Información del autor
Autor Zimic, Mirko |
Documentos disponibles escritos por este autor (38)
Añadir el resultado a su cesta Hacer una sugerencia Refinar búsqueda
texto impreso
Solis, Leonardo ; Coronel, Jorge ; Rueda, Daniel ; Gilman, Robert H. ; Sheen, Patricia ; Zimic, Mirko | Elsevier | 2019-02-06T14:57:42ZTuberculosis (TB) control efforts are hampered by a mismatch in diagnostic technology. Lack of adequate early diagnostics and Multi-drug resistant (MDR) detection is a critical problem in control efforts. Alternate and novel diagnostic approache[...]texto impreso
Pajuelo, Monica J. ; Eguiluz, María ; Roncal, Elisa ; Quiñones-García, Stefany ; Clipman, Steven J. ; Calcina, Juan ; Gavidia, Cesar M. ; Sheen, Patricia ; Garcia, Hector H. ; Gilman, Robert H. ; Gonzalez, Armando E. ; Zimic, Mirko ; Cysticercosis Working Group in Peru | Public Library of Science | 2019-01-25T15:18:36ZThe adult Taenia solium, the pork tapeworm, usually lives as a single worm in the small intestine of humans, its only known definitive host. Mechanisms of genetic variation in T. solium are poorly understood. Using three microsatellite markers p[...]texto impreso
Berthelot, Karine ; Estevez, Yannick ; Quiliano, Miguel ; Baldera-Aguayo, Pedro-A. ; Zimic, Mirko ; Pribat, Anne ; Bakleh, Marc-Elias ; Teyssier, Emeline ; Gallusci, Philippe ; Gardrat, Christian ; Lecomte, Sophie ; Peruch, Frederic | Elsevier | 2019-02-06T14:45:11ZIn this study, we cloned, expressed and purified the isopentenyl diphosphate isomerases (IDIs) from two plants, Hevea brasiliensis and Solanum lycopersicum, and compared them to the already well characterized Escherichia coli IDI. Phylogenetic a[...]texto impreso
Machicado, Claudia ; Marcos, Luis-A. ; Zimic, Mirko | Springer International Publishing | 2019-02-06T14:45:37ZFasciola hepatica is considered an emergent human pathogen, causing liver fibrosis or cirrhosis, conditions that are known to be direct causes of cancer. Some parasites have been categorized by WHO as carcinogenic agents such as Opisthorchis viv[...]texto impreso
Pajuelo, Monica J. ; Eguiluz, María ; Dahlstrom, Eric ; Requena, David ; Guzman, Frank ; Ramírez, Manuel ; Sheen, Patricia ; Frace, Michael ; Sammons, Scott ; Cama, Vitaliano ; Anzick, Sarah ; Bruno, Dan ; Mahanty, Siddhartha ; Wilkins, Patricia ; Nash, Theodore ; Gonzalez, Armando ; Garcia, Hector H. ; Gilman, Robert H. ; Porcella, Steve ; Zimic, Mirko | Public Library of Science | 2019-02-06T14:53:08ZBACKGROUND: Infections with Taenia solium are the most common cause of adult acquired seizures worldwide, and are the leading cause of epilepsy in developing countries. A better understanding of the genetic diversity of T. solium will improve p[...]texto impreso
Best, Ivan ; Privat-Maldonado, Angela ; Cruz, Maria ; Zimic, Mirko ; Bras-Gonçalves, Rachel ; Lemesre, Jean-Loup ; Arevalo, Jorge | Frontiers Media | 2018-10-10T23:27:56ZClinical manifestations of American Tegumentary Leishmaniasis (ATL) include cutaneous (CL) and mucous forms (ML); however, there are asymptomatic individuals who despite being infected do not present any clinical manifestations. This study chara[...]texto impreso
Cangalaya, Carla ; Zimic, Mirko ; Marzal, Miguel ; Gonzalez, Armando E. ; Guerra-Giraldez, Cristina ; Mahanty, Siddhartha ; Nash, Theodore E. ; Garcia, Hector H. | Public Library of Science | 2019-02-06T14:53:09ZBACKGROUND: Neurocysticercosis (NCC), infection of the central nervous system by Taenia solium cysticerci, is a pleomorphic disease. Inflammation around cysticerci is the major cause of disease but is variably present. One factor modulating the[...]texto impreso
