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Adult T cell lymphocyte leukemia/lymphoma (ATLL) is a subtype of T-cell lymphoma caused by infection of the human T-cell lymphotropic virus type 1 (HTLV-1); which generates a pro-viral integration into the host DNA, resulting in a clonal expansi[...]texto impreso
Cannella, A.P. ; Arlehamn, C.S.L. ; Sidney, J. ; Patra, K.P. ; Torres, K. ; Tsolis, R.M. ; Liang, L. ; Felgner, P.L. ; Saito, M. ; Gotuzzo, E. ; Gilman, R.H. ; Sette, A. ; Vinetz, J.M. | American Society for Microbiology | 2020-06-10T18:11:30ZBrucella melitensis, one of the causative agents of human brucellosis, causes acute, chronic, and relapsing infection. While T cell immunity in brucellosis has been extensively studied in mice, no recognized human T cell epitopes that might prov[...]texto impreso
Cachay, R. ; Schwalb, A. ; Watanabe, T. ; Guzman, D. ; Jaenisch, T. ; Guillén-Pinto, D. ; Gotuzzo, E. | American Society of Tropical Medicine and Hygiene | 2020-12-14T16:06:11ZWe report the case of an infant born with congenital Zika syndrome (CZS). During the largest Zika virus (ZIKV) outbreak in Peru, the mother presented with fever and rash that were confirmed to be due to ZIKV by real-time PCR. The infant was born[...]texto impreso
Menezes, S.M. ; Decanine, D. ; Brassat, D. ; Khouri, R. ; Schnitman, S.V. ; Kruschewsky, R. ; López, G. ; Álvarez, C. ; Talledo, M. ; Gotuzzo, E. ; Vandamme, A.-M. ; Galvão-Castro, B. ; Liblau, R. ; Weyenbergh, J.V. | BMC | 2020-06-10T18:12:16ZBackground: Human T-cell lymphotropic virus (HTLV-1) is the causative agent of the incapacitating, neuroinflammatory disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Currently, there are no disease-modifying therapies[...]texto impreso
Shah, L. ; Rojas, M. ; Mori, O. ; Zamudio, C. ; Kaufman, J. S. ; Otero, L. ; Gotuzzo, E. ; Seas, C. ; Brewer, T. F. | Cambridge University Press | 2019-01-25T15:02:22ZWe compared the cost-effectiveness (CE) of an active case-finding (ACF) programme for household contacts of tuberculosis (TB) cases enrolled in first-line treatment to routine passive case-finding (PCF) within an established national TB programm[...]texto impreso
Yamakawa, N. ; Yagishita, N. ; Matsuo, T. ; Yamauchi, J. ; Ueno, T. ; Inoue, E. ; Takata, A. ; Nagasaka, M. ; Araya, N. ; Hasegawa, D. ; Coler-Reilly, A. ; Tsutsumi, S. ; Sato, T. ; Araujo, A. ; Casseb, J. ; Gotuzzo, E. ; Jacobson, S. ; Martin, F. ; Puccioni-Sohler, M. ; Taylor, G.P. ; Yamano, Y. | BioMed Central | 2020-12-14T16:11:09ZBackground: Urinary dysfunction is one of the main features of human T-cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). However, a comprehensive assessment of the severity is difficult because a standardiz[...]texto impreso
In Peru, it is estimated that about 150 000-400 000 people carry the Humantexto impreso
In Peru, it is estimated that about 150,000-400,000 people carry the Human T-lymphotropic virus 1 (HTLV-1). Only 10% of HTLV-1 carries develop complications related to HTLV-1. HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) i[...]texto impreso
