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Documentos disponibles de esta editorial (243)
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Benavides, J.A. ; Velasco-Villa, A. ; Godino, L.C. ; Satheshkumar, P.S. ; Ruby, N. ; Rojas-Paniagua, E. ; Shiva, C. ; Falcón, N. ; Streicker, D.G. | Public Library of Science | 2020-12-14T16:06:07ZRabies virus infections normally cause universally lethal encephalitis across mammals. However, ‘abortive infections’ which are resolved prior to the onset of lethal disease have been described in bats and a variety of non-reservoir species. Her[...]![]()
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Fernandez-Arias, Marta ; Acuna-Villaorduna, Ana ; Miranda, J. Jaime ; Diez-Canseco, Francisco ; Malaga, German | Public Library of Science | 2020-06-10T18:12:20ZOBJECTIVE: To characterize adherence to pharmacological medication and beliefs towards medication in a group of patients with hypertension in a large national hospital. MATERIALS AND METHODS: Cross-sectional survey among patients with hypertensi[...]![]()
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Ruiz-Linares, Andrés ; Adhikari, Kaustubh ; Acuna-Alonzo, Victor ; Quinto-Sanchez, Mirsha ; Jaramillo, Claudia ; Arias, William ; Fuentes, Macarena ; Pizarro, Maria ; Everardo, Paola ; de Avila, Francisco ; Gomez-Valdes, Jorge ; Leon-Mimila, Paola ; Hunemeier, Tabita ; Ramallo, Virginia ; Silva de Cerqueira, Caio C. ; Burley, Mari-Wyn ; Konca, Esra ; de Oliveira, Marcelo Zagonel ; Veronez, Mauricio Roberto ; Rubio-Codina, Marta ; Attanasio, Orazio ; Gibbon, Sahra ; Ray, Nicolas ; Gallo, Carla ; Poletti, Giovanni ; Rosique, Javier ; Schuler-Faccini, Lavinia ; Salzano, Francisco M. ; Bortolini, Maria-Cátira ; Canizales-Quinteros, Samuel ; Rothhammer, Francisco ; Bedoya, Gabriel ; Balding, David ; González-José, Rolando | Public Library of Science | 2020-06-10T18:12:16ZThe current genetic makeup of Latin America has been shaped by a history of extensive admixture between Africans, Europeans and Native Americans, a process taking place within the context of extensive geographic and social stratification. We est[...]![]()
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Accinelli, Roberto Alfonso ; Leon-Abarca, Juan Alonso | Public Library of Science | 2020-07-14T00:00:52ZBACKGROUND: A Demographic and Family Health Survey (ENDES, for Encuesta Demografica y de Salud Familiar in Spanish) is carried out annually in Peru. Based on it, the anemia prevalence was 43.6% in 2016 and 43.8% in 2017 using the WHO cutoff valu[...]![]()
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Ramos-Sono, D. ; Laureano, R. ; Rueda, D. ; Gilman, R.H. ; Rosa, A.L. ; Ruiz, J. ; León, R. ; Sheen, P. ; Zimic, M. | Public Library of Science | 2020-12-14T16:10:06ZTuberculosis (TB) is a major global public health problem with high mortality and morbidity. In low-middle income countries (LMIC) a large number of respiratory symptomatic cases that require TB screening per year demands more accurate, fast and[...]![]()
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Saldarriaga, Omar-A. ; Castellanos-Gonzalez, Alejandro ; Porrozzi, Renato ; Baldeviano, Gerald-C. ; Lescano, Andres-G. ; de-Los-Santos, Maxy-B. ; Fernandez, Olga-L. ; Saravia, Nancy-G. ; Costa, Erika ; Melby, Peter-C. ; Travi, Bruno-L. | Public Library of Science | 2019-02-06T14:45:58ZCutaneous and mucosal leishmaniasis is widely distributed in Central and South America. Leishmania of the Viannia subgenus are the most frequent species infecting humans. L. (V.) braziliensis, L. (V.) panamensis are also responsible for metastat[...]![]()
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Sanchez Clemente, Nuria ; Ugarte-Gil, Cesar ; Solorzano, Nelson ; Maguina, Ciro ; Moore, David | Public Library of Science | 2019-02-22T14:55:02ZBackground Bartonellosis affects small Andean communities in Peru, Colombia and Ecuador. Research in this area has been limited. Methods Retrospective review of 191 cases of bartonellosis managed in Caraz District Hospital, Peru, during the last[...]![]()
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Schwarz, Alexandra ; Medrano-Mercado, Nora ; Schaub, Gunter A. ; Struchiner, Claudio J. ; Bargues, M. Dolores ; Levy, Michael Z. ; Ribeiro, Jose M. C. | Public Library of Science | 2020-06-10T18:12:17ZBACKGROUND: Triatoma infestans is the main vector of Chagas disease in South America. As in all hematophagous arthropods, its saliva contains a complex cocktail that assists blood feeding by preventing platelet aggregation and blood clotting an[...]![]()
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Oliveira, Larissa Rosa de ; Gehara, Marcelo C. M. ; Fraga, Lúcia D. ; Lopes, Fernando ; Túnez, Juan Ignacio ; Cassini, Marcelo H. ; Majluf, Patricia ; Cardenas-Alayza, Susana ; Pavés, Héctor J. ; Crespo, Enrique Alberto ; García, Nestor ; Loizaga de Castro, Rocío ; Hoelzel, A. Rus ; Sepúlveda, Maritza ; Olavarría, Carlos ; Valiati, Victor Hugo ; Quiñones, Renato ; Pérez-Alvarez, Maria Jose ; Ott, Paulo Henrique ; Bonatto, Sandro L. | Public Library of Science | 2019-01-25T15:02:17ZThe South American sea lion (Otaria flavescens) is widely distributed along the southern Atlantic and Pacific coasts of South America with a history of significant commercial exploitation. We aimed to evaluate the population genetic structure an[...]![]()
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Saavedra-Garcia, Lorena ; Bernabé-Ortiz, Antonio ; Gilman, Robert H. ; Diez-Canseco, Francisco ; Cardenas, Maria Kathia ; Sacksteder, Katherine A. ; Miranda, J. Jaime | Public Library of Science | 2019-02-06T14:53:10ZBACKGROUND: In resourced-constrained settings, daily cooking practices are still the norm. Replacing sodium in regular salt to produce potassium-enriched salts are potential alternative routes to reduce sodium intake, paired with the benefit as[...]![]()
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Flecker, Robert H. ; Pray, Ian W. ; Santivanez, Saul J. ; Ayvar, Viterbo ; Gamboa, Ricardo ; Muro, Claudio ; Moyano, Luz Maria ; Benavides, Victor ; Garcia, Hector H. ; O'Neal, Seth E. | Public Library of Science | 2019-01-25T15:02:18ZBACKGROUND: Taenia solium inflicts substantial neurologic disease and economic losses on rural communities in many developing nations. "Ring-strategy" is a control intervention that targets treatment of humans and pigs among clusters of househol[...]![]()
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Ruiz-Grosso, P. ; Cachay, R. ; de la Flor, A. ; Schwalb, A. ; Ugarte-Gil, C. | Public Library of Science | 2020-12-14T16:10:09ZBackground Depression is a common comorbidity of tuberculosis (TB) and is associated with poor adherence to treatment of multiple disorders. We conducted a systematic review to synthesize the existing evidence on the relationship between depress[...]![]()