Oberhelman, Richard A. ; Huaynate, Cynthia Anticona ; Correa, Malena ; Malpartida, Holger Mayta ; Pajuelo, Monica ; Paz-Soldan, Valerie A. ; Gilman, Robert H. ; Zimic, Mirko ; Murphy, Laura ; Belizan, Jose | American Society of Tropical Medicine and Hygiene | 2019-01-25T17:00:25ZPostdoctoral training programs are usually highly individualized arrangements between trainees and a limited number of senior mentors in their field, an approach that contrasts with current trends in public health education that promote interdis[...]texto impreso
Alva, Alicia ; Cangalaya, Carla ; Quiliano, Miguel ; Krebs, Casey ; Gilman, Robert H. ; Sheen, Patricia ; Zimic, Mirko | Public Library of Science | 2019-01-25T15:28:05ZParasitic infections are generally diagnosed by professionals trained to recognize the morphological characteristics of the eggs in microscopic images of fecal smears. However, this laboratory diagnosis requires medical specialists which are lac[...]texto impreso
Salazar-Salinas, Karim ; Baldera-Aguayo, Pedro A. ; Encomendero-Risco, Jimy J. ; Orihuela, Melvin ; Sheen, Patricia ; Seminario, Jorge M. ; Zimic, Mirko | American Chemical Society | 2020-06-10T18:12:14ZMycobacterium tuberculosis pyrazinamidase (PZAse) is a key enzyme to activate the pro-drug pyrazinamide (PZA). PZAse is a metalloenzyme that coordinates in vitro different divalent metal cofactors in the metal coordination site (MCS). Several m[...]texto impreso
Alcántara, Roberto ; Fuentes, Patricia ; Antiparra, Ricardo ; Santos, Marco ; Gilman, Robert H. ; Kirwan, Daniela E. ; Zimic, Mirko ; Sheen, Patricia | American Society for Microbiology | 2018-11-30T17:17:15ZAlthough pyrazinamide (PZA) is a key component of first and second line tuberculosis treatment regimens, there is no gold standard to determine PZA resistance. Approximately 50% of multidrug-resistant tuberculosis (MDR-TB) and over 90% of extens[...]texto impreso
Ramirez-Salinas, Gema L. ; García-Machorro, J. ; Quiliano, Miguel ; Zimic, Mirko ; Briz, Veronica ; Rojas-Hernandez, Saul ; Correa-Basurto, J. | Springer | 2019-02-06T14:52:40ZThe goal of this study was to identify neuraminidase (NA) residue mutants from human influenza AH1N1 using sequences from 1918 to 2012. Multiple alignment studies of complete NA sequences (5732) were performed. Subsequently, the crystallographic[...]texto impreso
Sheen, Patricia ; Requena, David ; Gushiken, Eduardo ; Gilman, Robert H. ; Antiparra, Ricardo ; Lucero, Bryan ; Lizárraga, Pilar ; Cieza, Basilio ; Roncal, Elisa ; Grandjean, Louis ; Pain, Arnab ; McNerney, Ruth ; Clark, Taane G. ; Moore, David ; Zimic, Mirko | BMC | 2019-01-25T15:02:14ZBACKGROUND: Tuberculosis (TB) is a major global health problem and drug resistance compromises the efforts to control this disease. Pyrazinamide (PZA) is an important drug used in both first and second line treatment regimes. However, its comple[...]texto impreso
Saito, Mayuko ; Goel-Apaza, Sonia ; Espetia, Susan ; Velasquez, Daniel ; Cabrera, Lilia ; Loli, Sebastian ; Crabtree, Jean E. ; Black, Robert E. ; Kosek, Margaret ; Checkley, William ; Zimic, Mirko ; Bern, Caryn ; Cama, Vitaliano ; Gilman, Robert H. | Oxford University Press | 2020-06-10T18:11:32ZBACKGROUND: Human noroviruses are among the most common enteropathogens globally, and are a leading cause of infant diarrhea in developing countries. However, data measuring the impact of norovirus at the community level are sparse. METHODS: We [...]texto impreso
Ponce, Reynaldo ; León-Janampa, Nancy ; Gilman, Robert H. ; Liendo, Ruddy ; Roncal, Elisa ; Luis, Sueline ; Quiñones-García, Stefany ; Silverstein, Zach ; Garcia, Hector H. ; Gonzales, Armando ; Sheen, Patricia ; Zimic, Mirko ; Pajuelo, Monica J. ; Cysticercosis Working Group in Peru | Elsevier | 2018-11-30T02:09:28ZCysticercosis is a worldwide parasitic disease of humans and pigs principally caused by infection with the larvae of the pork tapeworm Taenia solium. Through the use of the recently-made-available T. solium genome, we identified a gene within a [...]