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Autor Gotuzzo, E. |
Documentos disponibles escritos por este autor (39)
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Adult T cell lymphocyte leukemia/lymphoma (ATLL) is a subtype of T-cell lymphoma caused by infection of the human T-cell lymphotropic virus type 1 (HTLV-1); which generates a pro-viral integration into the host DNA, resulting in a clonal expansi[...]![]()
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Cannella, A.P. ; Arlehamn, C.S.L. ; Sidney, J. ; Patra, K.P. ; Torres, K. ; Tsolis, R.M. ; Liang, L. ; Felgner, P.L. ; Saito, M. ; Gotuzzo, E. ; Gilman, R.H. ; Sette, A. ; Vinetz, J.M. | American Society for Microbiology | 2020-06-10T18:11:30ZBrucella melitensis, one of the causative agents of human brucellosis, causes acute, chronic, and relapsing infection. While T cell immunity in brucellosis has been extensively studied in mice, no recognized human T cell epitopes that might prov[...]![]()
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Cachay, R. ; Schwalb, A. ; Watanabe, T. ; Guzman, D. ; Jaenisch, T. ; Guillén-Pinto, D. ; Gotuzzo, E. | American Society of Tropical Medicine and Hygiene | 2020-12-14T16:06:11ZWe report the case of an infant born with congenital Zika syndrome (CZS). During the largest Zika virus (ZIKV) outbreak in Peru, the mother presented with fever and rash that were confirmed to be due to ZIKV by real-time PCR. The infant was born[...]![]()
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Menezes, S.M. ; Decanine, D. ; Brassat, D. ; Khouri, R. ; Schnitman, S.V. ; Kruschewsky, R. ; López, G. ; Álvarez, C. ; Talledo, M. ; Gotuzzo, E. ; Vandamme, A.-M. ; Galvão-Castro, B. ; Liblau, R. ; Weyenbergh, J.V. | BMC | 2020-06-10T18:12:16ZBackground: Human T-cell lymphotropic virus (HTLV-1) is the causative agent of the incapacitating, neuroinflammatory disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Currently, there are no disease-modifying therapies[...]![]()
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Shah, L. ; Rojas, M. ; Mori, O. ; Zamudio, C. ; Kaufman, J. S. ; Otero, L. ; Gotuzzo, E. ; Seas, C. ; Brewer, T. F. | Cambridge University Press | 2019-01-25T15:02:22ZWe compared the cost-effectiveness (CE) of an active case-finding (ACF) programme for household contacts of tuberculosis (TB) cases enrolled in first-line treatment to routine passive case-finding (PCF) within an established national TB programm[...]![]()
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Yamakawa, N. ; Yagishita, N. ; Matsuo, T. ; Yamauchi, J. ; Ueno, T. ; Inoue, E. ; Takata, A. ; Nagasaka, M. ; Araya, N. ; Hasegawa, D. ; Coler-Reilly, A. ; Tsutsumi, S. ; Sato, T. ; Araujo, A. ; Casseb, J. ; Gotuzzo, E. ; Jacobson, S. ; Martin, F. ; Puccioni-Sohler, M. ; Taylor, G.P. ; Yamano, Y. | BioMed Central | 2020-12-14T16:11:09ZBackground: Urinary dysfunction is one of the main features of human T-cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). However, a comprehensive assessment of the severity is difficult because a standardiz[...]![]()
