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White, Sara E. ; Harvey, Steven A. ; Meza, Graciela ; Llanos, Alejandro ; Guzman, Mitchel ; Gamboa, Dionicia ; Vinetz, Joseph M. | BMC | 2018-11-30T02:09:28ZBACKGROUND: A transmission-blocking vaccine (TBV) to prevent malaria-infected humans from infecting mosquitoes has been increasingly considered as a tool for malaria control and elimination. This study tested the hypothesis that a malaria TBV wo[...]texto impreso
Jimenez, Alfons ; Rees-Channer, Roxanne R. ; Perera, Rushini ; Gamboa, Dionicia ; Chiodini, Peter L. ; Gonzalez, Iveth J. ; Mayor, Alfredo ; Ding, Xavier C. | BMC | 2019-01-25T15:02:16ZBACKGROUND: Rapid diagnostic tests (RDTs) are today the most widely used method for malaria diagnosis and are recommended, alongside microscopy, for the confirmation of suspected cases before the administration of anti-malarial treatment. The di[...]texto impreso
Manrique, Paulo ; Hoshi, Mari ; Fasabi, Manuel ; Nolasco, Oscar ; Yori, Pablo ; Calderon, Martiza ; Gilman, Robert H. ; Kosek, Margaret N. ; Vinetz, Joseph M. ; Gamboa, Dionicia | BMC | 2019-02-06T14:53:06ZBACKGROUND: Several platforms have been used to generate the primary data for microsatellite analysis of malaria parasite genotypes. Each has relative advantages but share a limitation of being time- and cost-intensive. A commercially available [...]texto impreso
Alnasser, Yossef ; Ferradas, Cusi ; Clark, Taryn ; Calderón, Maritza ; Gurbillon, Alejandro ; Gamboa, Dionicia ; McKakpo, Uri S. ; Quakyi, Isabella A. ; Bosompem, Kwabena M. ; Sullivan, David J. ; Vinetz, Joseph M. ; Gilman, Robert H. | Public Library of Science | 2019-02-06T14:45:09ZPlasmodium vivax is the most prevalent cause of human malaria in the world and can lead to severe disease with high potential for relapse. Its genetic and geographic diversities make it challenging to control. P. vivax is understudied and to ach[...]texto impreso
Prajapati, Surendra Kumar ; Borlon, Celine ; Rovira-Vallbona, Eduard ; Gruszczyk, Jakub ; Menant, Sebastien ; Tham, Wai-Hong ; Kattenberg, Johanna Helena ; Villasis, Elizabeth ; De Meulenaere, Katlijn ; Gamboa, Dionicia ; Vinetz, Joseph ; Fujita, Ricardo ; Xuan, Xa Nguyen ; Urbano Ferreira, Marcelo ; Nino, Carlos H. ; Patarroyo, Manuel A. ; Spanakos, Gregory ; Kestens, Luc ; Abbeele, Jan Van Den ; Rosanas-Urgell, Anna | Nature Research | 2019-07-04T16:59:26ZPlasmodium vivax parasites preferentially invade reticulocyte cells in a multistep process that is still poorly understood. In this study, we used ex vivo invasion assays and population genetic analyses to investigate the involvement of compleme[...]texto impreso
Moreno, Marta ; Tong-Rios, Carlos ; Orjuela-Sanchez, Pamela ; Carrasco-Escobar, Gabriel ; Campo, Brice ; Gamboa, Dionicia ; Winzeler, Elizabeth A. ; Vinetz, Joseph M. | American Chemical Society | 2018-11-30T02:09:31ZIn vitro culture of Plasmodium vivax liver stages underlies key understandings of the fundamental biology of this parasite, particularly the latent, hyponozoite stage, toward drug and vaccine development. Here, we report systematic production of[...]texto impreso
Ding, Xavier C. ; Ade, Maria Paz ; Baird, J. Kevin ; Cheng, Qin ; Cunningham, Jane ; Dhorda, Mehul ; Drakeley, Chris ; Felger, Ingrid ; Gamboa, Dionicia ; Harbers, Matthias ; Herrera, Socrates ; Lucchi, Naomi ; Mayor, Alfredo ; Mueller, Ivo ; Sattabongkot, Jetsumon ; Ratsimbason, Arsene ; Richards, Jack ; Tanner, Marcel ; Gonzalez, Iveth J. | Public Library of Science | 2019-01-25T15:02:22ZThe global prevalence of malaria has decreased over the past fifteen years, but similar gains have not been realized against Plasmodium vivax because this species is less responsive to conventional malaria control interventions aimed principally[...]texto impreso