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Barrios, Y.V. ; Gelaye, B. ; Zhong, Q. ; Nicolaidis, C. ; Rondon, M.B. ; Garcia, P.J. ; Mascaro Sanchez, P.A. ; Sánchez, S.E. ; Williams, M.A. | Public Library of Science | 2019-04-24T18:23:55ZObjective: We examined associations of childhood physical and sexual abuse with risk of intimate partner violence (IPV). We also evaluated the extent to which childhood abuse was associated with self-reported general health status and symptoms o[...]![]()
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Machicado, Claudia ; Machicado, Jorge-D. ; Maco, Vicente ; Terashima, Angélica ; Marcos, Luis-A. | Public Library of Science | 2019-02-06T14:45:37ZBACKGROUND: Fascioliasis has been sporadically associated with chronic liver disease on previous studies. In order to describe the current evidence, we carried out a systematic review to assess the association between fascioliasis with liver fib[...]![]()
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Folayan, Morenike-Oluwatoyin ; Harrison, Abigail ; Brown, Brandon ; Odetoyinbo, Morolake ; Stockman, Jamila-K. ; Ajuwon, Ademola-J. ; Caceres, Carlos-F. | Public Library of Science | 2019-02-06T14:45:13ZOBJECTIVES: Some individuals experience their first sexual intercourse through physically forced sex, which affects the way they experience and cope with stress. We examined differences in sexual risk behavior, experience of stressors, and use o[...]![]()
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De Lucia Rolfe, Emanuella ; de França, Giovanny Vinícius Araújo ; Vianna, Carolina Avila ; Gigante, Denise P. ; Miranda, J. Jaime ; Yudkin, John S. ; Horta, Bernardo Lessa ; Ong, Ken K. | Public Library of Science | 2018-11-30T02:09:30ZEarly life stunting may have long-term effects on body composition, resulting in obesity-related comorbidities. We tested the hypothesis that individuals stunted in early childhood may be at higher cardiometabolic risk later in adulthood. 1753 m[...]![]()
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López de la Lama, Rocío ; de la Puente, Santiago ; Riveros, Juan Carlos | Public Library of Science | 2018-11-30T02:09:30ZMisconceptions, lack of knowledge, and negative attitudes towards sharks act as barriers preventing actions required to tackle threats to shark populations, limiting the success of global shark conservation initiatives. Peru, a major player for [...]![]()
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de Ferrari, Aldo ; Gentille, Cesar ; Davalos, Long ; Huayanay, Leandro ; Malaga, German | Public Library of Science | 2020-06-10T18:12:19ZBACKGROUND: The interaction between physicians and the pharmaceutical industry influences physicians' attitudes and prescribing behavior. Although largely studied in the US, this topic has not been well studied in resource-poor settings, where a[...]![]()
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Correa, Malena ; Zimic, Mirko ; Barrientos, Franklin ; Barrientos, Ronald ; Roman-Gonzalez, Avid ; Pajuelo, Monica J. ; Anticona, Cynthia ; Mayta, Holger ; Alva, Alicia ; Solis-Vasquez, Leonardo ; Figueroa, Dante Anibal ; Chavez, Miguel A. ; Lavarello, Roberto ; Castañeda, Benjamin ; Paz-Soldan, Valerie A. ; Checkley, William ; Gilman, Robert H. ; Oberhelman, Richard | Public Library of Science | 2019-03-05T15:23:30ZPneumonia is one of the major causes of child mortality, yet with a timely diagnosis, it is usually curable with antibiotic therapy. In many developing regions, diagnosing pneumonia remains a challenge, due to shortages of medical resources. Lun[...]![]()
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Gracia Pacheco, Pablo de ; Gallego Collado, Beatriz Isabel ; Rojas López, María Blanca ; Ramírez Sebastián, Ana Isabel ; Hoz Montañana, María Rosa de ; Salazar Corral, Juan José ; Triviño Casado, Alberto ; Ramirez Sebastian, Jose Manuel | Public Library of Science | 2015-11-18Proliferation of microglial cells has been considered a sign of glial activation and a hallmark of ongoing neurodegenerative diseases. Microglia activation is analyzed in animal models of different eye diseases. Numerous retinal samples are requ[...]![]()
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Lopez-Garnier, Santiago ; Sheen, Patricia ; Zimic, Mirko | Public Library of Science | 2019-07-04T16:59:21ZTuberculosis is an infectious disease that causes ill health and death in millions of people each year worldwide. Timely diagnosis and treatment is key to full patient recovery. The Microscopic Observed Drug Susceptibility (MODS) is a test to d[...]![]()
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Tuberculosis is an infectious disease that causes ill health and death in millions of people each year worldwide. Timely diagnosis and treatment is key to full patient recovery. The Microscopic Observed Drug Susceptibility (MODS) is a test to di[...]![]()
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Castillo-Neyra, Ricardo ; Brown, Joanna ; Borrini, Katty ; Arevalo, Claudia ; Levy, Michael Z. ; Buttenheim, Alison ; Hunter, Gabrielle C. ; Becerra, Victor ; Behrman, Jere ; Paz-Soldan, Valerie A. | Public Library of Science | 2019-01-25T15:02:19ZBACKGROUND: Canine rabies was reintroduced to the city of Arequipa, Peru in March 2015. The Ministry of Health has conducted a series of mass dog vaccination campaigns to contain the outbreak, but canine rabies virus transmission continues in Ar[...]![]()
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Ammar, N. ; Aly, N.M. ; Folayan, M.O. ; Khader, Y. ; Virtanen, J.I. ; Al-Batayneh, O.B. ; Mohebbi, S.Z. ; Attia, S. ; Howaldt, H.-P. ; Boettger, S. ; Maharani, D.A. ; Rahardjo, A. ; Khan, I. ; Madi, M. ; Rashwan, M. ; Pavlic, V. ; Cicmil, S. ; Choi, Y.-H. ; Joury, E. ; Castillo, J.L. ; Noritake, K. ; Shamala, A. ; Galluccio, G. ; Polimeni, A. ; Phantumvanit, P. ; Mancino, D. ; Kim, J.-B. ; Abdelsalam, M.M. ; Arheiam, A. ; Dama, M.A. ; Nyan, M. ; Hussein, I. ; Alkeshan, M.M. ; Vukovic, A.P. ; Iandolo, A. ; Kemoli, A.M. ; El Tantawi, M. | Public Library of Science | 2020-12-14T16:06:01ZObjective COVID-19 pandemic led to major life changes. We assessed the psychological impact of COVID-19 on dental academics globally and on changes in their behaviors. Methods We invited dental academics to complete a cross-sectional, online sur[...]![]()
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Castillo-Neyraid, R. ; Buttenheim, A.M. ; Brown, J. ; Ferraraid, J.F. ; Arevalo-Nietoid, C. ; Borrini-Mayorí, K. ; Levy, M.Z. ; Becerra, V. ; Paz-Soldan, V.A. | Public Library of Science | 2020-12-14T16:06:15ZA canine rabies epidemic started in early 2015 in Arequipa, Peru and the rabies virus continues to circulate in the dog population. Some city residents who suffer dog bites do not seek care or do not complete indicated post-exposure prophylaxis [...]![]()
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Ibanez-Erquiaga, Bruno ; Pacheco, Aldo S. ; Rivadeneira, Marcelo M. ; Tejada, Claudia L. | Public Library of Science | 2019-03-05T15:23:30ZThe biogeography of the Peruvian Eastern Pacific coast has been described based on oceanographic parameters and qualitative species occurrence data. This has generated disagreement about the limits and existence of different biogeographic units.[...]![]()