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In Peru, it is estimated that about 150 000-400 000 people carry the Human![]()
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In Peru, it is estimated that about 150,000-400,000 people carry the Human T-lymphotropic virus 1 (HTLV-1). Only 10% of HTLV-1 carries develop complications related to HTLV-1. HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) i[...]![]()
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Ballif, M. ; Nhandu, V. ; Wood, R. ; Dusingize, J.C. ; Carter, E.J. ; Cortes, C.P. ; McGowan, C.C. ; Diero, L. ; Graber, C. ; Renner, L. ; Hawerlander, D. ; Kiertiburanakul, S. ; Du, Q.T. ; Sterling, T.R. ; Egger, M. ; Fenner, L. ; Ajayi, S. ; Anastos, K. ; Bashi, J. ; Bishai, W. ; Boulle, A. ; Braitstein, P. ; Carriquiry, G. ; Carter, J.E. ; Cegielski, P. ; Chimbetete, C. ; Conrad, J. ; Davies, M.-A. ; Duda, S. ; Durier, N. ; Eboua, T.F. ; Gasser, A. ; Geng, E. ; Hardwicke, L. ; Hoffmann, C. ; Huebner, R. ; Kancheya, N. ; Kim, P. ; Lameck, D. ; Leroy, V. ; Lewden, C. ; Lindegren, M.L. ; Mandalakas, A. ; Maskew, M. ; McKaig, R. ; Mofenson, L. ; Mpoudi-Etame, M. ; Okwara, B. ; Phiri, S. ; Prasitsuebsai, W. ; Petit, A. ; Prozesky, H. ; Reid, S.E. ; Reubenson, G. ; Sohn, A. ; Vo, Q. ; Walker, D. ; Wehbe, F. ; Wejse, C. ; Wester, W. ; Williams, C. ; Wools-Kaloustian, K. ; Yao, Z. ; Yunihastuti, E. ; Zhang, F.J. ; Zhao, H.X. ; Han, N. ; Merati, T.P. ; Wirawan, D.N. ; Yuliana, F. ; Ditangco, R. ; Uy, E. ; Bantique, R. ; Phanuphak, P. ; Ruxrungtham, K. ; Avihingsanon, A. ; Mengthaisong, T. ; Sungkanuparph, S. ; Sanmeema, N. ; Chaiwarith, R. ; Sirisanthana, T. ; Kotarathititum, W. ; Pham, T.T. ; Cuong, D.D. ; Ha, H.L. ; Nguyen, V.K. ; Bui, V.H. ; Cao, T.T. ; Sohn, A.H. ; Petersen, B. ; Cooper, D.A. ; Law, M.G. ; Jiamsakul, A. ; Boettiger, D.C. ; Wati, D.K. ; Atmikasari, L.P.P. ; Malino, I.Y. ; Nallusamy, R. ; Chan, K.C. ; Lumbiganon, P. ; Kosalaraksa, P. ; Tharnprisan, P. ; Udomphanit, T. ; Chokephaibulkit, K. ; Lapphra, K. ; Phongsamart, W. ; Wittawatmongkol, O. ; Dung, K.T.K. ; Lam, N.V. ; An, P.N. ; Loan, N.T. ; Truong, H.K. ; Du, T.Q. ; Chau, N.H. ; Do, C.V. ; Ha, M.T. ; Nipathakosol, P. ; Kariminia, A. ; Mutimura, E. ; Gitembagara, A. ; Tatwangire, J. ; Izabelle, I. ; Niyongabo, T. ; Twizere, C. ; Baramperanye, E. ; Edmonds, A. ; Yotebieng, M. ; Azinyue, I. ; Ayangma, L. ; Yiannoutsos, C. ; Ayaya, S. ; Bukusi, E.A. ; Lewis-Kulzer, J. ; Somi, G. ; Lyamuya, R. ; Ngonyani, K. ; Ssali, J. ; Ssemuwemba, H. ; Mwebesa, B.B. ; Kambugu, A. ; Hermans, S. ; Nalugoda, F. ; Jjingo, K. ; Dickinsonn, D. ; Eley, B. ; Fritz, C. ; Garone, D. ; Giddy, J. ; MacPhail, P. ; Moultrie, H. ; Ndirangu, J. ; Pestilli, S. ; Rabie, H. ; Stringer, J. ; Technau, K. ; Kaeser, F. ; Keiser, O. ; Cornell, M. ; Maxwell, N. ; Zannou, D.M. ; Ahouada, C. ; Akakpo, J. ; Ahomadegbé, C. ; Gougounon-Houéto, A. ; Azon-Kouanou, A. ; Houngbé, F. ; Sehonou, J. ; Koumakpaï, S. ; Alihonou, F. ; D'Almeida, M. ; Hodonou, I. ; Hounhoui, G. ; Sagbo, G. ; Tossa-Bagnan, L. ; Adjide, H. ; Drabo, J. ; Bognounou, R. ; Dienderé, A. ; Traore, E. ; Zoungrana, L. ; Zerbo, B. ; Sawadogo, A.B. ; Zoungrana, J. ; Héma, A. ; Soré, I. ; Bado, G. ; Tapsoba, A. ; Yé, D. ; Kouéta, F. ; Ouedraogo, S. ; Ouédraogo, R. ; Hiembo, W. ; Gansonré, M. ; Messou, E. ; Gnokoro, J.C. ; Koné, M. ; Kouakou, G.M. ; Bosse, C.A. ; Brou, K. ; Assi, A.I. ; Chenal, H. ; Soppi, F. ; Minga, A. ; Abo, Y. ; Eholié, S.P. ; Amego, M.D.N. ; Andavi, V. ; Diallo, Z. ; Ello, F. ; Tanon, A.K. ; Koule, S.O. ; Anzan, K.C. ; Guehi, C. ; Aka, E.A. ; Issouf, K.L. ; Kouakou, J.