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Autor Gonzalez, Armando E. |
Documentos disponibles escritos por este autor (37)
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Arroyo, Gianfranco ; Bustos, Javier A. ; Lescano, Andres G. ; Gonzales, Isidro ; Saavedra, Herbert ; Rodriguez, Silvia ; Pretell, E. Javier ; Bonato, Pierina S. ; Lanchote, Vera L. ; Takayanagui, Osvaldo M. ; Horton, John ; Gonzalez, Armando E. ; Gilman, Robert H. ; Garcia, Hector H. | Oxford University Press | 2019-07-04T16:59:18ZBackground: Albendazole is the drug of choice for the treatment of parenchymal neurocysticercosis, although its efficacy is suboptimal. Plasma levels of albendazole sulfoxide (ASOX), the active metabolite of albendazole, are highly variable amon[...]![]()
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Arroyo, Gianfranco ; Bustos, Javier A. ; Lescano, Andres G. ; Gonzales, Isidro ; Saavedra, Herbert ; Rodriguez, Silvia ; Pretell, E. Javier ; Bonato, Pierina S. ; Lanchote, Vera L. ; Takayanagui, Osvaldo M. ; Horton, John ; Gonzalez, Armando E. ; Gilman, Robert H. ; Garcia, Hector H. | Oxford University Press | 2019-12-06T21:02:55ZBACKGROUND: The efficacy of albendazole therapy in patients with parenchymal neurocysticercosis (NCC) is suboptimal. Plasma levels of albendazole sulfoxide (ASOX), the active metabolite of albendazole, are highly variable among patients. We hypo[...]![]()
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Arroyo, Gianfranco ; Rodriguez, Silvia ; Lescano, Andres G. ; Alroy, Karen A. ; Bustos, Javier A. ; Santivañez, Saul ; Gonzales, Isidro ; Saavedra, Herbert ; Pretell, E. Javier ; Gonzalez, Armando E. ; Gilman, Robert H. ; Tsang, Victor C. W. ; Garcia, Hector H. ; Cysticercosis Working Group in Peru | Oxford University Press | 2018-11-30T02:09:29ZBackground: The enzyme-linked immunoelectrotransfer blot (EITB) assay is the reference serological test for neurocysticercosis (NCC). A positive result on EITB does not always correlate with the presence of active infections in the central nervo[...]![]()
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Garcia, Hector H. ; Gonzalez, Armando E. ; O'Neal, Seth E. ; Gilman, Robert H. | Instituto Nacional de Salud | 2018-11-30T22:50:34ZNeurocysticercosis is the infection of the nervous system by the larvae (cysticerci) of the pork tapeworm Taenia solium. Neurocysticercosis is the major cause of acquired epilepsy worldwide and as such, it represents a global health problem. On [...]![]()
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Mejia Maza, Alan J. ; Carmen-Orozco, Rogger P. ; Carter, Emma ; Dávila, Danitza G. ; Castillo, Gino ; Morales, Jemina D. ; Mamani, Javier ; Gavidia, Cesar ; Alroy, Joseph ; Sterling, Charles R. ; Gonzalez, Armando E. ; Garcia, Hector H. ; Woltjer, Randy L. ; Verastegui, Manuela R. ; Gilman, Robert H. ; Cysticercosis Working Group in Peru | Wiley | 2018-11-30T02:09:30ZNeurocysticercosis is a parasitic brain disease caused by the larval form (Cysticercus cellulosae) of the Taenia solium and is the leading cause of preventable epilepsy world-wide. However, the pathophysiology and relation to the wide range of c[...]![]()
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Beam, Michelle ; Spencer, Angela ; Fernandez, Lauralee ; Atto, Ruth ; Muro, Claudio ; Vilchez, Percy ; Gamboa, Ricardo ; Olaya, Sandra ; Ayvar, Viterbo ; Gonzalez, Armando E. ; Garcia, Hector H. ; O'Neal, Seth E. ; Cysticercosis Working Group in Peru | American Society of Tropical Medicine and Hygiene | 2018-11-30T02:09:30ZInfection of the brain with Taenia solium larvae (neurocysticercosis) is a leading cause of preventable epilepsy worldwide. Effective and sustainable strategies to control parasite transmission in rural endemic communities are needed to prevent [...]![]()
