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Título:
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Prevalence of Pragmatically Defined High CV Risk and its Correlates in LMIC: A Report From 10 LMIC Areas in Africa, Asia, and South America
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Autores:
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Carrillo-Larco, Rodrigo-M. ;
Miranda, J. Jaime ;
Li, Xian ;
Cui, Chendi ;
Xu, Xiaolin ;
Ali, Mohammed ;
Alam, Dewan-S. ;
Gaziano, Thomas-A. ;
Gupta, Rajeev ;
Irazola, Vilma ;
Levitt, Naomi-S. ;
Prabhakaran, Dorairaj ;
Rubinstein, Adolfo ;
Steyn, Krisela ;
Tandon, Nikhil ;
Xavier, Denis ;
Wu, Yangfeng ;
Yan, Lijing-L.
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Tipo de documento:
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texto impreso
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Editorial:
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Elsevier, 2019-02-06T14:45:11Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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BACKGROUND: Currently available tools for assessing high cardiovascular risk (HCR) often require measurements not available in resource-limited settings in low- and middle-income countries (LMIC). There is a need to assess HCR using a pragmatic evidence-based approach. OBJECTIVES: This study sought to report the prevalence of HCR in 10 LMIC areas in Africa, Asia, and South America and to investigate the profiles and correlates of HCR. METHODS: Cross-sectional analysis using data from the National Heart, Lung, and Blood Institute-UnitedHealth Group Centers of Excellence. HCR was defined as history of heart disease/heart attack, history of stroke, older age (>/=50 years for men and >/=60 for women) with history of diabetes, or older age with systolic blood pressure >/=160 mm Hg. Prevalence estimates were standardized to the World Health Organization's World Standard Population. RESULTS: A total of 37,067 subjects ages >/=35 years were included; 53.7% were women and mean age was 53.5 +/- 12.1 years. The overall age-standardized prevalence of HCR was 15.4% (95% confidence interval: 15.0% to 15.7%), ranging from 8.3% (India, Bangalore) to 23.4% (Bangladesh). Among men, the prevalence was 1.7% for the younger age group (35 to 49 years) and 29.1% for the older group (>/=50); among women, 3.8% for the younger group (35 to 59 years) and 40.7% for the older group (>/=60). Among the older group, measured systolic blood pressure >/=160 mm Hg (with or without other conditions) was the most common criterion for having HCR, followed by diabetes. The proportion of having met more than 1 criterion was nearly 20%. Age, education, and body mass index were significantly associated with HCR. Cross-site differences existed and were attenuated after adjusting for age, sex, education, smoking, and body mass index. CONCLUSIONS: The prevalence of HCR in 10 LMIC areas was generally high. This study provides a starting point to define targeted populations that may benefit from interventions combining both primary and secondary prevention strategies.
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En línea:
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http://doi.org/10.1016/j.gheart.2015.12.004
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