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López Cantalapiedra, Juan ; Hernández Fernández, Manuel ; Morales, Jorge | Public Library of Science | 2011The resource-use hypothesis proposed by E.S. Vrba predicts that specialist species have higher speciation and extinction rates than generalists because they are more susceptible to environmental changes and vicariance. In this work, we test some[...]![]()
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Tapia, Vilma ; Betran, Ana-Pilar ; Gonzales, Gustavo-F. | Public Library of Science | 2019-02-06T14:48:07ZINTRODUCTION: Cesarean section rates continue to increase worldwide while the reasons appear to be multiple, complex and, in many cases, country specific. Over the last decades, several classification systems for caesarean section have been cre[...]![]()
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Zafra-Tanaka, J.H. ; Tenorio-Mucha, J. ; Villarreal-Zegarra, D. ; Carrillo-Larco, R. ; Bernabé-Ortiz, A. | Public Library of Science | 2020-12-14T16:11:09ZObjectives: In the last decade, Latin American (LA) countries, like Peru, have undergone an epidemiological transition that has changed the pattern of oncological cases. Given that Peru's oncological pattern could illustrate those of other LA co[...]![]()
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Petrova, Dafina ; Mas, Guiliana ; Navarrete, Gorka ; Rodriguez, Tania Tello ; Ortiz, Pedro J. ; Garcia-Retamero, Rocio | Public Library of Science | 2019-08-08T15:23:47ZWe investigated what factors may foster or hinder physicians' cancer screening risk literacy-specifically the ability to understand evidence regarding screening effectiveness and make evidence-based recommendations to patients. In an experiment,[...]![]()
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Petrova, Dafina ; Mas, Guiliana ; Navarrete, Gorka ; Rodriguez, Tania Tello ; Ortiz, Pedro J. ; Garcia-Retamero, Rocio | Public Library of Science | 2019-12-06T21:02:53ZWe investigated what factors may foster or hinder physicians' cancer screening risk literacy-specifically the ability to understand evidence regarding screening effectiveness and make evidence-based recommendations to patients. In an experiment,[...]![]()
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Keogh, Sarah C. ; Stillman, Melissa ; Awusabo-Asare, Kofi ; Sidze, Estelle ; Monzón, Ana Silvia ; Motta, Angelica ; Leong, Ellie | Public Library of Science | 2018-11-30T02:09:31ZSchool-based comprehensive sexuality education (CSE) can help adolescents achieve their full potential and realize their sexual and reproductive health and rights. This is particularly pressing in low- and middle-income countries (LMICs), where [...]![]()
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Blanco Imperiali, Ayelén M. ; Gómez Boronat, Miguel ; Alonso Gómez, Ángel Luis ; Yufa, Roman ; Unniappan, Suraj ; Delgado Saavedra, María Jesús ; Valenciano González, Ana Isabel | Public Library of Science | 2017-02-08Ghrelin is the only known hormone posttranslationally modified with an acylation. This modification is crucial for most of ghrelin’s physiological effects and is catalyzed by the polytopic enzyme ghrelin O-acyltransferase (GOAT). The aim of this[...]![]()
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Dornakova, Veronika ; Salazar-Sanchez, Renzo ; Borrini-Mayori, Katty ; Carrion-Navarro, Oscar ; Levy, Michael Z. ; Schaub, Gunter A. ; Schwarz, Alexandra | Public Library of Science | 2020-06-10T18:12:16ZBACKGROUND: Salivary proteins of Triatoma infestans elicit humoral immune responses in their vertebrate hosts. These immune responses indicate exposure to triatomines and thus can be a useful epidemiological tool to estimate triatomine infesta[...]![]()
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Silva, Claudia ; Betancor, Laura ; García, Coralith ; Astocondor, Lizeth ; Hinostroza, Noemi ; Bisio, Julieta ; Rivera, Javier ; Perezgasga, Lucía ; Pérez Escanda, Victoria ; Yim, Lucía ; Jacobs, Jan ; García-Del Portillo, Francisco ; SalmoIber CYTED Network ; Chabalgoity, José A. ; Puente, José L. | Public Library of Science | 2019-01-25T15:02:20ZIn this study, different molecular typing tools were applied to characterize 95 Salmonella enterica blood isolates collected between 2008 and 2013 from patients at nine public hospitals in Lima, Peru. Combined results of multiplex PCR serotyping[...]![]()
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Carrillo-Larco, Rodrigo M. ; Bernabé-Ortiz, Antonio ; Miranda, J. Jaime ; Xue, Hong ; Wang, Youfa | Public Library of Science | 2019-01-25T15:02:20ZThe aim of the study was to estimate the association between maternal perception of their child's health status and (mis)classification of their child's actual weight with future weight change. We present cross-sectional and longitudinal analyse[...]![]()
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Heinrich, Erica C. ; Djokic, Matea A. ; Gilbertson, Dillon ; DeYoung, Pamela N. ; Bosompra, Naa-Oye ; Wu, Lu ; Anza-Ramirez, Cecilia ; Orr, Jeremy E. ; Powell, Frank L. ; Malhotra, Atul ; Simonson, Tatum S. | Public Library of Science | 2019-12-06T20:57:47ZImpairments in cognitive function, mood, and sleep quality occur following ascent to high altitude. Low oxygen (hypoxia) and poor sleep quality are both linked to impaired cognitive performance, but their independent contributions at high altit[...]![]()
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Heinrich, Erica C. ; Djokic, Matea A. ; Gilbertson, Dillon ; DeYoung, Pamela N. ; Bosompra, Naa-Oye ; Wu, Lu ; Anza-Ramirez, Cecilia ; Orr, Jeremy E. ; Powell, Frank L. ; Malhotra, Atul ; Simonson, Tatum S. | Public Library of Science | 2019-07-04T16:59:25ZImpairments in cognitive function, mood, and sleep quality occur following ascent to high altitude. Low oxygen (hypoxia) and poor sleep quality are both linked to impaired cognitive performance, but their independent contributions at high altit[...]![]()
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Alnasser, Yossef ; Ferradas, Cusi ; Clark, Taryn ; Calderón, Maritza ; Gurbillon, Alejandro ; Gamboa, Dionicia ; McKakpo, Uri S. ; Quakyi, Isabella A. ; Bosompem, Kwabena M. ; Sullivan, David J. ; Vinetz, Joseph M. ; Gilman, Robert H. | Public Library of Science | 2019-02-06T14:45:09ZPlasmodium vivax is the most prevalent cause of human malaria in the world and can lead to severe disease with high potential for relapse. Its genetic and geographic diversities make it challenging to control. P. vivax is understudied and to ach[...]![]()
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Ruiz-Grosso, Paulo ; Ramos, Mariana ; Samalvides, Frine ; Vega-Dienstmaier, Johann ; Kruger, Hever | Public Library of Science | 2020-06-10T18:12:19ZBACKGROUND: Traffic related injuries are leading contributors to burden of disease worldwide. In developing countries a high proportion of them can be attributed to public transportation vehicles. Several mental disorders including alcohol and [...]![]()