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Alroy, Karen A. ; Arroyo, Gianfranco ; Gilman, Robert H. ; Gonzales-Gustavson, Eloy ; Gallegos, Linda ; Gavidia, Cesar M. ; Verastegui, Manuela ; Rodriguez, Silvia ; López, Teresa ; Gomez-Puerta, Luis A. ; Alroy, Joseph ; Garcia, Hector H. ; Gonzalez, Armando E. ; Cysticercosis Working Group in Peru | American Society of Tropical Medicine and Hygiene | 2018-11-30T02:09:30ZNeurocysticercosis (NCC), the infection of the human central nervous system (CNS) with larval cysts of Taenia solium causes widespread neurological morbidity. Animal models are crucial for studying the pathophysiology and treatment of NCC. Some [...]![]()
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Lescano, Andres G. ; Pray, Ian W. ; Gonzalez, Armando E. ; Gilman, Robert H. ; Tsang, Victor C. W. ; Gamboa, Ricardo ; Guezala, M. Claudia ; Aybar, Viterbo ; Rodriguez, Silvia ; Moulton, Lawrence H. ; Leontsini, Elli ; Gonzalvez, Guillermo ; O'Neal, Seth E. ; Garcia, Hector H. ; Cysticercosis Working Group in Peru | American Society of Tropical Medicine and Hygiene | 2019-07-04T16:59:24ZThe pork tapeworm, Taenia solium, is among the leading causes of preventable epilepsy in the world and is common in rural areas of developing countries where sanitation is limited and pigs have access to human feces. Prior studies in rural vill[...]![]()
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Garcia, Hector H. ; Lescano, Andres G. ; Gonzales, Isidro ; Bustos, Javier A. ; Pretell, E. Javier ; Horton, John ; Saavedra, Herbert ; Gonzalez, Armando E. ; Gilman, Robert H. | Oxford University Press | 2019-02-06T14:45:34ZBACKGROUND: The efficacy of current antiparasitic treatment for cerebral Taenia solium cysticercosis with either albendazole (ABZ) or praziquantel (PZQ) is suboptimal. A recent study demonstrated that combining these 2 antiparasitic drugs improv[...]![]()
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Garcia, Hector H. ; Gonzalez, Armando E. ; Tsang, Victor C. W. ; O'Neal, Seth E. ; Llanos-Zavalaga, Fernando ; Gonzalvez, Guillermo ; Romero, Jaime ; Rodriguez, Silvia ; Moyano, Luz M. ; Ayvar, Viterbo ; Diaz, Andre ; Hightower, Allen ; Craig, Philip S. ; Lightowlers, Marshall W. ; Gauci, Charles G. ; Leontsini, Elli ; Gilman, Robert H. | Massachusetts Medical Society | 2019-02-06T14:45:33ZBACKGROUND: Taeniasis and cysticercosis are major causes of seizures and epilepsy. Infection by the causative parasite Taenia solium requires transmission between humans and pigs. The disease is considered to be eradicable, but data on attempts[...]![]()
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Vargas-Calla, Ana ; Gomez-Puerta, Luis A. ; Calcina, Juan ; Gonzales-Viera, Omar ; Gavidia, Cesar ; Lopez-Urbina, Maria T. ; Garcia, Hector H. ; Gonzalez, Armando E. | Medknow Publications | 2019-02-06T14:52:14ZOBJECTIVE: To assess the efficacy of triclabendazole (TCBZ) in porcine cysticercosis. METHODS: Eighteen naturally infected cysticercosis pigs were divided into 3 groups of 6 individuals each. The first group was treated orally with TCBZ at a sin[...]![]()
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Gomez-Puerta, Lucho ; Vargas-Calla, Ana ; Castillo, Yesenia ; Lopez-Urbina, Maria Teresa ; Dorny, Pierre ; Garcia, Hector H. ; Gonzalez, Armando E. ; O'Neal, Seth E. | BMC | 2019-07-04T16:59:33ZBACKGROUND: Taenia solium is an important zoonotic parasite that infects humans as definitive host (taeniasis) and pigs as intermediate host (cysticercosis). Serological diagnosis of porcine cysticercosis is limited to antigen detection using EL[...]![]()
