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Moreno, Marta ; Tong-Rios, Carlos ; Orjuela-Sanchez, Pamela ; Carrasco-Escobar, Gabriel ; Campo, Brice ; Gamboa, Dionicia ; Winzeler, Elizabeth A. ; Vinetz, Joseph M. | American Chemical Society | 2018-11-30T02:09:31ZIn vitro culture of Plasmodium vivax liver stages underlies key understandings of the fundamental biology of this parasite, particularly the latent, hyponozoite stage, toward drug and vaccine development. Here, we report systematic production of[...]texto impreso
Moreno-Gutierrez, Diamantina ; Llanos-Cuentas, Alejandro ; Luis Barboza, Jose ; Contreras-Mancilla, Juan ; Gamboa, Dionicia ; Rodriguez, Hugo ; Carrasco-Escobar, Gabriel ; Boreux, Raphael ; Hayette, Marie-Pierre ; Beutels, Philippe ; Speybroeck, Niko ; Rosas-Aguirre, Angel | MDPI | 2019-03-05T15:23:27ZBackground: Faced with the resurgence of malaria, malaria surveillance in the Peruvian Amazon incorporated consecutive active case detection (ACD) interventions using light microscopy (LM) as reactive measure in communities with an unusual high [...]texto impreso
Carrasco-Escobar, Gabriel ; Manrique, Edgar ; Ruiz-Cabrejos, Jorge ; Saavedra, Marlon ; Alava, Freddy ; Bickersmith, Sara ; Prussing, Catharine ; Vinetz, Joseph M. ; Conn, Jan E. ; Moreno, Marta ; Gamboa, Dionicia | Public Library of Science | 2019-07-04T17:00:15ZInterest in larval source management (LSM) as an adjunct intervention to control and eliminate malaria transmission has recently increased mainly because long-lasting insecticidal nets (LLINs) and indoor residual spray (IRS) are ineffective aga[...]texto impreso
Carrasco-Escobar, Gabriel ; Miranda-Alban, Julio ; Fernandez-Minope, Carlos ; Brouwer, Kimberly C. ; Torres, Katherine ; Calderón, Maritza ; Gamboa, Dionicia ; Llanos-Cuentas, Alejandro ; Vinetz, Joseph M. | BMC | 2019-01-25T15:18:36ZBACKGROUND: The incidence of malaria due both to Plasmodium falciparum and Plasmodium vivax in the Peruvian Amazon has risen in the past 5 years. This study tested the hypothesis that the maintenance and emergence of malaria in hypoendemic regio[...]texto impreso
Saavedra, Marlon P. ; Conn, Jan E. ; Alava, Freddy ; Carrasco-Escobar, Gabriel ; Prussing, Catharine ; Bickersmith, Sara A. ; Sangama, Jorge L. ; Fernandez-Minope, Carlos ; Guzman, Mitchel ; Tong, Carlos ; Valderrama, Carlos ; Vinetz, Joseph M. ; Gamboa, Dionicia ; Moreno, Marta | BMC | 2019-12-06T20:57:48ZBACKGROUND: Malaria remains an important public health problem in Peru where incidence has been increasing since 2011. Of over 55,000 cases reported in 2017, Plasmodium vivax was the predominant species (76%), with P. falciparum responsible for[...]texto impreso
Saavedra, Marlon P. ; Conn, Jan E. ; Alava, Freddy ; Carrasco-Escobar, Gabriel ; Prussing, Catharine ; Bickersmith, Sara A. ; Sangama, Jorge L. ; Fernandez-Minope, Carlos ; Guzman, Mitchel ; Tong, Carlos ; Valderrama, Carlos ; Vinetz, Joseph M. ; Gamboa, Dionicia ; Moreno, Marta | BMC | 2019-08-08T15:23:47ZBACKGROUND: Malaria remains an important public health problem in Peru where incidence has been increasing since 2011. Of over 55,000 cases reported in 2017, Plasmodium vivax was the predominant species (76%), with P. falciparum responsible for[...]texto impreso
Rosas-Aguirre, Angel ; Speybroeck, Niko ; Llanos-Cuentas, Alejandro ; Rosanas-Urgell, Anna ; Carrasco-Escobar, Gabriel ; Rodriguez, Hugo ; Gamboa, Dionicia ; Contreras-Mancilla, Juan ; Alava, Freddy ; Soares, Irene S. ; Remarque, Edmond ; D Alessandro, Umberto ; Erhart, Annette | Public Library of Science | 2019-02-06T14:53:10ZBACKGROUND: With low and markedly seasonal malaria transmission, increasingly sensitive tools for better stratifying the risk of infection and targeting control interventions are needed. A cross-sectional survey to characterize the current malar[...]texto impreso