-C. ; N'Gbeche, M.-S. ; Pety, T. ; Avit-Edi, D. ; Kouakou, K. ; Moh, M. ; Yao, V.A. ; Folquet, M.A. ; Dainguy, M.-E. ; Kouakou, C. ; Méa-Assande, V.T. ; Oka-Berete, G. ; Zobo, N. ; Acquah, P. ; Kokora, M.-B. ; Eboua, T.F. ; Timité-Konan, M. ; Diecket Ahoussou, L. ; Assouan, J.K. ; Sami, M.F. ; Kouadio, S. ; Goka, B. ; Welbeck, J. ; Sackey, A. ; Owiafe, S.N. ; Da Silva, Z.J. ; Paulo, J. ; Rodrigues, A. ; Da Silva, D. ; Medina, C. ; Oliviera-Souto, I. ; Østergaard, L. ; Laursen, A. ; Sodemann, M. ; Aaby, P. ; Fomsgaard, A. ; Erikstrup, C. ; Eugen-Olsen, J. ; Maïga, M.Y. ; Diakité, F.F. ; Kalle, A. ; Katile, D. ; Traore, H.A. ; Minta, D. ; Cissé, T. ; Dembelé, M. ; Doumbia, M. ; Fomba, M. ; Kaya, A.S. ; Traoré, A.M. ; Traoré, H. ; Toure, A.A. ; Dicko, F. ; Sylla, M. ; Berthé, A. ; Traoré, H.C. ; Koïta, A. ; Koné, N. ; N'Diaye, C. ; Coulibaly, S.T. ; Traoré, M. ; Traoré, N. ; Charurat, M. ; Alim, G. ; Dapiap, S. ; Igbinoba, F. ; Benson, O. ; Adebamowo, C. ; James, J. ; Obaseki ; Osakede, P. ; Olasode, J. ; Seydi, M. ; Sow, P.S. ; Diop, B. ; Manga, N.M. ; Tine, J.M. ; Bassabi, C.C. ; Sy, H.S. ; Ba, A. ; Diagne, A. ; Dior, H. ; Faye, M. ; Gueye, R.D. ; Mbaye, A.D. ; Patassi, A. ; Kotosso, A. ; Kariyare, B.G. ; Gbadamassi, G. ; Komi, A. ; Mensah-Zukong, K.E. ; Pakpame, P. ; Koko Lawson-Evi, A. ; Atakouma, Y. ; Takassi, E. ; Djeha, A. ; Ephoévi-gah, A. ; El-Hadj Djibril, S. ; Dabis, F. ; Bissagnene, E. ; Arrivé, E. ; Coffie, P. ; Ekouevi, D. ; Jaquet, A. ; Sasco, A.J. ; Amani, D. ; Azani, J.-C. ; Balestre, E. ; Bessekon, S. ; Bohossou, F. ; Gilbert, C. ; Karcher, S. ; Gonsan, J.M. ; Le Carrou, J. ; Lenaud, S. ; Nchot, C. ; Malateste, K. ; Yao, A.R. ; Siloué, B. ; Clouet, G. ; Dosso, M. ; Doring, A. ; Kouakou, A. ; Rabourdin, E. ; Rivenc, J. ; Anglaret, X. ; Ba, B. ; Essanin, J.B. ; Ciaranello, A. ; Datté, S. ; Desmonde, S. ; Elvis Diby, J.-S. ; Gottlieb, G.S. ; Horo, A.G. ; Kangah, S.N. ; Malvy, D. ; Meless, D. ; Mounkaila-Harouna, A. ; Ndondoki, C. ; Shiboski, C. ; Tchounga, B. ; Thiébaut, R. ; Wandeler, G. ; McGowan, C. ; Cahn, P. ; Gotuzzo, E. ; Wolff, M. ; Grinsztejn, B. ; Pape, J. ; Padgett, D. ; Madero, J.S. | International Union Against Tuberculosis and Lung Disease | 2020-06-10T18:11:32ZSETTING: Drug resistance threatens tuberculosis (TB) control, particularly among human immunodeficiency virus (HIV) infected persons. OBJECTIVE: To describe practices in the prevention and management of drug-resistant TB under antiretroviral the[...]![]()