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Tuero, Iskra ; Palma, Sandra ; Cabeza, Franco ; Saleemi, Sarah ; Rodriguez, Silvia ; Gonzales, Isidro ; Mayta, Holger ; Mahanty, Siddhartha ; Garcia, Hector H. ; Gilman, Robert H. | Public Library of Science | 2019-02-06T14:53:09ZBACKGROUND: The ability of Taenia solium to modulate the immune system likely contributes to their longevity in the human host. We tested the hypothesis that the nature of the immune response is related to the location of parasite and clinical m[...]![]()
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Rudgard, William E. ; Evans, Carlton A. ; Sweeney, Sedona ; Wingfield, Tom ; Lonnroth, Knut ; Barreira, Draurio ; Boccia, Delia | Public Library of Science | 2019-01-25T15:02:21ZBACKGROUND: Illness-related costs for patients with tuberculosis (TB) ?20% of pre-illness annual household income predict adverse treatment outcomes and have been termed "catastrophic." Social protection initiatives, including cash transfers, ar[...]![]()
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Sacristán Reviriego, Almudena ; Madrid, Marisa ; Cansado, José ; Martín, Humberto ; Molina, María | Public Library of Science | 2014-01-22Dual-specificity MAPK phosphatases (MKPs) are essential for the negative regulation of MAPK pathways. Similar to other MAPK-interacting proteins, most MKPs bind MAPKs through specific docking domains known as D-motifs. However, we found that the[...]![]()
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Oberhelman, Richard A. ; Soto-Castellares, Giselle ; Gilman, Robert H. ; Castillo, Maria E. ; Kolevic, Lenka ; Delpino, Trinidad ; Saito, Mayuko ; Salazar-Lindo, Eduardo ; Negron, Eduardo ; Montenegro, Sonia ; Laguna-Torres, V. Alberto ; Maurtua-Neumann, Paola ; Datta, Sumona ; Evans, Carlton A. | Public Library of Science | 2019-02-06T14:53:11ZBACKGROUND: Diagnosing tuberculosis in children is challenging because specimens are difficult to obtain and contain low tuberculosis concentrations, especially with HIV-coinfection. Few studies included well-controls so test specificities are [...]![]()
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Grandjean, Louis ; Gilman, Robert H. ; Iwamoto, Tomatada ; Koser, Claudio U. ; Coronel, Jorge ; Zimic, Mirko ; Torok, M. Estee ; Ayabina, Diepreye ; Kendall, Michelle ; Fraser, Christophe ; Harris, Simon ; Parkhill, Julian ; Peacock, Sharon J. ; Moore, David A. J. ; Colijn, Caroline | Public Library of Science | 2019-01-25T15:02:21ZBACKGROUND: Multidrug-resistant tuberculosis poses a major threat to the success of tuberculosis control programs worldwide. Understanding how drug-resistant tuberculosis evolves can inform the development of new therapeutic and preventive strat[...]![]()
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Lee, Gwenyth O. ; Comina, Germán ; Hernández-Córdova, Gustavo ; Naik, Nehal ; Gayoso, Oscar ; Ticona, Eduardo ; Coronel, Jorge ; Evans, Carlton A. ; Zimic, Mirko ; Paz-Soldan, Valerie A. ; Gilman, Robert H. ; Oberhelman, Richard | Public Library of Science | 2020-07-14T00:02:31ZCough is a characteristic symptom of tuberculosis, is the main cause of transmission, and is used to assess treatment response. We aimed to identify the best measure of cough severity and characterize changes during initial tuberculosis therapy.[...]![]()
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Mastel, Molly ; Bussalleu, Alejandra ; Paz-Soldan, Valerie A. ; Salmón-Mulanovich, Gabriela ; Valdés-Velásquez, Armando ; Hartinger, Stella M. | Public Library of Science | 2018-11-30T03:10:43ZLand use change (LUC) is a main cause of global environmental change, and is an important activity to be studied. Our research aims to examine the current state of evidence on the link between LUC and human health in the Amazon region. We conduc[...]![]()
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Martín-Francés, Laura ; Martinón Torres, María ; Martínez de Pinillos, Marina ; García Campos, Cecilia ; Zanolli, Clément ; Bayle, Priscilla ; Modesto Mata, Mario ; Arsuaga, Juan Luis ; Bermúdez de Castro, José María | Public Library of Science | 2020-06-08Dental enamel thickness, topography, growth and development vary among hominins. In Homo, the thickness of dental enamel in most Pleistocene hominins display variations from thick to hyper-thick, while Neanderthals exhibit proportionally thinner[...]![]()
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Wolff, Marcelo J. ; Giganti, Mark J. ; Cortes, Claudia P. ; Cahn, Pedro ; Grinsztejn, Beatriz ; Pape, Jean W. ; Padgett, Denis ; Sierra-Madero, Juan ; Gotuzzo, Eduardo ; Duda, Stephany N. ; McGowan, Catherine C. ; Shepherd, Bryan E. ; CCASAnet | Public Library of Science | 2019-01-25T15:02:13ZBACKGROUND: In Latin America, the first wave of HIV-infected patients initiated highly active antiretroviral therapy (HAART) 10 or more years ago. Characterizing their treatment experience and corresponding outcomes across a decade of HAART may [...]![]()
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Wingfield, Tom ; Boccia, Delia ; Tovar, Marco ; Gavino, Arquimedes ; Zevallos, Karine ; Montoya, Rosario ; Lonnroth, Knut ; Evans, Carlton A. | Public Library of Science | 2020-06-10T18:12:16ZBACKGROUND: Even when tuberculosis (TB) treatment is free, hidden costs incurred by patients and their households (TB-affected households) may worsen poverty and health. Extreme TB-associated costs have been termed "catastrophic" but are poorl[...]![]()
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Ding, Xavier C. ; Ade, Maria Paz ; Baird, J. Kevin ; Cheng, Qin ; Cunningham, Jane ; Dhorda, Mehul ; Drakeley, Chris ; Felger, Ingrid ; Gamboa, Dionicia ; Harbers, Matthias ; Herrera, Socrates ; Lucchi, Naomi ; Mayor, Alfredo ; Mueller, Ivo ; Sattabongkot, Jetsumon ; Ratsimbason, Arsene ; Richards, Jack ; Tanner, Marcel ; Gonzalez, Iveth J. | Public Library of Science | 2019-01-25T15:02:22ZThe global prevalence of malaria has decreased over the past fifteen years, but similar gains have not been realized against Plasmodium vivax because this species is less responsive to conventional malaria control interventions aimed principally[...]![]()
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Single, R.M. ; Meyer, D. ; Nunes, K. ; Francisco, R.S. ; Hünemeier, T. ; Maiers, M. ; Hurley, C.K. ; Bedoya, G. ; Gallo, C. ; Hurtado, A.M. ; Llop, E. ; Petzl-Erler, M.L. ; Poletti, G. ; Rothhammer, F. ; Tsuneto, L. ; Klitz, W. ; Ruiz-Linares, A. | Public Library of Science | 2020-12-14T16:10:14ZThe American continent was the last to be occupied by modern humans, and native populations bear the marks of recent expansions, bottlenecks, natural selection, and population substructure. Here we investigate how this demographic history has sh[...]![]()