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Santivanez, Saul J. ; Rodriguez, Mary L. ; Rodriguez, Silvia ; Sako, Yashuito ; Nkouawa, Agathe ; Kobayashi, Yukuharu ; Sotomayor, Alfredo L. ; Peralta, Julio E. ; Valcarcel, Maria ; Gonzalez, Armando E. ; Garcia, Hector H. ; Ito, Akira | American Society for Microbiology | 2019-02-06T14:52:38ZDiagnosis of cystic echinococcosis (CE) is based on the identification of the cyst(s) by imaging, using immunodiagnostic tests mainly as complementary tools in clinical settings. Among the antigens used for immunodiagnosis, previous studies des[...]![]()
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Marzal, Miguel ; Guerra-Giraldez, Cristina ; Paredes, Adriana ; Cangalaya, Carla ; Rivera, Andrea ; Gonzalez, Armando E. ; Mahanty, Siddhartha ; Garcia, Hector H. ; Nash, Theodore E. | Public Library of Science | 2020-06-10T18:12:17ZCysticidal drug treatment of viable Taenia solium brain parenchymal cysts leads to an acute pericystic host inflammatory response and blood brain barrier breakdown (BBB), commonly resulting in seizures. Naturally infected pigs, untreated or trea[...]![]()
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Lee, Chan ; Noh, John ; O'Neal, Seth E. ; Gonzalez, Armando E. ; Garcia, Hector H. ; Handali, Sukwan | Public Library of Science | 2019-12-06T21:02:59ZWe developed a novel and portable fluorescent sensor that integrates a lateral flow assay with a quantum dot (Qdots) label and a mobile phone reader for detection of specific antibodies in human serum. We evaluated the utility of this assay to t[...]![]()
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Bustos, Javier A. ; Arroyo, Gianfranco ; Gilman, Robert H. ; Soto-Becerra, Percy ; Gonzales, Isidro ; Saavedra, Herbert ; Pretell, E. Javier ; Nash, Theodore E. ; O'Neal, Seth E. ; Del Brutto, Oscar H. ; Gonzalez, Armando E. ; Garcia, Hector H. ; Cysticercosis Working Group in Peru | Oxford University Press | 2020-07-14T00:00:59ZBACKGROUND: Neurocysticercosis (NCC) is a major cause of acquired epilepsy in most of the world. Larval cysts in the human brain eventually resolve and either disappear or leave a calcified scar that is associated with seizures. This study asses[...]![]()
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Pajuelo, Monica J. ; Eguiluz, María ; Roncal, Elisa ; Quiñones-García, Stefany ; Clipman, Steven J. ; Calcina, Juan ; Gavidia, Cesar M. ; Sheen, Patricia ; Garcia, Hector H. ; Gilman, Robert H. ; Gonzalez, Armando E. ; Zimic, Mirko ; Cysticercosis Working Group in Peru | Public Library of Science | 2019-01-25T15:18:36ZThe adult Taenia solium, the pork tapeworm, usually lives as a single worm in the small intestine of humans, its only known definitive host. Mechanisms of genetic variation in T. solium are poorly understood. Using three microsatellite markers p[...]![]()
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Moyano, Luz M. ; O'Neal, Seth E. ; Ayvar, Viterbo ; Gonzalvez, Guillermo ; Gamboa, Ricardo ; Vilchez, Percy ; Rodriguez, Silvia ; Reistetter, Joe ; Tsang, Victor C. W. ; Gilman, Robert H. ; Gonzalez, Armando E. ; Garcia, Hector H. | Public Library of Science | 2019-02-06T14:45:56ZBACKGROUND: Neurocysticercosis is a common helminthic infection of the central nervous system and an important cause of adult-onset epilepsy in endemic countries. However, few studies have examined associations between neurologic symptoms, serol[...]![]()