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Broger, T. ; Nicol, M.P. ; Sigal, G.B. ; Gotuzzo, E. ; Zimmer, A.J. ; Surtie, S. ; Caceres-Nakiche, T. ; Mantsoki, A. ; Reipold, E.I. ; Székely, R. ; Tsionsky, M. ; van Heerden, J. ; Plisova, T. ; Chikamatsu, K. ; Lowary, T.L. ; Pinter, A. ; Mitarai, S. ; Moreau, E. ; Schumacher, S.G. ; Denkinger, C.M. | American Society for Clinical Investigation | 2020-12-14T16:06:09ZBACKGROUND. Inadequate tuberculosis (TB) diagnostics are a major hurdle in the reduction of disease burden, and accurate point-of-care tests (POCTs) are urgently needed. We assessed the diagnostic accuracy of Fujifilm SILVAMP TB lipoarabinomanna[...]![]()
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Schwalb, A. ; Pérez-Muto, V. ; Cachay, R. ; Tipismana, M. ; Álvarez, C. ; Mejia, F. ; González-Lagos, E. ; Gotuzzo, E. | MDPI AG | 2020-12-14T16:10:12ZBackground: Vertical transmission of HTLV-1 could lead to the early development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). This significantly affects quality of life and increases morbimortality. Objective: To descri[...]![]()
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Maco, V. ; Marcos, L. ; Delgado, J. ; Herrera, J. ; Nestares, J. ; Terashima, A. ; Samalvides, F. ; Gotuzzo, E. | Sociedade Brasileira de Medicina Tropical | 2019-04-24T18:23:57ZIntroduction: The therapeutic scheme of triclabendazole (TCBZ), the recommended anthelmintic against Fasciola hepatica, involves 10mg/kg of body weight administered in a single dose; however, clinical trials in children are scarce. We evaluated [...]![]()
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Acosta, F. ; Agapito, J. ; Cabibbe, A.M. ; Cáceres, T. ; Sola, C. ; Pérez-Lago, L. ; Abascal, E. ; Herranz, M. ; Meza, E. ; Klotoe, B. ; Muñoz, P. ; Rossolini, G.M. ; Bartoloni, A. ; Tortoli, E. ; Cirillo, D.M. ; Gotuzzo, E. ; García De Viedma, D. | Centers for Disease Control and Prevention | 2019-07-04T16:59:34ZWe performed a cross-border molecular epidemiology analysis of multidrug-resistant tuberculosis in Peru, Spain, and Italy. This analysis revealed frequent transmission in Peru and exportation of a strain that recreated similar levels of transmis[...]![]()
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Shah, L. ; Choi, H. W. ; Berrang-Ford, L. ; Henostroza, G. ; Krapp, F. ; Zamudio, C. ; Heymann, S. J. ; Kaufman, J. S. ; Ciampi, A. ; Seas, C. ; Gotuzzo, E. ; Brewer, T. F. | International Union Against Tuberculosis and Lung Disease | 2020-06-10T18:11:30ZSETTING: Peru reports among the highest multidrug-resistant tuberculosis (MDR-TB) rates in the Americas, with a growing proportion in previously untreated tuberculosis (TB) cases. The identification of clusters of primary MDR-TB compared with dr[...]![]()
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Cesar, C. ; Koethe, J.R. ; Giganti, M.J. ; Rebeiro, P. ; Althoff, K.N. ; Napravnik, S. ; Mayor, A. ; Grinsztejn, B. ; Wolff, M. ; Padgett, D. ; Sierra Madero, J. ; Gotuzzo, E. ; Sterling, T.R. ; Willig, J. ; Levison, J. ; Kitahata, M. ; Rodriguez-Barradas, M.C. ; Moore, R.D. ; McGowan, C. ; Shepherd, B.E. ; Cahn, P. | Wiley Open Access | 2019-04-24T18:23:55ZIntroduction: Latinos living with HIV in the Americas share a common ethnic and cultural heritage. In North America, Latinos have a relatively high rate of new HIV infections but lower rates of engagement at all stages of the care continuum, whe[...]![]()
