|
Título:
|
Household clustering of SARS-CoV-2 in community settings: A study from rural ecuador
|
|
Autores:
|
Del Brutto, O.H. ;
Costa, A.F. ;
Mera, R.M. ;
Recalde, B.Y. ;
Bustos, J.A. ;
Garcia, H.H.
|
|
Tipo de documento:
|
texto impreso
|
|
Editorial:
|
American Society of Tropical Medicine and Hygiene, 2020-12-14T16:06:19Z
|
|
Nota general:
|
info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
|
|
Idiomas:
|
Inglés
|
|
Palabras clave:
|
Editados por otras instituciones
,
Artículos
,
Artículos en revistas indizadas
|
|
Resumen:
|
The SARS-CoV-2 pandemic is now expanding into the developing world with devastating consequences. Departing from a population-based study in rural Ecuador where all adult individuals (aged 40 years or older) were tested for SARS-CoV-2 IgG and IgM antibodies, we expanded it to include a house-based case–control component assessing in-house clustering and other variables potentially associated with infection. We selected houses where exactly two study participants lived and were both seropositive (case-houses), and matched 1:1 to control-houses where both were seronegative. Younger household members had an antibody test performed. Infected household members were found in 33 (92%) case-houses and in only six (17%) control-houses. In 28/29 discordant house pairs, the case-house had seropositive household members and the control-house did not (odds ratio: 28; 95% CI: 4.6–1,144). Our data demonstrate strong in-house clustering of infection in community settings, stressing the importance of early case ascertainment and isolation for SARS-CoV-2 control. Copyright © 2020 by The American Society of Tropical Medicine and Hygiene
|
|
En línea:
|
http://repositorio.upch.edu.pe/handle/upch/8697
|