Moreno-Gutierrez, Diamantina ; Rosas-Aguirre, Angel ; Llanos-Cuentas, Alejandro ; Bilcke, Joke ; Barboza, José Luis ; Hayette, Marie-Pierre ; Contreras-Mancilla, Juan ; Aguirre, Kristhian ; Gamboa, Dionicia ; Rodriguez, Hugo ; Speybroeck, Niko ; Beutels, Philippe | BMC | 2020-07-14T00:02:35ZBackground: Case management is one of the principal strategies for malaria control. This study aimed to estimate the economic costs of uncomplicated malaria case management and explore the influence of health-seeking behaviours on those costs. M[...]texto impreso
Moreno-Gutierrez, Diamantina ; Llanos-Cuentas, Alejandro ; Luis Barboza, Jose ; Contreras-Mancilla, Juan ; Gamboa, Dionicia ; Rodriguez, Hugo ; Carrasco-Escobar, Gabriel ; Boreux, Raphael ; Hayette, Marie-Pierre ; Beutels, Philippe ; Speybroeck, Niko ; Rosas-Aguirre, Angel | MDPI | 2019-03-05T15:23:27ZBackground: Faced with the resurgence of malaria, malaria surveillance in the Peruvian Amazon incorporated consecutive active case detection (ACD) interventions using light microscopy (LM) as reactive measure in communities with an unusual high [...]texto impreso
Rosas-Aguirre, Angel ; Gamboa, Dionicia ; Manrique, Paulo ; Conn, Jan-E. ; Moreno, Marta ; Lescano, Andres-G. ; Sanchez, Juan-F. ; Rodriguez, Hugo ; Silva, Hermann ; Llanos-Cuentas, Alejandro ; Vinetz, Joseph-M. | American Society of Tropical Medicine and Hygiene | 2019-02-06T14:45:58ZMalaria in Peru, dominated by Plasmodium vivax, remains a public health problem. The 1990s saw newly epidemic malaria emerge, primarily in the Loreto Department in the Amazon region, including areas near to Iquitos, the capital city, but sporad[...]texto impreso
Bendezu, Jorge ; Villasis, Elizabeth ; Morales Ruiz, Sandra ; Garro, Katherine ; Infante, Beronica ; Gutierrez-Loli, Renzo ; Rodriguez, Pamela ; Fernandez-Diaz, Manolo ; Gamboa, Dionicia ; Torres, Katherine | BMC | 2019-12-06T21:02:56ZBACKGROUND: Different antigens are needed to characterize Plasmodium falciparum infection in terms of seroreactivity and targets for invasion inhibition, in order to guide and identify the proper use of such proteins as tools for the development[...]texto impreso
Rougeron, Virginie ; Tiedje, Kathryn E. ; Chen, Donald S. ; Rask, Thomas S. ; Gamboa, Dionicia ; Maestre, Amanda ; Musset, Lise ; Legrand, Eric ; Noya, Oscar ; Yalcindag, Erhan ; Renaud, François ; Prugnolle, Franck ; Day, Karen P. | Wiley Open Access | 2019-01-25T15:18:34ZStrong founder effects resulting from human migration out of Africa have led to geographic variation in single nucleotide polymorphisms (SNPs) and microsatellites (MS) of the malaria parasite, Plasmodium falciparum. This is particularly striking[...]texto impreso
Bordbar, Bita ; Tuikue Ndam, Nicaise ; Renard, Emmanuelle ; Jafari-Guemouri, Sayeh ; Tavul, Livingstone ; Jennison, Charlie ; Gnidehou, Sedami ; Tahar, Rachida ; Gamboa, Dionicia ; Bendezu, Jorge ; Menard, Didier ; Barry, Alyssa E. ; Deloron, Philippe ; Sabbagh, Audrey | Elsevier | 2020-06-10T18:11:30ZIn placental malaria (PM), sequestration of infected erythrocytes in the placenta is mediated by an interaction between VAR2CSA, a Plasmodium falciparum protein expressed on erythrocytes, and chondroitin sulfate A (CSA) on syncytiotrophoblasts. [...]texto impreso
Torres, Katherine J. ; Castrillon, Carlos E. ; Moss, Eli L. ; Saito, Mayuko ; Tenorio, Roy ; Molina, Douglas M. ; Davies, Huw ; Neafsey, Daniel E. ; Felgner, Philip ; Vinetz, Joseph M. ; Gamboa, Dionicia | Oxford University Press | 2019-02-06T14:57:40ZBACKGROUND: Persons with blood-stage Plasmodium falciparum parasitemia in the absence of symptoms are considered to be clinically immune. We hypothesized that asymptomatic subjects with P. falciparum parasitemia would differentially recognize a[...]texto impreso
Carrasco-Escobar, Gabriel ; Manrique, Edgar ; Ruiz-Cabrejos, Jorge ; Saavedra, Marlon ; Alava, Freddy ; Bickersmith, Sara ; Prussing, Catharine ; Vinetz, Joseph M. ; Conn, Jan E. ; Moreno, Marta ; Gamboa, Dionicia | Public Library of Science | 2019-07-04T17:00:15ZInterest in larval source management (LSM) as an adjunct intervention to control and eliminate malaria transmission has recently increased mainly because long-lasting insecticidal nets (LLINs) and indoor residual spray (IRS) are ineffective aga[...]