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Paz-Soldan, Valerie-A. ; Yukich, Josh ; Soonthorndhada, Amara ; Giron, Maziel ; Apperson, Charles-S. ; Ponnusamy, Loganathan ; Schal, Coby ; Morrison, Amy-C. ; Keating, Joseph ; Wesson, Dawn-M. | Public Library of Science | 2019-02-06T14:45:57ZBACKGROUND: Dengue virus (and Chikungunya and Zika viruses) is transmitted by Aedes aegypti and Aedes albopictus mosquitoes and causes considerable human morbidity and mortality. As there is currently no vaccine or chemoprophylaxis to protect p[...]![]()
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Rowneki, M. ; Aronson, N. ; Du, P. ; Sachs, P. ; Blakemore, R. ; Chakravorty, S. ; Levy, S. ; Jones, A.L. ; Trivedi, G. ; Chebore, S. ; Addo, D. ; Byarugaba, D.K. ; Njobvu, P.D. ; Wabwire-Mangen, F. ; Erima, B. ; Ramos, E.S. ; Evans, C.A. ; Hale, B. ; Mancuso, J.D. ; Alland, D. | Public Library of Science | 2020-12-14T16:10:08ZBackground Drug susceptibility testing for Mycobacterium tuberculosis (MTB) is difficult to perform in resource-limited settings where Acid Fast Bacilli (AFB) smears are commonly used for disease diagnosis and monitoring. We developed a simple m[...]![]()
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Vargas-Cuentas, Natalia I. ; Roman-Gonzalez, Avid ; Gilman, Robert H. ; Barrientos, Franklin ; Ting, James ; Hidalgo, Daniela ; Jensen, Kelly ; Zimic, Mirko | Public Library of Science | 2019-01-25T15:18:33ZBACKGROUND: Autism spectrum disorder (ASD) currently affects nearly 1 in 160 children worldwide. In over two-thirds of evaluations, no validated diagnostics are used and gold standard diagnostic tools are used in less than 5% of evaluations. Cur[...]![]()
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Felgner, Jiin ; Jain, Aarti ; Nakajima, Rie ; Liang, Li ; Jasinskas, Algis ; Gotuzzo, Eduardo ; Vinetz, Joseph M. ; Miyajima, Fabio ; Pirmohamed, Munir ; Hassan-Hanga, Fatimah ; Umoru, Dominic ; Jibir, Binta Wudil ; Gambo, Safiya ; Olateju, Kudirat ; Felgner, Philip L. ; Obaro, Stephen ; Davies, D. Huw | Public Library of Science | 2019-01-25T15:18:33ZImproved serodiagnostic tests for typhoid fever (TF) are needed for surveillance, to facilitate patient management, curb antibiotic resistance, and inform public health programs. To address this need, IgA, IgM and IgG ELISAs using Salmonella ent[...]![]()
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De Los Angeles Lazo, M. ; Bernabé-Ortiz, A. ; Pinto, M.E. ; Ticse, R. ; Malaga, G. ; Sacksteder, K. ; Miranda, J.J. ; Gilman, R.H. | Public Library of Science | 2020-06-10T18:12:17ZAim: We aimed to estimate the morbidity rate and associated factors for diabetic peripheral neuropathy (DPN) in a low-middle income country setting. Methods: Cross-sectional study, data was gathered at Peru's Ministry of Health national speciali[...]![]()
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Lazo, Maria de los Angeles ; Bernabé-Ortiz, Antonio ; Pinto, Miguel E. ; Ticse, Ray ; Malaga, German ; Sacksteder, Katherine ; Miranda, J. Jaime ; Gilman, Robert H. | Public Library of Science | 2020-06-10T18:12:17ZAIM: We aimed to estimate the morbidity rate and associated factors for diabetic peripheral neuropathy (DPN) in a low-middle income country setting. METHODS: Cross-sectional study, data was gathered at Peru's Ministry of Health national special[...]![]()
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Zhong, Q.Y. ; Gelaye, B. ; Zaslavsky, A.M. ; Fann, J.R. ; Rondon, M.B. ; Sánchez, S.E. ; Williams, M.A. | Public Library of Science | 2019-04-24T18:23:57ZObjective: Generalized anxiety disorder (GAD) during pregnancy is associated with several adverse maternal and perinatal outcomes. A reliable and valid screening tool for GAD should lead to earlier detection and treatment. Among pregnant Peruvia[...]![]()
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Berry, Alexander S. F. ; Salazar-Sanchez, Renzo ; Castillo-Neyra, Ricardo ; Borrini-Mayori, Katty ; Arevalo-Nieto, Claudia ; Chipana-Ramos, Claudia ; Vargas-Maquera, Melina ; Ancca-Juarez, Jenny ; Naquira-Velarde, Cesar ; Levy, Michael Z. ; Brisson, Dustin | Public Library of Science | 2020-07-14T00:00:57ZAnthropogenic environmental alterations such as urbanization can threaten native populations as well as create novel environments that allow human pests and pathogens to thrive. As the number and size of urban environments increase globally, it [...]![]()
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Zorrilla, Victor ; De Los Santos, Maxy B. ; Espada, Liz ; Santos, Rocío Del Pilar ; Fernández, Roberto ; Urquia, Albino ; Stoops, Craig A. ; Ballard, Sarah-Blythe ; Lescano, Andres G. ; Vásquez, Gissella M. ; Valdivia, Hugo O. | Public Library of Science | 2019-01-25T15:18:33ZBACKGROUND: Cutaneous leishmaniasis (CL) is an important health problem in the New World affecting civilian and military populations that are frequently exposed in endemic settings. The Peruvian region of Madre de Dios located near the border wi[...]![]()
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Buffarini, Romina ; Restrepo-Mendez, Maria-Clara ; Silveira, Vera-M. ; Miranda, Jaime-J. ; Goncalves, Helen-D. ; Oliveira, Isabel-O. ; Horta, Bernardo-L. ; Gigante, Denise-P. ; Menezes, Ana-Maria ; Assuncao, Maria-Cecilia-F. | Public Library of Science | 2019-02-06T14:45:11ZAIM: Glycated haemoglobin (HbA1c), a marker of glucose control in individuals with diabetes mellitus, is also related with the incidence of cardiometabolic risk in populations free of disease. The aim of this study was to describe the distributi[...]![]()
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Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites.
Knuepfer, Ellen ; Wright, Katherine E. ; Kumar Prajapati, Surendra ; Rawlinson, Thomas A. ; Mohring, Franziska ; Koch, Marion ; Lyth, Oliver R. ; Howell, Steven A. ; Villasis, Elizabeth ; Snijders, Ambrosius P. ; Moon, Robert W. ; Draper, Simon J. ; Rosanas-Urgell, Anna ; Higgins, Matthew K. ; Baum, Jake ; Holder, Anthony A. | Public Library of Science | 2019-12-06T21:02:54ZMalaria is caused by Plasmodium parasites, which invade and replicate in erythrocytes. For Plasmodium falciparum, the major cause of severe malaria in humans, a heterotrimeric complex comprised of the secreted parasite proteins, PfCyRPA, PfRIPR [...]![]()
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Knuepfer, Ellen ; Wright, Katherine E. ; Kumar Prajapati, Surendra ; Rawlinson, Thomas A. ; Mohring, Franziska ; Koch, Marion ; Lyth, Oliver R. ; Howell, Steven A. ; Villasis, Elizabeth ; Snijders, Ambrosius P. ; Moon, Robert W. ; Draper, Simon J. ; Rosanas-Urgell, Anna ; Higgins, Matthew K. ; Baum, Jake ; Holder, Anthony A. | Public Library of Science | 2019-07-04T16:59:29ZMalaria is caused by Plasmodium parasites, which invade and replicate in erythrocytes. For Plasmodium falciparum, the major cause of severe malaria in humans, a heterotrimeric complex comprised of the secreted parasite proteins, PfCyRPA, PfRIPR [...]![]()
