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Alroy, Karen A. ; Arroyo, Gianfranco ; Gilman, Robert H. ; Gonzales-Gustavson, Eloy ; Gallegos, Linda ; Gavidia, Cesar M. ; Verastegui, Manuela ; Rodriguez, Silvia ; López, Teresa ; Gomez-Puerta, Luis A. ; Alroy, Joseph ; Garcia, Hector H. ; Gonzalez, Armando E. ; Cysticercosis Working Group in Peru | American Society of Tropical Medicine and Hygiene | 2018-11-30T02:09:30ZNeurocysticercosis (NCC), the infection of the human central nervous system (CNS) with larval cysts of Taenia solium causes widespread neurological morbidity. Animal models are crucial for studying the pathophysiology and treatment of NCC. Some [...]texto impreso
Jara, Luis M. ; Rodriguez, Magaly ; Altamirano, Faride ; Herrera, Antonio ; Verastegui, Manuela ; Gimenez-Lirola, Luis G. ; Gilman, Robert H. ; Gavidia, Cesar M. | American Society of Tropical Medicine and Hygiene | 2019-07-04T16:59:29ZCystic echinococcosis (CE) is a parasitic zoonosis caused by the larval stage of the tapeworm Echinococcus granulosus. Detection of the adult stage in the canine definitive host is essential for estimating infection rates, surveillance and monit[...]texto impreso
Yauri, Veronica ; Castro-Sesquen, Yagahira E. ; Verastegui, Manuela ; Angulo, Noelia ; Recuenco, Fernando ; Cabello, Ines ; Malaga, Edith ; Bern, Caryn ; Gavidia, Cesar M. ; Gilman, Robert H. | American Society of Tropical Medicine and Hygiene | 2019-02-06T14:48:08ZPigs were infected with a Bolivian strain of Trypanosoma cruzi (genotype I) and evaluated up to 150 days postinoculation (dpi) to determine the use of pigs as an animal model of Chagas disease. Parasitemia was observed in the infected pigs durin[...]texto impreso
Liu, Xiaofang ; Jahuira, Helena ; Gilman, Robert H. ; Alva, Alicia ; Cabrera, Lilia ; Okamoto, Michiko ; Xu, Hang ; Windle, Henry J. ; Kelleher, Dermot ; Varela, Marco ; Verastegui, Manuela ; Calderón, Maritza ; Sanchez, Gerardo ; Sarabia, Vanessa ; Ballard, Sarah B. ; Bern, Caryn ; Mayta, Holger ; Crabtree, Jean E. ; Cama, Vitaliano ; Saito, Mayuko ; Oshitani, Hitoshi | American Society for Microbiology | 2019-02-06T14:45:36ZHuman sapovirus has been shown to be one of the most important etiologies in pediatric patients with acute diarrhea. However, very limited data are available about the causative roles and epidemiology of sapovirus in community settings. A nest[...]texto impreso
Shah, Vishal ; Ferrufino, Lisbeth ; Gilman, Robert H. ; Ramirez, Margot ; Saenza, Eliana ; Malaga, Edith ; Sanchez, Gerardo ; Okamoto, Emi E. ; Sherbuck, Jacqueline E. ; Clark, Eva H. ; Galdos-Cardenas, Gerson ; Bozo, Ricardo ; Flores-Franco, Jorge Luis ; Colanzi, Rony ; Verastegui, Manuela ; Bern, Caryn | American Society for Microbiology | 2020-06-10T18:11:30ZTrypanosoma cruzi causes Chagas disease, which affects an estimated 7 million to 8 million people. Chagas disease is endemic throughout Latin America, with the highest prevalence in Bolivia. Conventional diagnosis requires a well-equipped labor[...]texto impreso
