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Arroyo, Gianfranco ; Bustos, Javier A. ; Lescano, Andres G. ; Gonzales, Isidro ; Saavedra, Herbert ; Rodriguez, Silvia ; Pretell, E. Javier ; Bonato, Pierina S. ; Lanchote, Vera L. ; Takayanagui, Osvaldo M. ; Horton, John ; Gonzalez, Armando E. ; Gilman, Robert H. ; Garcia, Hector H. | Oxford University Press | 2019-07-04T16:59:18ZBackground: Albendazole is the drug of choice for the treatment of parenchymal neurocysticercosis, although its efficacy is suboptimal. Plasma levels of albendazole sulfoxide (ASOX), the active metabolite of albendazole, are highly variable amon[...]texto impreso
Arroyo, Gianfranco ; Bustos, Javier A. ; Lescano, Andres G. ; Gonzales, Isidro ; Saavedra, Herbert ; Rodriguez, Silvia ; Pretell, E. Javier ; Bonato, Pierina S. ; Lanchote, Vera L. ; Takayanagui, Osvaldo M. ; Horton, John ; Gonzalez, Armando E. ; Gilman, Robert H. ; Garcia, Hector H. | Oxford University Press | 2019-12-06T21:02:55ZBACKGROUND: The efficacy of albendazole therapy in patients with parenchymal neurocysticercosis (NCC) is suboptimal. Plasma levels of albendazole sulfoxide (ASOX), the active metabolite of albendazole, are highly variable among patients. We hypo[...]texto impreso
Arroyo, Gianfranco ; Rodriguez, Silvia ; Lescano, Andres G. ; Alroy, Karen A. ; Bustos, Javier A. ; Santivañez, Saul ; Gonzales, Isidro ; Saavedra, Herbert ; Pretell, E. Javier ; Gonzalez, Armando E. ; Gilman, Robert H. ; Tsang, Victor C. W. ; Garcia, Hector H. ; Cysticercosis Working Group in Peru | Oxford University Press | 2018-11-30T02:09:29ZBackground: The enzyme-linked immunoelectrotransfer blot (EITB) assay is the reference serological test for neurocysticercosis (NCC). A positive result on EITB does not always correlate with the presence of active infections in the central nervo[...]texto impreso
Duque, Kevin R. ; Escalaya, Alejandro L. ; Zapata, Willy ; Burneo, Jorge G. ; Bustos, Javier A. ; Gonzales, Isidro ; Saavedra, Herbert ; Pretell, E. Javier ; Garcia, Hector H. ; Cysticercosis Working Group in Peru | Elsevier | 2018-11-30T02:09:31ZOBJECTIVE: Discordances between imaging findings of parenchymal neurocysticercosis and seizure expression have been reported, and as such the possibility that neurocysticercosis and seizures may frequently coexist by chance has been raised. In t[...]texto impreso
Garcia, Hector H. ; Gonzales, Isidro ; Bustos, Javier A. ; Saavedra, Herbert ; Gavidia, Martin ; Rodriguez, Lourdes ; Najar, Enrique ; Umeres, Hugo ; Pretell, E. Javier | Elsevier | 2019-02-06T14:59:07Ztexto impreso
Tuero, Iskra ; Palma, Sandra ; Cabeza, Franco ; Saleemi, Sarah ; Rodriguez, Silvia ; Gonzales, Isidro ; Mayta, Holger ; Mahanty, Siddhartha ; Garcia, Hector H. ; Gilman, Robert H. | Public Library of Science | 2019-02-06T14:53:09ZBACKGROUND: The ability of Taenia solium to modulate the immune system likely contributes to their longevity in the human host. We tested the hypothesis that the nature of the immune response is related to the location of parasite and clinical m[...]texto impreso
Garcia, Hector H. ; Lescano, Andres G. ; Gonzales, Isidro ; Bustos, Javier A. ; Pretell, E. Javier ; Horton, John ; Saavedra, Herbert ; Gonzalez, Armando E. ; Gilman, Robert H. | Oxford University Press | 2019-02-06T14:45:34ZBACKGROUND: The efficacy of current antiparasitic treatment for cerebral Taenia solium cysticercosis with either albendazole (ABZ) or praziquantel (PZQ) is suboptimal. A recent study demonstrated that combining these 2 antiparasitic drugs improv[...]texto impreso
