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Brito, Julio ; Siques, Patricia ; Arribas, Silvia M. ; Lopez de Pablo, Angel L. ; Gonzalez, M. Carmen ; Naveas, Nelson ; Arriaza, Karem ; Flores, Karen ; Leon-Velarde, Fabiola ; Pulido, Ruth ; Ordenes, Stefany ; Lopez, M. Rosario | Hindawi Publishing Corporation | 2019-02-06T14:52:14ZLong-term chronic intermittent exposure to altitude hypoxia is a labor phenomenon requiring further research. Using a rat model, we examined whether this type of exposure differed from chronic exposure in terms of pulmonary artery remodeling and[...]texto impreso
Lueneburg, Nicole ; Siques, Patricia ; Brito, Julio ; Arriaza, Karem ; Pena, Eduardo ; Klose, Hans ; Leon-Velarde, Fabiola ; Boeger, Rainer H. | Hindawi Publishing Corporation | 2019-02-22T14:54:33ZChronic intermittent hypoxia (CIH) and chronic hypoxia (CH) are associated with high-altitude pulmonary hypertension (HAPH). Asymmetric dimethylarginine (ADMA), a NO synthase (NOS) inhibitor, may contribute to HAPH. This study assessed changes i[...]texto impreso
Siques, Patricia ; Brito, Julio ; Flores, Karen ; Ordenes, Stefany ; Arriaza, Karem ; Pena, Eduardo ; Leon-Velarde, Fabiola ; Lopez de Pablo, Angel L. ; Gonzalez, M. C. ; Arribas, Silvia | Frontiers Media | 2018-12-01T00:04:14ZBackground: In chronic hypoxia (CH) and short-term chronic intermittent hypoxia (CIH) exposure, glycemia and insulin levels decrease and insulin sensitivity increases, which can be explained by changes in glucose transport at skeletal muscles in[...]texto impreso
Siques, Patricia ; Lopez de Pablo, Angel Luis ; Brito, Julio ; Arribas, Silvia M. ; Flores, Karen ; Arriaza, Karem ; Naveas, Nelson ; Gonzalez, M. Carmen ; Hoorntje, Alexander ; Leon-Velarde, Fabiola ; Lopez, M. Rosario | Hindawi Publishing Corporation | 2020-06-10T18:11:33ZWork at high altitude in shifts exposes humans to a new form of chronic intermittent hypoxia, with still unknown health consequences. We have established a rat model resembling this situation, which develops a milder form of right ventricular hy[...]