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Shah, Jyotsna ; Weltman, Helena ; Narciso, Patricia ; Murphy, Christina ; Poruri, Akhila ; Baliga, Shrikala ; Sharon, Leesha ; York, Mary ; Cunningham, Gail ; Miller, Steve ; Caviedes, Luz ; Gilman, Robert ; Desmond, Edward ; Ramasamy, Ranjan | Public Library of Science | 2019-01-25T15:18:33ZTwo rapid dual color fluorescence in situ hybridization (FISH) assays were evaluated for detecting M. tuberculosis and related pathogens in cultures. The MN Genus-MTBC FISH assay uses an orange fluorescent probe specific for the Mycobacterium tu[...]![]()
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Planas, Maria-Elena ; García, Patricia J. ; Bustelo, Monserrat ; Carcamo, Cesar P. ; Martinez, Sebastian ; Nopo, Hugo ; Rodríguez, Julio ; Merino, Maria-Fernanda ; Morrison, Andrew | Public Library of Science | 2019-02-06T14:53:12ZMost studies reporting ethnic disparities in the quality of healthcare come from developed countries and rely on observational methods. We conducted the first experimental study to evaluate whether health providers in Peru provide differential [...]![]()
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Huicho, Luis ; Huayanay-Espinoza, Carlos A. ; Hernandez, Patricia ; Niño de Guzman, Jessica ; Rivera-Ch, Maria | Public Library of Science | 2018-11-30T03:10:45ZWe compared expenditure trends for reproductive, maternal, neonatal and child health (RMNCH) with trends in RMNCH service coverage in Peru. We used National Health Accounts data to report on total health expenditure by source; the Countdown data[...]![]()
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Franco-Paredes, Carlos ; Khan, M. Imran ; Gonzalez-Diaz, Esteban ; Santos-Preciado, Jose-I. ; Rodriguez-Morales, Alfonso-J. ; Gotuzzo, Eduardo | Public Library of Science | 2019-02-06T14:51:19Z![]()
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Ballard, Sarah-Blythe ; Reaves, Erik J. ; Luna, C. Giannina ; Silva, Maria E. ; Rocha, Claudio ; Heitzinger, Kristen ; Saito, Mayuko ; Apaza, Sonia ; Espetia, Susan ; Blazes, David L. ; Tilley, Drake H. ; Guzman Aguilar, Rene C. ; Gilman, Robert H. ; Bausch, Daniel G. | Public Library of Science | 2019-02-06T14:53:10ZBACKGROUND: Successful vaccination strategies against norovirus will require understanding the burden of disease and relevant genotypes in populations. However, few data are available from cohort studies of adults living in low- and middle-inco[...]![]()
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Barbosa, Susana ; Gozze, Amanda B. ; Lima, Nathalia F. ; Batista, Camilla L. ; Bastos, Melissa da Silva ; Nicolete, Vanessa C. ; Fontoura, Pablo S. ; Goncalves, Raquel M. ; Viana, Susana Ariane S. ; Menezes, Maria Jose ; Scopel, Kezia Katiani G. ; Cavasini, Carlos E. ; Malafronte, Rosely dos Santos ; da Silva-Nunes, Monica ; Vinetz, Joseph M. ; Castro, Marcia C. ; Ferreira, Marcelo U. | Public Library of Science | 2020-06-10T18:12:16ZBACKGROUND: New frontier settlements across the Amazon Basin pose a major challenge for malaria elimination in Brazil. Here we describe the epidemiology of malaria during the early phases of occupation of farming settlements in Remansinho area, [...]![]()
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Miranda, J. Jaime ; Lopez-Rivera, Luis A. ; Quistberg, D. Alex ; Rosales-Mayor, Edmundo ; Gianella, Camila ; Paca-Palao, Ada ; Luna, Diego ; Huicho, Luis ; Paca, Ada | Public Library of Science | 2020-06-10T18:12:18ZBACKGROUND: The epidemiological profile and trends of road traffic injuries (RTIs) in Peru have not been well-defined, though this is a necessary step to address this significant public health problem in Peru. The objective of this study was to [...]![]()
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Metcalf, Tatiana ; Soria, Jaime ; Montano, Silvia M. ; Ticona, Eduardo ; Evans, Carlton A. ; Huaroto, Luz ; Kasper, Matthew ; Ramos, Eric S. ; Mori, Nicanor ; Jittamala, Podjanee ; Chotivanich, Kesinee ; Chavez, Irwin F. ; Singhasivanon, Pratap ; Pukrittayakamee, Sasithon ; Zunt, Joseph R. | Public Library of Science | 2018-11-30T03:10:46ZBACKGROUND: Meningitis caused by Mycobacterium tuberculosis is a major cause of morbidity and mortality worldwide. We evaluated the performance of cerebrospinal fluid (CSF) testing with the GeneXpert MTB/RIF assay versus traditional approaches f[...]![]()
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Mekonnen, B. ; Mihret, A. ; Getahun, M. ; Hailu, T. ; Sidiki, S. ; Kelley, H.V. ; Scordo, J.M. ; Hunt, W.G. ; Pan, X. ; Balada-Llasat, J.-M. ; Gebreyes, W. ; Evans, C.A. ; Aseffa, A. ; Torrelles, J.B. ; Wang, S.-H. ; Abebe, T. | Public Library of Science | 2019-07-04T16:59:34ZTimely diagnosis of tuberculosis (TB) is limited in Ethiopia. We evaluated the performance of a low technology, thin layer agar, Mycobacterium tuberculosis (M.tb) culture color plate (TB-CX) test with concurrent drug susceptibility testing (DST)[...]![]()
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Marzal, Miguel ; Guerra-Giraldez, Cristina ; Paredes, Adriana ; Cangalaya, Carla ; Rivera, Andrea ; Gonzalez, Armando E. ; Mahanty, Siddhartha ; Garcia, Hector H. ; Nash, Theodore E. | Public Library of Science | 2020-06-10T18:12:17ZCysticidal drug treatment of viable Taenia solium brain parenchymal cysts leads to an acute pericystic host inflammatory response and blood brain barrier breakdown (BBB), commonly resulting in seizures. Naturally infected pigs, untreated or trea[...]![]()
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Bernabé-Ortiz, Antonio ; Ruiz-Alejos, Andrea ; Miranda, J. Jaime ; Mathur, Rohini ; Perel, Pablo ; Smeeth, Liam | Public Library of Science | 2019-01-25T15:18:34ZOBJECTIVES: The EZSCAN is a non-invasive device that, by evaluating sweat gland function, may detect subjects with type 2 diabetes mellitus (T2DM). The aim of the study was to conduct a systematic review and meta-analysis including studies asses[...]![]()
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Concha-Velasco, Fatima ; González-Lagos, Elsa ; Seas, Carlos ; Bustamante, Beatriz | Public Library of Science | 2019-01-25T15:18:35ZINTRODUCTION: The first-line combination therapy for HIV-associated cryptococcal meningitis (CM), a condition of high mortality particularly in the first two weeks of treatment, consists of amphotericin B plus flucytosine (5-FC). Given that 5-FC[...]![]()
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Lee, Chan ; Noh, John ; O'Neal, Seth E. ; Gonzalez, Armando E. ; Garcia, Hector H. ; Handali, Sukwan | Public Library of Science | 2019-12-06T21:02:59ZWe developed a novel and portable fluorescent sensor that integrates a lateral flow assay with a quantum dot (Qdots) label and a mobile phone reader for detection of specific antibodies in human serum. We evaluated the utility of this assay to t[...]![]()