Ballif, M. ; Nhandu, V. ; Wood, R. ; Dusingize, J.C. ; Carter, E.J. ; Cortes, C.P. ; McGowan, C.C. ; Diero, L. ; Graber, C. ; Renner, L. ; Hawerlander, D. ; Kiertiburanakul, S. ; Du, Q.T. ; Sterling, T.R. ; Egger, M. ; Fenner, L. ; Ajayi, S. ; Anastos, K. ; Bashi, J. ; Bishai, W. ; Boulle, A. ; Braitstein, P. ; Carriquiry, G. ; Carter, J.E. ; Cegielski, P. ; Chimbetete, C. ; Conrad, J. ; Davies, M.-A. ; Duda, S. ; Durier, N. ; Eboua, T.F. ; Gasser, A. ; Geng, E. ; Hardwicke, L. ; Hoffmann, C. ; Huebner, R. ; Kancheya, N. ; Kim, P. ; Lameck, D. ; Leroy, V. ; Lewden, C. ; Lindegren, M.L. ; Mandalakas, A. ; Maskew, M. ; McKaig, R. ; Mofenson, L. ; Mpoudi-Etame, M. ; Okwara, B. ; Phiri, S. ; Prasitsuebsai, W. ; Petit, A. ; Prozesky, H. ; Reid, S.E. ; Reubenson, G. ; Sohn, A. ; Vo, Q. ; Walker, D. ; Wehbe, F. ; Wejse, C. ; Wester, W. ; Williams, C. ; Wools-Kaloustian, K. ; Yao, Z. ; Yunihastuti, E. ; Zhang, F.J. ; Zhao, H.X. ; Han, N. ; Merati, T.P. ; Wirawan, D.N. ; Yuliana, F. ; Ditangco, R. ; Uy, E. ; Bantique, R. ; Phanuphak, P. ; Ruxrungtham, K. ; Avihingsanon, A. ; Mengthaisong, T. ; Sungkanuparph, S. ; Sanmeema, N. ; Chaiwarith, R. ; Sirisanthana, T. ; Kotarathititum, W. ; Pham, T.T. ; Cuong, D.D. ; Ha, H.L. ; Nguyen, V.K. ; Bui, V.H. ; Cao, T.T. ; Sohn, A.H. ; Petersen, B. ; Cooper, D.A. ; Law, M.G. ; Jiamsakul, A. ; Boettiger, D.C. ; Wati, D.K. ; Atmikasari, L.P.P. ; Malino, I.Y. ; Nallusamy, R. ; Chan, K.C. ; Lumbiganon, P. ; Kosalaraksa, P. ; Tharnprisan, P. ; Udomphanit, T. ; Chokephaibulkit, K. ; Lapphra, K. ; Phongsamart, W. ; Wittawatmongkol, O. ; Dung, K.T.K. ; Lam, N.V. ; An, P.N. ; Loan, N.T. ; Truong, H.K. ; Du, T.Q. ; Chau, N.H. ; Do, C.V. ; Ha, M.T. ; Nipathakosol, P. ; Kariminia, A. ; Mutimura, E. ; Gitembagara, A. ; Tatwangire, J. ; Izabelle, I. ; Niyongabo, T. ; Twizere, C. ; Baramperanye, E. ; Edmonds, A. ; Yotebieng, M. ; Azinyue, I. ; Ayangma, L. ; Yiannoutsos, C. ; Ayaya, S. ; Bukusi, E.A. ; Lewis-Kulzer, J. ; Somi, G. ; Lyamuya, R. ; Ngonyani, K. ; Ssali, J. ; Ssemuwemba, H. ; Mwebesa, B.B. ; Kambugu, A. ; Hermans, S. ; Nalugoda, F. ; Jjingo, K. ; Dickinsonn, D. ; Eley, B. ; Fritz, C. ; Garone, D. ; Giddy, J. ; MacPhail, P. ; Moultrie, H. ; Ndirangu, J. ; Pestilli, S. ; Rabie, H. ; Stringer, J. ; Technau, K. ; Kaeser, F. ; Keiser, O. ; Cornell, M. ; Maxwell, N. ; Zannou, D.M. ; Ahouada, C. ; Akakpo, J. ; Ahomadegbé, C. ; Gougounon-Houéto, A. ; Azon-Kouanou, A. ; Houngbé, F. ; Sehonou, J. ; Koumakpaï, S. ; Alihonou, F. ; D'Almeida, M. ; Hodonou, I. ; Hounhoui, G. ; Sagbo, G. ; Tossa-Bagnan, L. ; Adjide, H. ; Drabo, J. ; Bognounou, R. ; Dienderé, A. ; Traore, E. ; Zoungrana, L. ; Zerbo, B. ; Sawadogo, A.B. ; Zoungrana, J. ; Héma, A. ; Soré, I. ; Bado, G. ; Tapsoba, A. ; Yé, D. ; Kouéta, F. ; Ouedraogo, S. ; Ouédraogo, R. ; Hiembo, W. ; Gansonré, M. ; Messou, E. ; Gnokoro, J.C. ; Koné, M. ; Kouakou, G.M. ; Bosse, C.A. ; Brou, K. ; Assi, A.I. ; Chenal, H. ; Soppi, F. ; Minga, A. ; Abo, Y. ; Eholié, S.P. ; Amego, M.D.N. ; Andavi, V. ; Diallo, Z. ; Ello, F. ; Tanon, A.K. ; Koule, S.O. ; Anzan, K.C. ; Guehi, C. ; Aka, E.A. ; Issouf, K.L. ; Kouakou, J.