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Título:
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Lack of an Association Between Household Air Pollution Exposure and Previous Pulmonary Tuberculosis.
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Autores:
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Emuron, Dennis ;
Siddharthan, Trishul ;
Morgan, Brooks ;
Pollard, Suzanne L. ;
Grigsby, Matthew R. ;
Goodman, Dina ;
Chowdhury, Muhammad ;
Rubinstein, Adolfo ;
Irazola, Vilma ;
Gutierrez, Laura ;
Miranda, J. Jaime ;
Bernabé-Ortiz, Antonio ;
Alam, Dewan ;
Kirenga, Bruce ;
Jones, Rupert ;
van Gemert, Frederik ;
Checkley, William
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Tipo de documento:
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texto impreso
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Editorial:
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Springer Verlag, 2019-12-06T21:04:44Z
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Nota general:
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info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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CONTEXT: Observational studies investigating household air pollution (HAP) exposure to biomass fuel smoke as a risk factor for pulmonary tuberculosis have reported inconsistent results. OBJECTIVE: To evaluate the association between HAP exposure and the prevalence of self-reported previous pulmonary tuberculosis. DESIGN: We analyzed pooled data including 12,592 individuals from five population-based studies conducted in Latin America, East Africa, and Southeast Asia from 2010 to 2015. We used multivariable logistic regression to model the association between HAP exposure and self-reported previous pulmonary tuberculosis adjusted for age, sex, tobacco smoking, body mass index, secondary education, site and country of residence. RESULTS: Mean age was 54.6 years (range of mean age across settings 43.8-59.6 years) and 48.6% were women (range of % women 38.3-54.5%). The proportion of participants reporting HAP exposure was 38.8% (range in % HAP exposure 0.48-99.4%). Prevalence of previous pulmonary tuberculosis was 2.7% (range of prevalence 0.6-6.9%). While participants with previous pulmonary tuberculosis had a lower pre-bronchodilator FEV1 (mean - 0.7 SDs, 95% CI - 0.92 to - 0.57), FVC (- 0.52 SDs, 95% CI - 0.69 to - 0.33) and FEV1/FVC (- 0.59 SDs, 95% CI - 0.76 to - 0.43) as compared to those who did not, we did not find an association between HAP exposure and previous pulmonary tuberculosis (adjusted odds ratio = 0.86; 95% CI 0.56-1.32). CONCLUSIONS: There was no association between HAP exposure and self-reported previous pulmonary tuberculosis in five population-based studies conducted worldwide.
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En línea:
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http://repositorio.upch.edu.pe/handle/upch/7591
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