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Public Library of Science |
Documentos disponibles de esta editorial (243)
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Ding, Xavier C. ; Ade, Maria Paz ; Baird, J. Kevin ; Cheng, Qin ; Cunningham, Jane ; Dhorda, Mehul ; Drakeley, Chris ; Felger, Ingrid ; Gamboa, Dionicia ; Harbers, Matthias ; Herrera, Socrates ; Lucchi, Naomi ; Mayor, Alfredo ; Mueller, Ivo ; Sattabongkot, Jetsumon ; Ratsimbason, Arsene ; Richards, Jack ; Tanner, Marcel ; Gonzalez, Iveth J. | Public Library of Science | 2019-01-25T15:02:22ZThe global prevalence of malaria has decreased over the past fifteen years, but similar gains have not been realized against Plasmodium vivax because this species is less responsive to conventional malaria control interventions aimed principally[...]![]()
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Single, R.M. ; Meyer, D. ; Nunes, K. ; Francisco, R.S. ; Hünemeier, T. ; Maiers, M. ; Hurley, C.K. ; Bedoya, G. ; Gallo, C. ; Hurtado, A.M. ; Llop, E. ; Petzl-Erler, M.L. ; Poletti, G. ; Rothhammer, F. ; Tsuneto, L. ; Klitz, W. ; Ruiz-Linares, A. | Public Library of Science | 2020-12-14T16:10:14ZThe American continent was the last to be occupied by modern humans, and native populations bear the marks of recent expansions, bottlenecks, natural selection, and population substructure. Here we investigate how this demographic history has sh[...]![]()
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Paz-Soldan, Valerie-A. ; Yukich, Josh ; Soonthorndhada, Amara ; Giron, Maziel ; Apperson, Charles-S. ; Ponnusamy, Loganathan ; Schal, Coby ; Morrison, Amy-C. ; Keating, Joseph ; Wesson, Dawn-M. | Public Library of Science | 2019-02-06T14:45:57ZBACKGROUND: Dengue virus (and Chikungunya and Zika viruses) is transmitted by Aedes aegypti and Aedes albopictus mosquitoes and causes considerable human morbidity and mortality. As there is currently no vaccine or chemoprophylaxis to protect p[...]![]()
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Rowneki, M. ; Aronson, N. ; Du, P. ; Sachs, P. ; Blakemore, R. ; Chakravorty, S. ; Levy, S. ; Jones, A.L. ; Trivedi, G. ; Chebore, S. ; Addo, D. ; Byarugaba, D.K. ; Njobvu, P.D. ; Wabwire-Mangen, F. ; Erima, B. ; Ramos, E.S. ; Evans, C.A. ; Hale, B. ; Mancuso, J.D. ; Alland, D. | Public Library of Science | 2020-12-14T16:10:08ZBackground Drug susceptibility testing for Mycobacterium tuberculosis (MTB) is difficult to perform in resource-limited settings where Acid Fast Bacilli (AFB) smears are commonly used for disease diagnosis and monitoring. We developed a simple m[...]![]()
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Vargas-Cuentas, Natalia I. ; Roman-Gonzalez, Avid ; Gilman, Robert H. ; Barrientos, Franklin ; Ting, James ; Hidalgo, Daniela ; Jensen, Kelly ; Zimic, Mirko | Public Library of Science | 2019-01-25T15:18:33ZBACKGROUND: Autism spectrum disorder (ASD) currently affects nearly 1 in 160 children worldwide. In over two-thirds of evaluations, no validated diagnostics are used and gold standard diagnostic tools are used in less than 5% of evaluations. Cur[...]![]()
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Felgner, Jiin ; Jain, Aarti ; Nakajima, Rie ; Liang, Li ; Jasinskas, Algis ; Gotuzzo, Eduardo ; Vinetz, Joseph M. ; Miyajima, Fabio ; Pirmohamed, Munir ; Hassan-Hanga, Fatimah ; Umoru, Dominic ; Jibir, Binta Wudil ; Gambo, Safiya ; Olateju, Kudirat ; Felgner, Philip L. ; Obaro, Stephen ; Davies, D. Huw | Public Library of Science | 2019-01-25T15:18:33ZImproved serodiagnostic tests for typhoid fever (TF) are needed for surveillance, to facilitate patient management, curb antibiotic resistance, and inform public health programs. To address this need, IgA, IgM and IgG ELISAs using Salmonella ent[...]![]()