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Loiseau, C. ; Brites, D. ; Reinhard, M. ; Zürcher, K. ; Borrell, S. ; Ballif, M. ; Fenner, L. ; Cox, H. ; Rutaihwa, L.K. ; Wilkinson, R.J. ; Yotebieng, M. ; Jane Carter, E. ; Abimiku, A. ; Marcy, O. ; Gotuzzo, E. ; Avihingsanon, A. ; Zetola, N. ; Doulla, B. ; Böttger, E.C. ; Egger, M. ; Gagneux, S. | American Society for Microbiology | 2020-12-14T16:06:29ZWe analyzed 312 drug-resistant genomes of Mycobacterium tuberculosis isolates collected from HIV-coinfected and HIV-negative TB patients from nine countries with a high tuberculosis burden. We found that rifampicin-resistant M. tuberculosis stra[...]![]()
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Crabtree-Ramírez, B. ; Jenkins, C. ; Jayathilake, K. ; Carriquiry, G. ; Veloso, V. ; Padgett, D. ; Gotuzzo, E. ; Cortes, C. ; Mejia, F. ; McGowan, C.C. ; Duda, S. ; Shepherd, B.E. ; Sterling, T.R. | International Union Against Tuberculosis and Lung Disease | 2019-07-04T17:00:15ZBACKGROUND: Tuberculosis (TB) diagnosis in human immunodeficiency virus (HIV) positive persons is difficult, particularly in resource-limited settings. The relationship between TB culture status and mortality in HIV-positive persons treated for [...]![]()
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Crabtree-Ramírez, B. ; Jenkins, C. ; Jayathilake, K. ; Carriquiry, G. ; Veloso, V. ; Padgett, D. ; Gotuzzo, E. ; Cortes, C. ; Mejia, F. ; McGowan, C.C. ; Duda, S. ; Shepherd, B.E. ; Sterling, T.R. | International Union Against Tuberculosis and Lung Disease | 2019-12-06T20:57:49ZBACKGROUND: Tuberculosis (TB) diagnosis in human immunodeficiency virus (HIV) positive persons is difficult, particularly in resource-limited settings. The relationship between TB culture status and mortality in HIV-positive persons treated for [...]![]()
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Valenzuela, C. ; Ugarte-Gil, C. ; Paz, J. ; Echevarria, J. ; Gotuzzo, E. ; Vermund, S.H. ; Kipp, A.M. | Springer | 2019-02-22T14:55:29ZHIV stigma as a barrier to retention in HIV care has not been well-studied outside the United States. We conducted a case–control study in Lima, Peru to examine this issue. Cases were out-of-care for ?12 months (n = 66) and controls were recruit[...]![]()
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Julca-Copello, P. ; Schwalb, A. ; Cachay, R. ; Tipismana, M. ; Álvarez, C. ; Mejia, F. ; González-Lagos, E. ; Gotuzzo, E. | Sociedade Brasileira de Medicina Tropical | 2020-12-14T16:06:26ZIntroduction: In patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) gait disturbance is a predominant feature that leads to falls and fractures, which can further aggravate disability. We sought to evaluate the imp[...]![]()
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Cesar, C. ; Jenkins, C.A. ; Shepherd, B.E. ; Padgett, D. ; Mejia, F. ; Ribeiro, S.R. ; Cortes, C.P. ; Pape, J.W. ; Sierra Madero, J. ; Fink, V. ; Sued, O. ; McGowan, C. ; Cahn, P. ; Grinsztejn, B. ; Reyes, M.W. ; Gotuzzo, E. ; CCASAnet | Elsevier | 2019-04-24T18:23:55ZBackground: Access to combination antiretroviral therapy (ART) is expanding in Latin America (Mexico, Central America, and South America) and the Caribbean. We assessed the incidence of and factors associated with regimen failure and regimen cha[...]![]()