-C. ; N'Gbeche, M.-S. ; Pety, T. ; Avit-Edi, D. ; Kouakou, K. ; Moh, M. ; Yao, V.A. ; Folquet, M.A. ; Dainguy, M.-E. ; Kouakou, C. ; Méa-Assande, V.T. ; Oka-Berete, G. ; Zobo, N. ; Acquah, P. ; Kokora, M.-B. ; Eboua, T.F. ; Timité-Konan, M. ; Diecket Ahoussou, L. ; Assouan, J.K. ; Sami, M.F. ; Kouadio, S. ; Goka, B. ; Welbeck, J. ; Sackey, A. ; Owiafe, S.N. ; Da Silva, Z.J. ; Paulo, J. ; Rodrigues, A. ; Da Silva, D. ; Medina, C. ; Oliviera-Souto, I. ; Østergaard, L. ; Laursen, A. ; Sodemann, M. ; Aaby, P. ; Fomsgaard, A. ; Erikstrup, C. ; Eugen-Olsen, J. ; Maïga, M.Y. ; Diakité, F.F. ; Kalle, A. ; Katile, D. ; Traore, H.A. ; Minta, D. ; Cissé, T. ; Dembelé, M. ; Doumbia, M. ; Fomba, M. ; Kaya, A.S. ; Traoré, A.M. ; Traoré, H. ; Toure, A.A. ; Dicko, F. ; Sylla, M. ; Berthé, A. ; Traoré, H.C. ; Koïta, A. ; Koné, N. ; N'Diaye, C. ; Coulibaly, S.T. ; Traoré, M. ; Traoré, N. ; Charurat, M. ; Alim, G. ; Dapiap, S. ; Igbinoba, F. ; Benson, O. ; Adebamowo, C. ; James, J. ; Obaseki ; Osakede, P. ; Olasode, J. ; Seydi, M. ; Sow, P.S. ; Diop, B. ; Manga, N.M. ; Tine, J.M. ; Bassabi, C.C. ; Sy, H.S. ; Ba, A. ; Diagne, A. ; Dior, H. ; Faye, M. ; Gueye, R.D. ; Mbaye, A.D. ; Patassi, A. ; Kotosso, A. ; Kariyare, B.G. ; Gbadamassi, G. ; Komi, A. ; Mensah-Zukong, K.E. ; Pakpame, P. ; Koko Lawson-Evi, A. ; Atakouma, Y. ; Takassi, E. ; Djeha, A. ; Ephoévi-gah, A. ; El-Hadj Djibril, S. ; Dabis, F. ; Bissagnene, E. ; Arrivé, E. ; Coffie, P. ; Ekouevi, D. ; Jaquet, A. ; Sasco, A.J. ; Amani, D. ; Azani, J.-C. ; Balestre, E. ; Bessekon, S. ; Bohossou, F. ; Gilbert, C. ; Karcher, S. ; Gonsan, J.M. ; Le Carrou, J. ; Lenaud, S. ; Nchot, C. ; Malateste, K. ; Yao, A.R. ; Siloué, B. ; Clouet, G. ; Dosso, M. ; Doring, A. ; Kouakou, A. ; Rabourdin, E. ; Rivenc, J. ; Anglaret, X. ; Ba, B. ; Essanin, J.B. ; Ciaranello, A. ; Datté, S. ; Desmonde, S. ; Elvis Diby, J.-S. ; Gottlieb, G.S. ; Horo, A.G. ; Kangah, S.N. ; Malvy, D. ; Meless, D. ; Mounkaila-Harouna, A. ; Ndondoki, C. ; Shiboski, C. ; Tchounga, B. ; Thiébaut, R. ; Wandeler, G. ; McGowan, C. ; Cahn, P. ; Gotuzzo, E. ; Wolff, M. ; Grinsztejn, B. ; Pape, J. ; Padgett, D. ; Madero, J.S. | International Union Against Tuberculosis and Lung Disease | 2020-06-10T18:11:32ZSETTING: Drug resistance threatens tuberculosis (TB) control, particularly among human immunodeficiency virus (HIV) infected persons. OBJECTIVE: To describe practices in the prevention and management of drug-resistant TB under antiretroviral the[...]texto impreso