Mayta, Holger ; Romero, Yomara K. ; Pando, Alejandra ; Verastegui, Manuela ; Tinajeros, Freddy ; Bozo, Ricardo ; Henderson-Frost, Josephine ; Colanzi, Rony ; Flores, Jorge ; Lerner, Richard ; Bern, Caryn ; Gilman, Robert H. | Public Library of Science | 2019-07-04T17:00:16ZBACKGROUND: The detection of Trypanosoma cruzi genetic material in clinical samples is considered an important diagnostic tool for Chagas disease. We have previously demonstrated that PCR using clot samples yields greater sensitivity than either[...]texto impreso
Chile, Nancy ; Clark, Taryn ; Arana, Yanina ; Ortega, Ynes R. ; Palma, Sandra ; Mejia, Alan ; Angulo, Noelia ; Kosek, Jon C. ; Kosek, Margaret ; Gomez-Puerta, Luis A. ; Garcia, Hector H. ; Gavidia, Cesar M. ; Gilman, Robert H. ; Verastegui, Manuela | Public Library of Science | 2019-02-06T14:45:12ZBACKGROUND: The transitional period between the oncosphere and the cysticercus of Taenia solium is the postoncospheral (PO) form, which has not yet been completely characterized. The aim of this work was to standardize a method to obtain T. soli[...]texto impreso
Martin, Diana L. ; Marks, Morgan ; Galdos-Cardenas, Gerson ; Gilman, Robert H. ; Goodhew, Brook ; Ferrufino, Lisbeth ; Halperin, Anthony ; Sanchez, Gerardo ; Verastegui, Manuela ; Escalante, Patricia ; Náquira, César ; Levy, Michael Z. ; Bern, Caryn | American Society of Tropical Medicine and Hygiene | 2020-06-10T18:11:31ZChagas disease, caused by the protozoan parasite Trypanosoma cruzi, is a major cause of morbidity and mortality in Central and South America. Geographic variations in the sensitivity of serologic diagnostic assays to T. cruzi may reflect differe[...]texto impreso
Kaplinski, Michelle ; Jois, Malasa ; Galdos-Cardenas, Gerson ; Rendell, Victoria R. ; Shah, Vishal ; Do, Rose Q. ; Marcus, Rachel ; Pena, Melissa S. Burroughs ; Abastoflor, Maria Del Carmen ; LaFuente, Carlos ; Bozo, Ricardo ; Valencia, Edward ; Verastegui, Manuela ; Colanzi, Rony ; Gilman, Robert H. ; Bern, Caryn | Oxford University Press | 2019-02-06T14:52:17ZBACKGROUND: We studied women and their infants to evaluate risk factors for congenital transmission and cardiomyopathy in Trypanosoma cruzi-infected women. METHODS: Women provided data and blood for serology and quantitative polymerase chain rea[...]texto impreso
Messenger, Louisa A. ; Gilman, Robert H. ; Verastegui, Manuela ; Galdos-Cardenas, Gerson ; Sanchez, Gerardo ; Valencia, Edward ; Sanchez, Leny ; Malaga, Edith ; Rendell, Victoria R. ; Jois, Malasa ; Shah, Vishal ; Santos, Nicole ; Abastoflor, Maria Del Carmen ; LaFuente, Carlos ; Colanzi, Rony ; Bozo, Ricardo ; Bern, Caryn | Oxford University Press | 2019-01-25T16:03:22ZBackground: Congenital Trypanosoma cruzi transmission is now estimated to account for 22% of new infections, representing a significant public health problem across Latin America and internationally. Treatment during infancy is highly efficaciou[...]texto impreso
Rendell, Victoria R. ; Gilman, Robert H. ; Valencia, Edward ; Galdos-Cardenas, Gerson ; Verastegui, Manuela ; Sanchez, Leny ; Acosta, Janet ; Sanchez, Gerardo ; Ferrufino, Lisbeth ; LaFuente, Carlos ; Abastoflor, Maria Del Carmen ; Colanzi, Rony ; Bern, Caryn | Public Library of Science | 2019-02-06T14:53:12ZBACKGROUND: Congenital transmission is a major source of new Trypanosoma cruzi infections, and as vector and blood bank control continue to improve, the proportion due to congenital infection will grow. A major unanswered question is why report[...]
