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Título:
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Sedation practices and clinical outcomes in mechanically ventilated patients in a prospective multicenter cohort
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Autores:
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Aragón, R.E. ;
Proaño, A. ;
Mongilardi, N. ;
de Ferrari, A. ;
Herrera, P. ;
Roldan, R. ;
Paz, E. ;
Jaymez, A.A. ;
Chirinos, E. ;
Portugal, J. ;
Quispe, R. ;
Brower, R.G. ;
Checkley, W.
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Tipo de documento:
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texto impreso
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Editorial:
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BMC, 2019-12-06T20:57:46Z
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Nota general:
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info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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Objectives: We sought to study the association between sedation status, medications (benzodiazepines, opioids, and antipsychotics), and clinical outcomes in a resource-limited setting. Design: A longitudinal study of critically ill participants on mechanical ventilation. Setting: Five intensive care units (ICUs) in four public hospitals in Lima, Peru. Patients: One thousand six hundred fifty-seven critically ill participants were assessed daily for sedation status during 28 days and vital status by day 90. Results: After excluding data of participants without a Richmond Agitation Sedation Scale score and without sedation, we followed 1338 (81%) participants longitudinally for 18,645 ICU days. Deep sedation was present in 98% of participants at some point of the study and in 12,942 ICU days. Deep sedation was associated with higher mortality (interquartile odds ratio (OR) = 5.42, 4.23-6.95; p
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En línea:
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http://repositorio.upch.edu.pe/handle/upch/7401
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