idiopathic myelitis (N = 20) or encephalomyelitis (N = 8) who attended the Neurological Unit of the University Hospital of Catania, Sicily. Antibodies against Toxocara spp. were measured using a multiplex bead-based assay and Toxocara immunoblot using Toxocara canis excretory secretory antigens. All samples tested negative for the presence of anti-T. canis IgG antibodies. In this series, we found no evidence of a contribution of neurotoxocariasis to the burden of myelitis.
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En línea:
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http://doi.org/10.1007/s10072-019-04017-9
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