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Nabeta, Pamela ; Havumaki, Joshua ; Ha, Dang Thi Minh ; Cáceres, Tatiana ; Hang, Pham Thu ; Collantes, Jimena ; Thi Ngoc Lan, Nguyen ; Gotuzzo, Eduardo ; Denkinger, Claudia M. | Public Library of Science | 2019-01-25T15:18:35ZBACKGROUND: Improved and affordable diagnostic or triage tests are urgently needed at the microscopy centre level. Automated digital microscopy has the potential to overcome issues related to conventional microscopy, including training time requ[...]![]()
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Martin, Laura ; Coronel, Jorge ; Faulx, Dunia ; Valdez, Melissa ; Metzler, Mutsumi ; Crudder, Chris ; Castillo, Edith ; Caviedes, Luz ; Grandjean, Louis ; Rodriguez, Mitzi ; Friedland, Jon S. ; Gilman, Robert H. ; Moore, David A. J. | Public Library of Science | 2020-06-10T18:12:20ZBACKGROUND: Even though the WHO-endorsed, non-commercial MODS assay offers rapid, reliable TB liquid culture and phenotypic drug susceptibility testing (DST) at lower cost than any other diagnostic, uptake has been patchy. In part this reflects [...]![]()
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Wynn, Adriane ; Cabeza, Jeanne ; Adachi, Kristina ; Needleman, Jack ; García, Patricia J. ; Klausner, Jeffrey D. | Public Library of Science | 2019-02-06T14:53:12ZOBJECTIVE: This study describes the pregnancy and birth outcomes at two hospitals in Lima, Peru. The data collection and analysis is intended to inform patients, providers, and policy makers on Peru's progress toward achieving the Millennium Dev[...]![]()
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Belaunzaran-Zamudio, Pablo F. ; Caro-Vega, Yanink ; Giganti, Mark J. ; Castilho, Jessica L. ; Crabtree-Ramirez, Brenda E. ; Shepherd, Bryan E. ; Mejia, Fernando ; Cesar, Carina ; Moreira, Rodrigo C. ; Wolff, Marcelo ; Pape, Jean W. ; Padgett, Denis ; McGowan, Catherine C. ; Sierra-Madero, Juan G. | Public Library of Science | 2020-07-14T00:00:56ZBACKGROUND: A growing population of older adults with HIV will increase demands on HIV-related healthcare. Nearly a quarter of people receiving care for HIV in Latin America are currently 50 years or older, yet little is known about the frequenc[...]![]()
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Wolniczak, Isabella ; Cáceres-DelAguila, José A. ; Maguiña, Jorge L. ; Bernabé-Ortiz, Antonio | Public Library of Science | 2019-01-25T15:18:35ZOBJECTIVES: Among different factors, diet patterns seem to be related to depression. The aim of this study was to evaluate the association between the consumption of fruits and/or vegetables and depressive symptoms. METHODOLOGY/PRINCIPAL FINDING[...]![]()
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Wolniczak, Isabella ; Cáceres-DelAguila, José A. ; Maguiña, Jorge L. ; Bernabé-Ortiz, Antonio | Public Library of Science | 2017-10-21T15:30:53ZObjectives: Among different factors, diet patterns seem to be related to depression. The aim of this study was to evaluate the association between the consumption of fruits and/or vegetables and depressive symptoms. Methodology/Principal finding[...]![]()
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Ng-Sueng, L.F. ; Vargas-Matos, I. ; Mayta-Tristán, P. ; Pereyra-Elías, R. ; Montenegro-Idrogo, J.J. ; Inga-Berrospi, F. ; Ancalli, F. ; Bonilla-Escobar, F. ; Diaz-Velez, C. ; Gutierrez-Quezada, E. ; Gomez-Alhach, J. ; Muñoz-Medina, C.E. ; Sanchez-Pozo, A. ; Vidal, M. ; Pozo, A.M.S. ; Cardozo López, Juan Pablo ; Panozo, S.L. ; Villar, R. ; Morales, R.S. ; Adauy, G.A. ; Toloza, P.A. ; De Aguilera Aedo, R.O. ; González, J.P.S. ; Brito, I.N. ; Avendaño, J.S. ; Romero, F. ; Alhach, J.G. ; Escobar, F.B. ; Calixto, O. ; Cardona, Á.M. ; Arias, J.L.O. ; Cifuentes, L.A. ; Acosta, K. ; Ospina, M. ; Ruíz, G.D.L. ; Cifuentes, A.F.Q. ; Ortega, I.B. ; Valverde, C. ; Fernández, J.B. ; Urrutia, L.E.C. ; Moya, G. ; Yescas, G. ; León, M.V. ; Gutiérrez, E. ; Peralta, R.M.I.A. ; Sulca, R.V. ; Urbina, J.A.G. ; León, F. ; Díaz, C. ; Cabrera, J. ; Berrospi, F.I. ; Muñoz, K.M. ; Loaiza, O.M. ; Torres, M.M. ; Figueroa, J.Á. ; Dextre, M.T. ; Purizaca-Rosillo, N. ; Vidal, O.R. ; Chambi, D.E.V. ; Alfonso, M. ; Castagnino, D.L. ; Mogollón, C. ; Maquera, J. ; Johnson Franco, Mario ; Gómez, G.F. ; Castro, J.J. ; Vela, E.J.J. ; Sampé, M.O. ; García, G.R.V. ; Anaya, K.R.H. ; Calizaya, F.A. ; Lázaro, L.E.G. ; Medina, C.E.M. ; Rodríguez, M.A. ; Da Silva-Abreu, A. | Public Library of Science | 2019-02-22T14:55:00ZIntroduction: The selection of a medical specialty has been associated with multiple factors, such as personal preferences, academic exposure, motivational factors and sociodemographic factors, such as gender. The number of women in the medical [...]![]()
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Gender-dependent differences in plasma matrix metalloproteinase-8 elevated in pulmonary tuberculosis
Sathyamoorthy, T. ; Sandhu, G. ; Tezera, L.B. ; Thomas, R. ; Singhania, A. ; Woelk, C.H. ; Dimitrov, B.D. ; Agranoff, D. ; Evans, C.A.W. ; Friedland, J.S. ; Elkington, P.T. | Public Library of Science | 2019-04-24T18:23:57ZTuberculosis (TB) remains a global health pandemic and greater understanding of underlying pathogenesis is required to develop novel therapeutic and diagnostic approaches. Matrix metalloproteinases (MMPs) are emerging as key effectors of tissue [...]![]()
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Pajuelo, Monica J. ; Eguiluz, María ; Roncal, Elisa ; Quiñones-García, Stefany ; Clipman, Steven J. ; Calcina, Juan ; Gavidia, Cesar M. ; Sheen, Patricia ; Garcia, Hector H. ; Gilman, Robert H. ; Gonzalez, Armando E. ; Zimic, Mirko ; Cysticercosis Working Group in Peru | Public Library of Science | 2019-01-25T15:18:36ZThe adult Taenia solium, the pork tapeworm, usually lives as a single worm in the small intestine of humans, its only known definitive host. Mechanisms of genetic variation in T. solium are poorly understood. Using three microsatellite markers p[...]![]()
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Wu, Sijie ; Zhang, Manfei ; Yang, Xinzhou ; Peng, Fuduan ; Zhang, Juan ; Tan, Jingze ; Yang, Yajun ; Wang, Lina ; Hu, Yanan ; Peng, Qianqian ; Li, Jinxi ; Liu, Yu ; Guan, Yaqun ; Chen, Chen ; Hamer, Merel A. ; Nijsten, Tamar ; Zeng, Changqing ; Adhikari, Kaustubh ; Gallo, Carla ; Poletti, Giovanni ; Schuler-Faccini, Lavinia ; Bortolini, Maria-Cátira ; Canizales-Quinteros, Samuel ; Rothhammer, Francisco ; Bedoya, Gabriel ; González-José, Rolando ; Li, Hui ; Krutmann, Jean ; Liu, Fan ; Kayser, Manfred ; Ruiz-Linares, Andrés ; Tang, Kun ; Xu, Shuhua ; Zhang, Liang ; Jin, Li ; Wang, Sijia | Public Library of Science | 2018-11-30T03:10:47ZHair plays an important role in primates and is clearly subject to adaptive selection. While humans have lost most facial hair, eyebrows are a notable exception. Eyebrow thickness is heritable and widely believed to be subject to sexual selectio[...]![]()