Broger, T. ; Nicol, M.P. ; Sigal, G.B. ; Gotuzzo, E. ; Zimmer, A.J. ; Surtie, S. ; Caceres-Nakiche, T. ; Mantsoki, A. ; Reipold, E.I. ; Székely, R. ; Tsionsky, M. ; van Heerden, J. ; Plisova, T. ; Chikamatsu, K. ; Lowary, T.L. ; Pinter, A. ; Mitarai, S. ; Moreau, E. ; Schumacher, S.G. ; Denkinger, C.M. | American Society for Clinical Investigation | 2020-12-14T16:06:09ZBACKGROUND. Inadequate tuberculosis (TB) diagnostics are a major hurdle in the reduction of disease burden, and accurate point-of-care tests (POCTs) are urgently needed. We assessed the diagnostic accuracy of Fujifilm SILVAMP TB lipoarabinomanna[...]texto impreso
Schwalb, A. ; Pérez-Muto, V. ; Cachay, R. ; Tipismana, M. ; Álvarez, C. ; Mejia, F. ; González-Lagos, E. ; Gotuzzo, E. | MDPI AG | 2020-12-14T16:10:12ZBackground: Vertical transmission of HTLV-1 could lead to the early development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). This significantly affects quality of life and increases morbimortality. Objective: To descri[...]texto impreso
Maco, V. ; Marcos, L. ; Delgado, J. ; Herrera, J. ; Nestares, J. ; Terashima, A. ; Samalvides, F. ; Gotuzzo, E. | Sociedade Brasileira de Medicina Tropical | 2019-04-24T18:23:57ZIntroduction: The therapeutic scheme of triclabendazole (TCBZ), the recommended anthelmintic against Fasciola hepatica, involves 10mg/kg of body weight administered in a single dose; however, clinical trials in children are scarce. We evaluated [...]texto impreso
Acosta, F. ; Agapito, J. ; Cabibbe, A.M. ; Cáceres, T. ; Sola, C. ; Pérez-Lago, L. ; Abascal, E. ; Herranz, M. ; Meza, E. ; Klotoe, B. ; Muñoz, P. ; Rossolini, G.M. ; Bartoloni, A. ; Tortoli, E. ; Cirillo, D.M. ; Gotuzzo, E. ; García De Viedma, D. | Centers for Disease Control and Prevention | 2019-07-04T16:59:34ZWe performed a cross-border molecular epidemiology analysis of multidrug-resistant tuberculosis in Peru, Spain, and Italy. This analysis revealed frequent transmission in Peru and exportation of a strain that recreated similar levels of transmis[...]texto impreso
Shah, L. ; Choi, H. W. ; Berrang-Ford, L. ; Henostroza, G. ; Krapp, F. ; Zamudio, C. ; Heymann, S. J. ; Kaufman, J. S. ; Ciampi, A. ; Seas, C. ; Gotuzzo, E. ; Brewer, T. F. | International Union Against Tuberculosis and Lung Disease | 2020-06-10T18:11:30ZSETTING: Peru reports among the highest multidrug-resistant tuberculosis (MDR-TB) rates in the Americas, with a growing proportion in previously untreated tuberculosis (TB) cases. The identification of clusters of primary MDR-TB compared with dr[...]texto impreso
Cesar, C. ; Koethe, J.R. ; Giganti, M.J. ; Rebeiro, P. ; Althoff, K.N. ; Napravnik, S. ; Mayor, A. ; Grinsztejn, B. ; Wolff, M. ; Padgett, D. ; Sierra Madero, J. ; Gotuzzo, E. ; Sterling, T.R. ; Willig, J. ; Levison, J. ; Kitahata, M. ; Rodriguez-Barradas, M.C. ; Moore, R.D. ; McGowan, C. ; Shepherd, B.E. ; Cahn, P. | Wiley Open Access | 2019-04-24T18:23:55ZIntroduction: Latinos living with HIV in the Americas share a common ethnic and cultural heritage. In North America, Latinos have a relatively high rate of new HIV infections but lower rates of engagement at all stages of the care continuum, whe[...]