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Cachay, R. ; Schwalb, A. ; Mora, R. ; Cáceres, T. ; Gotuzzo, E. | Instituto Nacional de Salud | 2019-12-06T21:04:51Z![]()
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La leucemia/linfoma T del adulto (LLTA) de tipo linfomatoso es un subtipo del linfoma de las células T, causado por la infección del virus linfotrópico de células T humanas tipo 1 (HTLV-1); el cual genera una integración proviral en el ADN del h[...]![]()
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Clouse, K. ; Blevins, M. ; Lindegren, M.L. ; Yotebieng, M. ; Nguyen, D.T. ; Omondi, A. ; Michael, D. ; Zannou, D.M. ; Carriquiry, G. ; Pettit, A. ; IeDEA ; Gotuzzo, E. ; Mejia, F. ; Carriquiry, G. | Public Library of Science | 2019-04-24T18:23:56ZObjective: Xpert MTB/RIF is recommended by the World Health Organization (WHO) as the initial tuberculosis (TB) diagnostic test in individuals suspected of HIV-associated TB. We sought to evaluate field implementation of Xpert among a cohort of [...]![]()
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Quispe, R. ; Valle, G. A. ; Huapaya, J. A. ; Novoa, I. ; Giraldo, J. ; Cáceres, T. ; Gotuzzo, E. ; Zamudio, C. ; Seas, C. | International Union Against Tuberculosis and Lung Disease | 2019-02-06T14:45:58ZOBJECTIVE: To evaluate the diagnostic performance of manual MGIT (MMGIT) compared to the gold standard, Lowenstein-Jensen (LJ), in the diagnosis of pulmonary tuberculosis (TB) in a high-burden setting. METHODS: Individuals with suspected TB enro[...]![]()
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Belaunzarán-Zamudio, P.F. ; Caro-Vega, Y.N. ; Shepherd, B.E. ; Crabtree-Ramírez, B.E. ; Luz, P.M. ; Grinsztejn, B. ; Cesar, C. ; Cahn, P. ; Cortes, C. ; Wolff, M. ; Pape, J.W. ; Padgett, D. ; Gotuzzo, E. ; McGowan, C. ; Sierra-Madero, J.G. ; CCASAnet | World Health Organization | 2019-04-24T18:23:51ZObjective To determine the prevalence of adequate monitoring and the costs of measuring CD4+ T-lymphocytes (CD4+ cell) and human immunodeficiency virus (HIV) viral load in people receiving antiretroviral therapy (ART) in seven countries in the W[...]![]()
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Carriquiry, G. ; Fink, V. ; Koethe, J.R. ; Giganti, M.J. ; Jayathilake, K. ; Blevins, M. ; Cahn, P. ; Grinsztejn, B. ; Wolff, M. ; Pape, J.W. ; Padgett, D. ; Sierra Madero, J. ; Gotuzzo, E. ; McGowan, C.C. ; Shepherd, B.E. | Wiley Open Access | 2019-04-24T18:23:55ZIntroduction: Long-term survival of HIV patients after initiating highly active antiretroviral therapy (ART) has not been sufficiently described in Latin America and the Caribbean, as compared to other regions. The aim of this study was to descr[...]![]()
