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Autor Mahanty, Siddhartha |
Documentos disponibles escritos por este autor (9)
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Paredes, Adriana ; Saenz, Patricia ; Marzal, Miguel-W. ; Orrego, Miguel-A. ; Castillo, Yesenia ; Rivera, Andrea ; Mahanty, Siddhartha ; Guerra-Giraldez, Cristina ; Garcia, Hector-H. ; Nash, Theodore-E. | Elsevier | 2019-02-06T14:45:57ZNeurocysticercosis (NCC), an infection of the brain by Taenia solium (Ts) cysts, is the most common cause of adult-onset epilepsy in developing countries. Serological testing consists primarily of varying methods to detect antibodies in body fl[...]texto impreso
Tuero, Iskra ; Palma, Sandra ; Cabeza, Franco ; Saleemi, Sarah ; Rodriguez, Silvia ; Gonzales, Isidro ; Mayta, Holger ; Mahanty, Siddhartha ; Garcia, Hector H. ; Gilman, Robert H. | Public Library of Science | 2019-02-06T14:53:09ZBACKGROUND: The ability of Taenia solium to modulate the immune system likely contributes to their longevity in the human host. We tested the hypothesis that the nature of the immune response is related to the location of parasite and clinical m[...]texto impreso
Marzal, Miguel ; Guerra-Giraldez, Cristina ; Paredes, Adriana ; Cangalaya, Carla ; Rivera, Andrea ; Gonzalez, Armando E. ; Mahanty, Siddhartha ; Garcia, Hector H. ; Nash, Theodore E. | Public Library of Science | 2020-06-10T18:12:17ZCysticidal drug treatment of viable Taenia solium brain parenchymal cysts leads to an acute pericystic host inflammatory response and blood brain barrier breakdown (BBB), commonly resulting in seizures. Naturally infected pigs, untreated or trea[...]texto impreso
Pajuelo, Monica J. ; Eguiluz, María ; Dahlstrom, Eric ; Requena, David ; Guzman, Frank ; Ramírez, Manuel ; Sheen, Patricia ; Frace, Michael ; Sammons, Scott ; Cama, Vitaliano ; Anzick, Sarah ; Bruno, Dan ; Mahanty, Siddhartha ; Wilkins, Patricia ; Nash, Theodore ; Gonzalez, Armando ; Garcia, Hector H. ; Gilman, Robert H. ; Porcella, Steve ; Zimic, Mirko | Public Library of Science | 2019-02-06T14:53:08ZBACKGROUND: Infections with Taenia solium are the most common cause of adult acquired seizures worldwide, and are the leading cause of epilepsy in developing countries. A better understanding of the genetic diversity of T. solium will improve p[...]texto impreso
Cangalaya, Carla ; Zimic, Mirko ; Marzal, Miguel ; Gonzalez, Armando E. ; Guerra-Giraldez, Cristina ; Mahanty, Siddhartha ; Nash, Theodore E. ; Garcia, Hector H. | Public Library of Science | 2019-02-06T14:53:09ZBACKGROUND: Neurocysticercosis (NCC), infection of the central nervous system by Taenia solium cysticerci, is a pleomorphic disease. Inflammation around cysticerci is the major cause of disease but is variably present. One factor modulating the[...]texto impreso
Cangalaya, Carla ; Bustos, Javier-A. ; Calcina, Juan ; Vargas-Calla, Ana ; Suarez, Diego ; Gonzalez, Armando-E. ; Chacaltana, Juan ; Guerra-Giraldez, Cristina ; Mahanty, Siddhartha ; Nash, Theodore-E. ; Garcia, Hector-H. | Public Library of Science | 2019-02-06T14:45:11ZBACKGROUND: Disease manifestations in neurocysticercosis (NCC) are frequently due to inflammation of degenerating Taenia solium brain cysts. Exacerbated inflammation post anthelmintic treatment is associated with leakage of the blood brain barr[...]texto impreso
Mahanty, Siddhartha ; Orrego, Miguel Angel ; Mayta, Holger ; Marzal, Miguel ; Cangalaya, Carla ; Paredes, Adriana ; Gonzales-Gustavson, Eloy ; Arroyo, Gianfranco ; Gonzalez, Armando E. ; Guerra-Giraldez, Cristina ; Garcia, Hector H. ; Nash, Theodore E. | Public Library of Science | 2019-02-06T14:53:10ZCysticidal treatment of neurocysticercosis, an infection of humans and pig brains with Taenia solium, results in an early inflammatory response directed to cysts causing seizures and focal neurological manifestations. Treatment-induced pericysti[...]texto impreso
Cangalaya, Carla ; Bustos, Javier A. ; Calcina, Juan ; Vargas-Calla, Ana ; Mamani, Javier ; Suarez, Diego ; Arroyo, Gianfranco ; Gonzalez, Armando E. ; Chacaltana, Juan ; Guerra-Giraldez, Cristina ; Mahanty, Siddhartha ; Nash, Theodore E. ; Garcia, Hector H. | Public Library of Science | 2019-01-25T16:03:19ZBACKGROUND: The onset of anthelmintic treatment of neurocysticercosis (NCC) provokes an acute immune response of the host, which in human cases is associated with exacerbation of neurological symptoms. This inflammation can occur at the first da[...]texto impreso
Mahanty, Siddhartha ; Orrego, Miguel A. ; Cangalaya, Carla ; Adrianzen, M. Paz ; Arroyo, Gianfranco ; Calcina, Juan ; Gonzalez, Armando E. ; Garcia, Hector H. ; Guerra-Giraldez, Cristina ; Nash, Theodore E. ; Cysticercosis Working Group in Peru | Public Library of Science | 2019-01-25T16:03:22ZBACKGROUND: Neurocysticercosis (NCC) is an infection of the brain with the larval cyst of the tapeworm, Taenia solium. Cysticidal treatment induces parasite killing resulting in a post inflammatory response and seizures, which generally requires[...]