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Cangalaya, Carla ; Zimic, Mirko ; Marzal, Miguel ; Gonzalez, Armando E. ; Guerra-Giraldez, Cristina ; Mahanty, Siddhartha ; Nash, Theodore E. ; Garcia, Hector H. | Public Library of Science | 2019-02-06T14:53:09ZBACKGROUND: Neurocysticercosis (NCC), infection of the central nervous system by Taenia solium cysticerci, is a pleomorphic disease. Inflammation around cysticerci is the major cause of disease but is variably present. One factor modulating the[...]![]()
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Garcia, Hector H. ; Castillo, Yesenia ; Gonzales, Isidro ; Bustos, Javier A. ; Saavedra, Herbert ; Jacob, Louis ; Del Brutto, Oscar H. ; Wilkins, Patricia P. ; Gonzalez, Armando E. ; Gilman, Robert H. ; Cysticercosis Working Group in Peru | Wiley | 2018-11-30T17:17:15ZOBJECTIVE: To evaluate the diagnostic performance of two commercially available ELISA kits, Novalisa® and Ridascreen® , for the detection of antibodies to Taenia solium, compared to serological diagnosis of neurocysticercosis (NCC) by LLGP-EITB [...]![]()
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Vargas-Calla, Ana ; Gomez-Puerta, Luis A. ; Lopez, Maria T. ; Garcia, Hector H. ; Gonzalez, Armando E. ; Cysticercosis Working Group in Peru | Springer Verlag | 2019-07-04T17:00:19ZSeveral studies have been performed to determine specific antigens for the diagnosis of tapeworms. One of these antigens is Tso31, which is used to differentiate Taenia solium and Taenia saginata in human feces. The aim of the present work was t[...]![]()
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Vargas-Calla, Ana ; Gomez-Puerta, Luis A. ; Pajuelo, Monica J. ; Garcia, Hector H. ; Gonzalez, Armando E. ; Cysticercosis Working Group in Peru | American Society of Tropical Medicine and Hygiene | 2018-11-30T17:17:16ZThe aim of this study was to demonstrate the presence of Taenia solium eggs in beetles collected from sources within the natural environment through molecular techniques. Fifty-four pools of beetles were collected in three villages in Piura, Per[...]![]()
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Garvey, Brian T. ; Moyano, Luz M. ; Ayvar, Viterbo ; Rodriguez, Silvia ; Gilman, Robert H. ; Gonzalez, Armando E. ; Garcia, Hector H. ; O'Neal, Seth E. ; Cysticercosis Working Group in Peru | American Society of Tropical Medicine and Hygiene | 2018-11-30T22:50:33ZNeurocysticercosis causes substantial neurologic morbidity in endemic regions around the world. In this cross-sectional study, we describe the frequency of neurocysticercosis among a presumed high-risk group of people in an endemic community in [...]![]()
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Moyano, Luz M. ; Saito, Mayuko ; Montano, Silvia M. ; Gonzalvez, Guillermo ; Olaya, Sandra ; Ayvar, Viterbo ; Gonzalez, Isidro ; Larrauri, Luis ; Tsang, Victor C. W. ; Llanos, Fernando ; Rodriguez, Silvia ; Gonzalez, Armando E. ; Gilman, Robert H. ; Garcia, Hector H. | Public Library of Science | 2020-06-10T18:12:16ZBACKGROUND: The prevalence of epilepsy added to inadequate treatment results in chronic morbidity and considerable mortality in poor populations. Neurocysticercosis (NCC), a helminthic disease of the central nervous system, is a leading cause o[...]![]()
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Arriola, Carmen S. ; Gonzalez, Armando E. ; Gomez-Puerta, Luis A. ; Lopez-Urbina, Maria T. ; Garcia, Hector H. ; Gilman, Robert H. | Public Library of Science | 2020-06-10T18:12:17ZTaenia solium infection causes severe neurological disease in humans. Even though infection and exposure to swine cysticercosis is scattered throughout endemic villages, location of the tapeworm only explains some of the nearby infections and is[...]