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De Los Angeles Lazo, M. ; Bernabé-Ortiz, A. ; Pinto, M.E. ; Ticse, R. ; Malaga, G. ; Sacksteder, K. ; Miranda, J.J. ; Gilman, R.H. | Public Library of Science | 2020-06-10T18:12:17ZAim: We aimed to estimate the morbidity rate and associated factors for diabetic peripheral neuropathy (DPN) in a low-middle income country setting. Methods: Cross-sectional study, data was gathered at Peru's Ministry of Health national speciali[...]![]()
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Lazo, Maria de los Angeles ; Bernabé-Ortiz, Antonio ; Pinto, Miguel E. ; Ticse, Ray ; Malaga, German ; Sacksteder, Katherine ; Miranda, J. Jaime ; Gilman, Robert H. | Public Library of Science | 2020-06-10T18:12:17ZAIM: We aimed to estimate the morbidity rate and associated factors for diabetic peripheral neuropathy (DPN) in a low-middle income country setting. METHODS: Cross-sectional study, data was gathered at Peru's Ministry of Health national special[...]![]()
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Zhong, Q.Y. ; Gelaye, B. ; Zaslavsky, A.M. ; Fann, J.R. ; Rondon, M.B. ; Sánchez, S.E. ; Williams, M.A. | Public Library of Science | 2019-04-24T18:23:57ZObjective: Generalized anxiety disorder (GAD) during pregnancy is associated with several adverse maternal and perinatal outcomes. A reliable and valid screening tool for GAD should lead to earlier detection and treatment. Among pregnant Peruvia[...]![]()
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Berry, Alexander S. F. ; Salazar-Sanchez, Renzo ; Castillo-Neyra, Ricardo ; Borrini-Mayori, Katty ; Arevalo-Nieto, Claudia ; Chipana-Ramos, Claudia ; Vargas-Maquera, Melina ; Ancca-Juarez, Jenny ; Naquira-Velarde, Cesar ; Levy, Michael Z. ; Brisson, Dustin | Public Library of Science | 2020-07-14T00:00:57ZAnthropogenic environmental alterations such as urbanization can threaten native populations as well as create novel environments that allow human pests and pathogens to thrive. As the number and size of urban environments increase globally, it [...]![]()
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Zorrilla, Victor ; De Los Santos, Maxy B. ; Espada, Liz ; Santos, Rocío Del Pilar ; Fernández, Roberto ; Urquia, Albino ; Stoops, Craig A. ; Ballard, Sarah-Blythe ; Lescano, Andres G. ; Vásquez, Gissella M. ; Valdivia, Hugo O. | Public Library of Science | 2019-01-25T15:18:33ZBACKGROUND: Cutaneous leishmaniasis (CL) is an important health problem in the New World affecting civilian and military populations that are frequently exposed in endemic settings. The Peruvian region of Madre de Dios located near the border wi[...]![]()
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Buffarini, Romina ; Restrepo-Mendez, Maria-Clara ; Silveira, Vera-M. ; Miranda, Jaime-J. ; Goncalves, Helen-D. ; Oliveira, Isabel-O. ; Horta, Bernardo-L. ; Gigante, Denise-P. ; Menezes, Ana-Maria ; Assuncao, Maria-Cecilia-F. | Public Library of Science | 2019-02-06T14:45:11ZAIM: Glycated haemoglobin (HbA1c), a marker of glucose control in individuals with diabetes mellitus, is also related with the incidence of cardiometabolic risk in populations free of disease. The aim of this study was to describe the distributi[...]![]()
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Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites.