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Pascoe, B. ; Schiaffino, F. ; Murray, S. ; Méric, G. ; Bayliss, S.C. ; Hitchings, M.D. ; Mourkas, E. ; Calland, J.K. ; Burga, R. ; Yori, P.P. ; Jolley, K.A. ; Cooper, K.K. ; Parker, C.T. ; Olortegui, M.P. ; Kosek, M.N. ; Sheppard, S.K. | Public Library of Science | 2020-12-14T16:10:02ZCampylobacter is the leading bacterial cause of gastroenteritis worldwide and its incidence is especially high in low-and middle-income countries (LMIC). Disease epidemiology in LMICs is different compared to high income countries like the USA o[...]![]()
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Pray, Ian-W. ; Swanson, Dallas-J. ; Ayvar, Viterbo ; Muro, Claudio ; Moyano, Luz-M. ; Gonzalez, Armando-E. ; Garcia, Hector-H. ; O'Neal, Seth-E. | Public Library of Science | 2019-02-06T14:45:58ZBACKGROUND: Taenia solium, a parasitic cestode that affects humans and pigs, is the leading cause of preventable epilepsy in the developing world. T. solium eggs are released into the environment through the stool of humans infected with an adul[...]![]()
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Olliaro, Piero ; Grogl, Max ; Boni, Marina ; Carvalho, Edgar M. ; Chebli, Houda ; Cissé, Mamoudou ; Diro, Ermias ; Cota, Gláucia Fernandes ; Erber, Astrid C. ; Gadisa, Endalamaw ; Handjani, Farhad ; Khamesipour, Ali ; Llanos-Cuentas, Alejandro ; Carvajal, Liliana López ; Grout, Lise ; Lmimouni, Badre Eddine ; Mokni, Mourad ; Nahzat, Mohammad Sami ; Salah, Afif Ben ; Ozbel, Yusuf ; Pascale, Juan Miguel ; Molina, Nidia Rizzo ; Rode, Joelle ; Romero, Gustavo ; Ruiz-Postigo, José Antonio ; Saravia, Nancy Gore ; Soto, Jaime ; Uzun, Soner ; Mashayekhi, Vahid ; Vélez, Ivan Dario ; Vogt, Florian ; Zerpa, Olga ; Arana, Byron | Public Library of Science | 2018-06-18T15:26:49ZIntroduction Progress with the treatment of cutaneous leishmaniasis (CL) has been hampered by inconsistent methodologies used to assess treatment effects. A sizable number of trials conducted over the years has generated only weak evidence backi[...]![]()
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Carrasco-Escobar, Gabriel ; Manrique, Edgar ; Ruiz-Cabrejos, Jorge ; Saavedra, Marlon ; Alava, Freddy ; Bickersmith, Sara ; Prussing, Catharine ; Vinetz, Joseph M. ; Conn, Jan E. ; Moreno, Marta ; Gamboa, Dionicia | Public Library of Science | 2019-07-04T17:00:15ZInterest in larval source management (LSM) as an adjunct intervention to control and eliminate malaria transmission has recently increased mainly because long-lasting insecticidal nets (LLINs) and indoor residual spray (IRS) are ineffective aga[...]![]()
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Carrasco-Escobar, G. ; Manrique, E. ; Ruiz-Cabrejos, J. ; Saavedra, M. ; Alava, F. ; Bickersmith, S. ; Prussing, C. ; Vinetz, J.M. ; Conn, J.E. ; Moreno, M. ; Gamboa, D. | Public Library of Science | 2019-12-06T20:57:45ZInterest in larval source management (LSM) as an adjunct intervention to control and eliminate malaria transmission has recently increased mainly because long-lasting insecticidal nets (LLINs) and indoor residual spray (IRS) are ineffective agai[...]![]()
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Moyano, Luz M. ; O'Neal, Seth E. ; Ayvar, Viterbo ; Gonzalvez, Guillermo ; Gamboa, Ricardo ; Vilchez, Percy ; Rodriguez, Silvia ; Reistetter, Joe ; Tsang, Victor C. W. ; Gilman, Robert H. ; Gonzalez, Armando E. ; Garcia, Hector H. | Public Library of Science | 2019-02-06T14:45:56ZBACKGROUND: Neurocysticercosis is a common helminthic infection of the central nervous system and an important cause of adult-onset epilepsy in endemic countries. However, few studies have examined associations between neurologic symptoms, serol[...]![]()
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Waltmann, Andreea ; Willcox, Alexandra C. ; Balasubramanian, Sujata ; Borrini Mayori, Katty ; Mendoza Guerrero, Sandra ; Salazar Sanchez, Renzo S. ; Roach, Jeffrey ; Condori Pino, Carlos ; Gilman, Robert H. ; Bern, Caryn ; Juliano, Jonathan J. ; Levy, Michael Z. ; Meshnick, Steven R. ; Bowman, Natalie M. | Public Library of Science | 2019-07-04T17:00:15ZTriatomine vectors transmit Trypanosoma cruzi, the etiological agent of Chagas disease in humans. Transmission to humans typically occurs when contaminated triatomine feces come in contact with the bite site or mucosal membranes. In the Souther[...]![]()
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Waltmann, A. ; Willcox, A.C. ; Balasubramanian, S. ; Borrini Mayori, K. ; Mendoza Guerrero, S. ; Salazar Sanchez, R.S. ; Roach, J. ; Condori Pino, C. ; Gilman, R.H. ; Bern, C. ; Juliano, J.J. ; Levy, M.Z. ; Meshnick, S.R. ; Bowman, N.M. | Public Library of Science | 2019-12-06T20:57:46ZTriatomine vectors transmit Trypanosoma cruzi, the etiological agent of Chagas disease in humans. Transmission to humans typically occurs when contaminated triatomine feces come in contact with the bite site or mucosal membranes. In the Southern[...]![]()
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Maco, Vicente ; Encalada, Mayling ; Wong, Carlos ; Marcos, Luis-A. | Public Library of Science | 2019-02-06T14:51:21Z![]()
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Bristow, Claire C. ; Kojima, Noah ; Lee, Sung-Jae ; Leon, Segundo R. ; Ramos, Lourdes B. ; Konda, Kelika A. ; Brown, Brandon ; Caceres, Carlos F. ; Klausner, Jeffrey D. | Public Library of Science | 2018-11-30T17:17:13ZBACKGROUND: Men who have sex with men (MSM) and transgender women in Peru are at high risk for acquiring syphilis and HIV infection. The World Health Organization highly recommends screening for HIV and syphilis to reduce morbidity and mortality[...]![]()
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Castillo-Neyra, Ricardo ; Barbu, Corentin M. ; Salazar, Renzo ; Borrini, Katty ; Náquira, César ; Levy, Michael Z. | Public Library of Science | 2019-02-06T14:53:10ZChagas disease affects millions of people in Latin America. The control of this vector-borne disease focuses on halting transmission by reducing or eliminating insect vector populations. Most transmission of Trypanosoma cruzi, the causative age[...]![]()
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Rosas-Aguirre, Angel ; Speybroeck, Niko ; Llanos-Cuentas, Alejandro ; Rosanas-Urgell, Anna ; Carrasco-Escobar, Gabriel ; Rodriguez, Hugo ; Gamboa, Dionicia ; Contreras-Mancilla, Juan ; Alava, Freddy ; Soares, Irene S. ; Remarque, Edmond ; D Alessandro, Umberto ; Erhart, Annette | Public Library of Science | 2019-02-06T14:53:10ZBACKGROUND: With low and markedly seasonal malaria transmission, increasingly sensitive tools for better stratifying the risk of infection and targeting control interventions are needed. A cross-sectional survey to characterize the current malar[...]![]()
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Blas, Magaly M. ; Brown, Brandon ; Menacho, Luis ; Alva, Isaac E. ; Silva-Santisteban, Alfonso ; Carcamo, Cesar | Public Library of Science | 2019-02-06T14:53:10ZBACKGROUND: Human Papilloma Virus (HPV) infection is the most common sexually transmitted viral infection worldwide. HPV is highly prevalent in sexually active men who have sex with men (MSM) and has been associated with anal cancer, penile can[...]