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Diacon, A.H. ; Pym, A. ; Grobusch, M.P. ; De Los Rios, J.M. ; Gotuzzo, E. ; Vasilyeva, I. ; Leimane, V. ; Andries, K. ; Bakare, N. ; De Marez, T. ; Haxaire-Theeuwes, M. ; Lounis, N. ; Meyvisch, P. ; De Paepe, E. ; Van Heeswijk, R.P.G. ; Dannemann, B. | Massachusetts Medical Society | 2020-06-10T18:12:14ZBACKGROUND: Bedaquiline (Sirturo, TMC207), a diarylquinoline that inhibits mycobacterial ATP synthase, has been associated with accelerated sputum-culture conversion in patients with multidrug-resistant tuberculosis, when added to a preferred ba[...]![]()
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Sudbury, E.L. ; Otero, L. ; Tebruegge, M. ; Messina, N.L. ; Seas, C. ; Montes, M. ; Rìos, J. ; Germano, S. ; Gardiner, K. ; Clifford, V. ; Gotuzzo, E. ; Curtis, N. | Elsevier | 2019-07-04T17:00:19ZThe tuberculin skin test and interferon-gamma release assays have limitations in diagnosing tuberculosis (TB), particularly in children. This study investigated the performance of candidate M. tuberculosis-specific cytokine biomarkers for TB in [...]![]()
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Henriquez-Camacho, C. ; Villafuerte-Gutierrez, P. ; Pérez-Molina, J.A. ; Losa, J. ; Gotuzzo, E. ; Cheyne, N. | Wiley | 2019-04-24T18:23:52ZObjectives: International health agencies have promoted nontargeted universal (opt-out) HIV screening tests in different settings, including emergency departments (EDs). We performed a systematic review and meta-analysis to assess the testing up[...]![]()
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Shah, L. ; Rojas Peña, M. ; Mori, O. ; Zamudio, C. ; Kaufman, J.S. ; Otero, L. ; Gotuzzo, E. ; Seas, C. ; Brewer, T.F. | Elsevier B.V. | 2020-12-14T16:10:13ZBackground: Active case finding (ACF) in household contacts of tuberculosis (TB) patients is now recommended for National TB Programs (NTP) in low- and middle-income countries. However, evidence supporting these recommendations remains limited. [...]![]()
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Buonfrate, D. ; Mena, M. A. ; Angheben, A. ; Requena-Méndez, A. ; Munoz, J. ; Gobbi, F. ; Albonico, M. ; Gotuzzo, E. ; Bisoffi, Z. | Cambridge University Press | 2019-02-06T14:52:19ZStrongyloides stercoralis is rarely recognized as a major public health issue, probably because its burden is largely underestimated. We reviewed the literature (both PubMed and 'grey' literature) about the prevalence of strongyloidiasis in Lati[...]![]()
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Soto, A. ; Quiñones-Laveriano, D.M. ; Garcia, P.J. ; Gotuzzo, E. ; Henao-Restrepo, A.M. | Instituto Nacional de Salud | 2020-12-14T16:11:19ZCOVID-19 represents a global crisis. Rapidly conducting a clinical trial with the rigor necessary to obtain reliable results requires the collaboration of various participants involved in the development, evaluation and authorization of clinical[...]![]()
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Ramírez, J.D. ; Sordillo, E.M. ; Gotuzzo, E. ; Zavaleta, C. ; Caplivski, D. ; Navarro, J.C. ; Crainey, J.L. ; Luz, S.L.B. ; Delgado Noguera, L.A. ; Schaub, R. ; Rousseau, C. ; Herrera, G. ; Oliveira-Miranda, M.A. ; Quispe-Vargas, M.T. ; Hotez, P.J. ; Mondolfi, A.P. | Public Library of Science | 2020-12-14T16:10:06ZAs the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic contin-ues to expand, healthcare resources globally have been spread thin. Now, the disease is rapidly spreading across South America, with deadly consequences in areas[...]![]()
