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Paredes, Adriana ; Saenz, Patricia ; Marzal, Miguel-W. ; Orrego, Miguel-A. ; Castillo, Yesenia ; Rivera, Andrea ; Mahanty, Siddhartha ; Guerra-Giraldez, Cristina ; Garcia, Hector-H. ; Nash, Theodore-E. | Elsevier | 2019-02-06T14:45:57ZNeurocysticercosis (NCC), an infection of the brain by Taenia solium (Ts) cysts, is the most common cause of adult-onset epilepsy in developing countries. Serological testing consists primarily of varying methods to detect antibodies in body fl[...]texto impreso
Marzal, Miguel ; Guerra-Giraldez, Cristina ; Paredes, Adriana ; Cangalaya, Carla ; Rivera, Andrea ; Gonzalez, Armando E. ; Mahanty, Siddhartha ; Garcia, Hector H. ; Nash, Theodore E. | Public Library of Science | 2020-06-10T18:12:17ZCysticidal drug treatment of viable Taenia solium brain parenchymal cysts leads to an acute pericystic host inflammatory response and blood brain barrier breakdown (BBB), commonly resulting in seizures. Naturally infected pigs, untreated or trea[...]texto impreso
Bermudez, Daniela ; Azad, Priti ; Figueroa-Mujíca, Rómulo ; Vizcardo-Galindo, Gustavo ; Corante, Noemi ; Guerra-Giraldez, Cristina ; Haddad, Gabriel G. ; Villafuerte, Francisco C. | American Physiological Society | 2020-07-14T00:00:56ZExcessive erythrocytosis (EE) is the main sign of chronic mountain sickness (CMS), a maladaptive clinical syndrome prevalent in Andean and other high-altitude populations worldwide. The pathophysiological mechanism of EE is still controversial, [...]texto impreso
Bermudez, Daniela ; Azad, Priti ; Figueroa-Mujíca, Rómulo ; Vizcardo-Galindo, Gustavo ; Corante, Noemi ; Guerra-Giraldez, Cristina ; Haddad, Gabriel G. ; Villafuerte, Francisco C. | American Physiological Society | 2019-12-06T20:57:40ZExcessive erythrocytosis (EE) is the main sign of Chronic Mountain Sickness (CMS), a maladaptive clinical syndrome prevalent in Andean and other high-altitude populations worldwide. The pathophysiological mechanism of EE is still controversial, [...]texto impreso
Cangalaya, Carla ; Zimic, Mirko ; Marzal, Miguel ; Gonzalez, Armando E. ; Guerra-Giraldez, Cristina ; Mahanty, Siddhartha ; Nash, Theodore E. ; Garcia, Hector H. | Public Library of Science | 2019-02-06T14:53:09ZBACKGROUND: Neurocysticercosis (NCC), infection of the central nervous system by Taenia solium cysticerci, is a pleomorphic disease. Inflammation around cysticerci is the major cause of disease but is variably present. One factor modulating the[...]texto impreso
Gutierrez-Loli, Renzo ; Orrego, Miguel A. ; Sevillano-Quispe, Oscar G. ; Herrera-Arrasco, Luis ; Guerra-Giraldez, Cristina | Frontiers Media | 2019-01-25T17:00:26ZMicroRNAs (miRNAs) are short, endogenous, non-coding, single-stranded RNAs involved in post-transcriptional gene regulation. Although, several miRNAs have been identified in parasitic helminths, there is little information about their identifica[...]texto impreso
Cangalaya, Carla ; Bustos, Javier-A. ; Calcina, Juan ; Vargas-Calla, Ana ; Suarez, Diego ; Gonzalez, Armando-E. ; Chacaltana, Juan ; Guerra-Giraldez, Cristina ; Mahanty, Siddhartha ; Nash, Theodore-E. ; Garcia, Hector-H. | Public Library of Science | 2019-02-06T14:45:11ZBACKGROUND: Disease manifestations in neurocysticercosis (NCC) are frequently due to inflammation of degenerating Taenia solium brain cysts. Exacerbated inflammation post anthelmintic treatment is associated with leakage of the blood brain barr[...]texto impreso
Mahanty, Siddhartha ; Orrego, Miguel Angel ; Mayta, Holger ; Marzal, Miguel ; Cangalaya, Carla ; Paredes, Adriana ; Gonzales-Gustavson, Eloy ; Arroyo, Gianfranco ; Gonzalez, Armando E. ; Guerra-Giraldez, Cristina ; Garcia, Hector H. ; Nash, Theodore E. | Public Library of Science | 2019-02-06T14:53:10ZCysticidal treatment of neurocysticercosis, an infection of humans and pig brains with Taenia solium, results in an early inflammatory response directed to cysts causing seizures and focal neurological manifestations. Treatment-induced pericysti[...]texto impreso
Cangalaya, Carla ; Bustos, Javier A. ; Calcina, Juan ; Vargas-Calla, Ana ; Mamani, Javier ; Suarez, Diego ; Arroyo, Gianfranco ; Gonzalez, Armando E. ; Chacaltana, Juan ; Guerra-Giraldez, Cristina ; Mahanty, Siddhartha ; Nash, Theodore E. ; Garcia, Hector H. | Public Library of Science | 2019-01-25T16:03:19ZBACKGROUND: The onset of anthelmintic treatment of neurocysticercosis (NCC) provokes an acute immune response of the host, which in human cases is associated with exacerbation of neurological symptoms. This inflammation can occur at the first da[...]texto impreso
Mahanty, Siddhartha ; Orrego, Miguel A. ; Cangalaya, Carla ; Adrianzen, M. Paz ; Arroyo, Gianfranco ; Calcina, Juan ; Gonzalez, Armando E. ; Garcia, Hector H. ; Guerra-Giraldez, Cristina ; Nash, Theodore E. ; Cysticercosis Working Group in Peru | Public Library of Science | 2019-01-25T16:03:22ZBACKGROUND: Neurocysticercosis (NCC) is an infection of the brain with the larval cyst of the tapeworm, Taenia solium. Cysticidal treatment induces parasite killing resulting in a post inflammatory response and seizures, which generally requires[...]
