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Ong, Catherine W. M. ; Elkington, Paul T. ; Brilha, Sara ; Ugarte-Gil, Cesar ; Tome-Esteban, Maite T. ; Tezera, Liku B. ; Pabisiak, Przemyslaw J. ; Moores, Rachel C. ; Sathyamoorthy, Tarangini ; Patel, Vimal ; Gilman, Robert H. ; Porter, Joanna C. ; Friedland, Jon S. | Public Library of Science | 2019-02-06T14:53:12ZPulmonary cavities, the hallmark of tuberculosis (TB), are characterized by high mycobacterial load and perpetuate the spread of M. tuberculosis. The mechanism of matrix destruction resulting in cavitation is not well defined. Neutrophils are e[...]texto impreso
Fox, Katharine A. ; Kirwan, Daniela E. ; Whittington, Ashley M. ; Krishnan, Nitya ; Robertson, Brian D. ; Gilman, Robert H. ; López, José W. ; Singh, Shivani ; Porter, Joanna C. ; Friedland, Jon S. | American Thoracic Society | 2018-11-30T22:50:35ZRATIONALE: Platelets may interact with the immune system in tuberculosis (TB) to regulate human inflammatory responses that lead to morbidity and spread of infection. OBJECTIVES: To identify a functional role of platelets in the innate inflammat[...]