Serra-Casas, Elisa ; Manrique, Paulo ; Ding, Xavier C. ; Carrasco-Escobar, Gabriel ; Alava, Freddy ; Gave, Anthony ; Rodriguez, Hugo ; Contreras-Mancilla, Juan ; Rosas-Aguirre, Angel ; Speybroeck, Niko ; Gonzalez, Iveth J. ; Rosanas-Urgell, Anna ; Gamboa, Dionicia | Public Library of Science | 2019-01-25T15:28:05ZBACKGROUND: Loop-mediated isothermal DNA amplification (LAMP) methodology offers an opportunity for point-of-care (POC) molecular detection of asymptomatic malaria infections. However, there is still little evidence on the feasibility of impleme[...]texto impreso
Prussing, Catharine ; Saavedra, Marlon P. ; Bickersmith, Sara A. ; Alava, Freddy ; Guzman, Mitchel ; Manrique, Edgar ; Carrasco-Escobar, Gabriel ; Moreno, Marta ; Gamboa, Dionicia ; Vinetz, Joseph M. ; Conn, Jan E. | Public Library of Science | 2019-07-04T17:00:18ZIn Amazonian Peru, the primary malaria vector, Nyssorhynchus darlingi (formerly Anopheles darlingi), is difficult to target using standard vector control methods because it mainly feeds and rests outdoors. Larval source management could be a use[...]texto impreso
Carrasco-Escobar, Gabriel ; Gamboa, Dionicia ; Castro, Marcia C. ; Bangdiwala, Shrikant I. ; Rodriguez, Hugo ; Contreras-Mancilla, Juan ; Alava, Freddy ; Speybroeck, Niko ; Lescano, Andres G. ; Vinetz, Joseph M. ; Rosas-Aguirre, Angel ; Llanos-Cuentas, Alejandro | Nature Research | 2019-01-25T15:28:05ZMalaria has steadily increased in the Peruvian Amazon over the last five years. This study aimed to determine the parasite prevalence and micro-geographical heterogeneity of Plasmodium vivax parasitaemia in communities of the Peruvian Amazon. Fo[...]texto impreso
Rosas-Aguirre, Angel ; Guzmán-Guzmán, Mitchel ; Gamboa, Dionicia ; Chuquiyauri, Raúl ; Ramirez, Roberson ; Manrique, Paulo ; Carrasco-Escobar, Gabriel ; Puemape, Carmen ; Llanos-Cuentas, Alejandro ; Vinetz, Joseph M. | BMC | 2019-01-25T15:28:05ZBACKGROUND: Understanding the dynamics of malaria transmission in diverse endemic settings is key for designing and implementing locally adapted and sustainable control and elimination strategies. A parasitological and epidemiological survey was[...]texto impreso
Rosas-Aguirre, Angel ; Ponce, Oscar J. ; Carrasco-Escobar, Gabriel ; Speybroeck, Niko ; Contreras-Mancilla, Juan ; Gamboa, Dionicia ; Pozo, Edwar ; Herrera, Socrates ; Llanos-Cuentas, Alejandro | BMC | 2019-02-06T14:53:06ZBACKGROUND: Peru has presented a decreasing malaria trend during the last decade, particularly in areas on northwestern coast; however, a limited number of cases continues to be reported yearly mainly in malaria hotspots. METHODS: A two-phase s[...]texto impreso
Rovira-Vallbona, Eduard ; Contreras-Mancilla, Juan José ; Ramirez, Roberson ; Guzmán-Guzmán, Mitchel ; Carrasco-Escobar, Gabriel ; Llanos-Cuentas, Alejandro ; Vinetz, Joseph M. ; Gamboa, Dionicia ; Rosanas-Urgell, Anna | Public Library of Science | 2019-01-25T15:28:08ZMalaria transmission requires that Anopheles mosquitoes ingest Plasmodium gametocyte stages circulating in the human bloodstream. In the context of malaria elimination, understanding the epidemiology of gametocytes relative to all Plasmodium inf[...]texto impreso
Carrasco-Escobar, Gabriel ; Schwarz, Lara ; Miranda, J. Jaime ; Benmarhnia, Tarik | Nature Research | 2020-07-14T00:01:00ZThis study aims to quantify changes in outdoor (ambient) air pollution exposure from different migration patterns within Peru and quantify its effect on premature mortality. Data on ambient fine particulate matter (PM2.5) was obtained from the N[...]texto impreso
Ruiz-Grosso, Paulo ; Miranda, J. Jaime ; Gilman, Robert H. ; Walker, Blake Byron ; Carrasco-Escobar, Gabriel ; Varela-Gaona, Marco ; Diez-Canseco, Francisco ; Huicho, Luis ; Checkley, William ; Bernabé-Ortiz, Antonio | Elsevier | 2019-02-06T14:52:12ZPURPOSE: To map the geographical distribution and spatial clustering of depressive symptoms cases in an area of Lima, Peru. METHODS: Presence of depressive symptoms suggesting a major depressive episode was assessed using a short version of the [...]