Toribio, Luz ; Romano, Miryam ; Scott, Alan L. ; Gonzales, Isidro ; Saavedra, Herbert ; Garcia, Hector H. ; Shiff, Clive ; Cysticercosis Working Group in Peru | American Society of Tropical Medicine and Hygiene | 2019-07-04T16:59:28ZNeurocysticercosis (NCC), caused by Taenia solium larvae that reside in the central nervous system, results in serious public health and medical issues in many regions of the world. Current diagnosis of NCC is complex requiring both serology and[...]texto impreso
Garcia, Hector H. ; Gonzales, Isidro ; Lescano, Andres G. ; Bustos, Javier A. ; Zimic, Mirko ; Escalante, Diego ; Saavedra, Herbert ; Gavidia, Martin ; Rodriguez, Lourdes ; Najar, Enrique ; Umeres, Hugo ; Pretell, E. Javier | Elsevier | 2020-06-10T18:12:14ZBACKGROUND: Neurocysticercosis causes a substantial burden of seizure disorders worldwide. Treatment with either praziquantel or albendazole has suboptimum efficacy. We aimed to establish whether combination of these drugs would increase cystici[...]texto impreso
Bustos, Javier A. ; Arroyo, Gianfranco ; Gilman, Robert H. ; Soto-Becerra, Percy ; Gonzales, Isidro ; Saavedra, Herbert ; Pretell, E. Javier ; Nash, Theodore E. ; O'Neal, Seth E. ; Del Brutto, Oscar H. ; Gonzalez, Armando E. ; Garcia, Hector H. ; Cysticercosis Working Group in Peru | Oxford University Press | 2020-07-14T00:00:59ZBACKGROUND: Neurocysticercosis (NCC) is a major cause of acquired epilepsy in most of the world. Larval cysts in the human brain eventually resolve and either disappear or leave a calcified scar that is associated with seizures. This study asses[...]texto impreso
Herrick, Jesica A. ; Maharathi, Biswajit ; Kim, Jin Suh ; Abundis, Gerardo G. ; Garg, Anjali ; Gonzales, Isidro ; Saavedra, Herbert ; Bustos, Javier A. ; Garcia, Hector H. ; Loeb, Jeffrey A. ; Cysticercosis Working Group in Peru | Wiley | 2018-11-30T17:17:14ZObjective: We conducted a retrospective, case-control study of neurocysticercosis patients to ascertain early markers that identify subjects likely to develop treatment-resistant seizures. Methods: Clinical histories and imaging studies from 38 [...]texto impreso
Garcia, Hector H. ; Castillo, Yesenia ; Gonzales, Isidro ; Bustos, Javier A. ; Saavedra, Herbert ; Jacob, Louis ; Del Brutto, Oscar H. ; Wilkins, Patricia P. ; Gonzalez, Armando E. ; Gilman, Robert H. ; Cysticercosis Working Group in Peru | Wiley | 2018-11-30T17:17:15ZOBJECTIVE: To evaluate the diagnostic performance of two commercially available ELISA kits, Novalisa® and Ridascreen® , for the detection of antibodies to Taenia solium, compared to serological diagnosis of neurocysticercosis (NCC) by LLGP-EITB [...]texto impreso
Meneses Quiroz, Luis Jean Pierre ; Gonzales, Isidro ; Pretell, Edwin Javier ; Saavedra, Herbert ; Garcia, Hector H. | American Academy of Neurology | 2019-02-06T14:59:07ZNeurocysticercosis is the infection of the CNS by cysts (larvae) of Taenia solium, a worldwide tropical disease. Cysticercosis lesions frequently locate in the gray-white matter border of the cerebral hemispheres but also occur in other neuroana[...]