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Gallo, R.C. ; Willems, L. ; Hasegawa, H. ; Accolla, R. ; Bangham, C. ; Bazarbachi, A. ; Bertazzoni, U. ; De Freitas Carneiro-Proietti, A.B. ; Cheng, H. ; Chieco-Bianchi, L. ; Ciminale, V. ; Gessain, A. ; Gotuzzo, E. ; Hall, W. ; Harford, J. ; Hermine, O. ; Jacobson, S. ; Macchi, B. ; Macpherson, C. ; Mahieux, R. ; Matsuoka, M. ; McSweegan, E. ; Murphy, E.L. ; Péloponèse, J.-M. ; Reis, J. ; Simon, V. ; Tagaya, Y. ; Taylor, G.P. ; Watanabe, T. ; Yamano, Y. | American Society of Hematology | 2019-04-25T15:46:36Z[Resumen no disponible]![]()
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Seas, C. ; García, Coralith ; Salles, M. J. ; Labarca, J. ; Luna, C. ; Alvarez-Moreno, C. ; Mejía-Villatoro, C. ; Zurita, J. ; Guzmán-Blanco, M. ; Rodríguez-Noriega, E. ; Reyes, J. ; Arias, C. A. ; Carcamo, C. ; Gotuzzo, E. | Oxford University Press | 2018-03-22T23:38:48Z"Substantial heterogeneity in the epidemiology and management of Staphylococcus aureus bacteraemia (SAB) occurs in Latin America. We conducted a prospective cohort study in 24 hospitals from nine Latin American countries. To assess the clinical [...]![]()
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Cabello-Vílchez, A.M. ; Reyes-Batlle, M. ; Montalbán-Sandoval, E. ; Martín-Navarro, C.Ma. ; López-Arencibia, A. ; Elias-Letts, R. ; Guerra, H. ; Gotuzzo, E. ; Martínez-Carretero, E. ; Piñero, J.E. ; Maciver, S.K. ; Valladares, B. ; Lorenzo-Morales, J. | Springer Verlag | 2020-06-10T18:12:13ZBalamuthia mandrillaris is an opportunistic free-living amoeba that has been reported to cause skin lesions and the fatal Balamuthia amoebic encephalitis (BAE) in humans and other animals. Currently, around 200 human BAE cases have been reported[...]![]()
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Belaunzarán-Zamudio, P.F. ; Caro-Vega, Y.N. ; Shepherd, B.E. ; Rebeiro, P.F. ; Crabtree-Ramírez, B.E. ; Cortes, C.P. ; Grinsztejn, B. ; Gotuzzo, E. ; Mejia, F. ; Padgett, D. ; Pape, J.W. ; Rouzier, V. ; Veloso, V. ; Cardoso, S.W. ; McGowan, C.C. ; Sierra-Madero, J.G. ; Caribbean, Central and South America network for HIV epidemiology (CCASAnet) | Oxford University Press | 2020-12-14T16:06:06ZLate presentation to care and antiretroviral therapy (ART) initiation with advanced human immunodeficiency virus (HIV) disease are common in Latin America. We estimated the impact of these conditions on mortality in the region. We included adult[...]![]()
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Otero, L. ; De Orbegoso, A. ; Navarro, A. F. ; Rìos, J. ; Parraga, T. ; Gotuzzo, E. ; Seas, C. ; Van der Stuyft, P. | Wiley | 2019-02-06T14:57:42ZOBJECTIVE: To determine the time from diagnosis to start of multidrug resistant tuberculosis (MDR TB) treatment in Lima, Peru. METHODS: We studied new smear-positive TB adults that were started on MDR TB treatment or that were switched to it bet[...]