Knuepfer, Ellen ; Wright, Katherine E. ; Kumar Prajapati, Surendra ; Rawlinson, Thomas A. ; Mohring, Franziska ; Koch, Marion ; Lyth, Oliver R. ; Howell, Steven A. ; Villasis, Elizabeth ; Snijders, Ambrosius P. ; Moon, Robert W. ; Draper, Simon J. ; Rosanas-Urgell, Anna ; Higgins, Matthew K. ; Baum, Jake ; Holder, Anthony A. | Public Library of Science | 2019-12-06T21:02:54ZMalaria is caused by Plasmodium parasites, which invade and replicate in erythrocytes. For Plasmodium falciparum, the major cause of severe malaria in humans, a heterotrimeric complex comprised of the secreted parasite proteins, PfCyRPA, PfRIPR [...]![]()
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Knuepfer, Ellen ; Wright, Katherine E. ; Kumar Prajapati, Surendra ; Rawlinson, Thomas A. ; Mohring, Franziska ; Koch, Marion ; Lyth, Oliver R. ; Howell, Steven A. ; Villasis, Elizabeth ; Snijders, Ambrosius P. ; Moon, Robert W. ; Draper, Simon J. ; Rosanas-Urgell, Anna ; Higgins, Matthew K. ; Baum, Jake ; Holder, Anthony A. | Public Library of Science | 2019-07-04T16:59:29ZMalaria is caused by Plasmodium parasites, which invade and replicate in erythrocytes. For Plasmodium falciparum, the major cause of severe malaria in humans, a heterotrimeric complex comprised of the secreted parasite proteins, PfCyRPA, PfRIPR [...]![]()
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Shah, Jyotsna ; Weltman, Helena ; Narciso, Patricia ; Murphy, Christina ; Poruri, Akhila ; Baliga, Shrikala ; Sharon, Leesha ; York, Mary ; Cunningham, Gail ; Miller, Steve ; Caviedes, Luz ; Gilman, Robert ; Desmond, Edward ; Ramasamy, Ranjan | Public Library of Science | 2019-01-25T15:18:33ZTwo rapid dual color fluorescence in situ hybridization (FISH) assays were evaluated for detecting M. tuberculosis and related pathogens in cultures. The MN Genus-MTBC FISH assay uses an orange fluorescent probe specific for the Mycobacterium tu[...]![]()
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Planas, Maria-Elena ; García, Patricia J. ; Bustelo, Monserrat ; Carcamo, Cesar P. ; Martinez, Sebastian ; Nopo, Hugo ; Rodríguez, Julio ; Merino, Maria-Fernanda ; Morrison, Andrew | Public Library of Science | 2019-02-06T14:53:12ZMost studies reporting ethnic disparities in the quality of healthcare come from developed countries and rely on observational methods. We conducted the first experimental study to evaluate whether health providers in Peru provide differential [...]![]()
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Huicho, Luis ; Huayanay-Espinoza, Carlos A. ; Hernandez, Patricia ; Niño de Guzman, Jessica ; Rivera-Ch, Maria | Public Library of Science | 2018-11-30T03:10:45ZWe compared expenditure trends for reproductive, maternal, neonatal and child health (RMNCH) with trends in RMNCH service coverage in Peru. We used National Health Accounts data to report on total health expenditure by source; the Countdown data[...]![]()
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Franco-Paredes, Carlos ; Khan, M. Imran ; Gonzalez-Diaz, Esteban ; Santos-Preciado, Jose-I. ; Rodriguez-Morales, Alfonso-J. ; Gotuzzo, Eduardo | Public Library of Science | 2019-02-06T14:51:19Z![]()
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Ballard, Sarah-Blythe ; Reaves, Erik J. ; Luna, C. Giannina ; Silva, Maria E. ; Rocha, Claudio ; Heitzinger, Kristen ; Saito, Mayuko ; Apaza, Sonia ; Espetia, Susan ; Blazes, David L. ; Tilley, Drake H. ; Guzman Aguilar, Rene C. ; Gilman, Robert H. ; Bausch, Daniel G. | Public Library of Science | 2019-02-06T14:53:10ZBACKGROUND: Successful vaccination strategies against norovirus will require understanding the burden of disease and relevant genotypes in populations. However, few data are available from cohort studies of adults living in low- and middle-inco[...]![]()
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Barbosa, Susana ; Gozze, Amanda B. ; Lima, Nathalia F. ; Batista, Camilla L. ; Bastos, Melissa da Silva ; Nicolete, Vanessa C. ; Fontoura, Pablo S. ; Goncalves, Raquel M. ; Viana, Susana Ariane S. ; Menezes, Maria Jose ; Scopel, Kezia Katiani G. ; Cavasini, Carlos E. ; Malafronte, Rosely dos Santos ; da Silva-Nunes, Monica ; Vinetz, Joseph M. ; Castro, Marcia C. ; Ferreira, Marcelo U. | Public Library of Science | 2020-06-10T18:12:16ZBACKGROUND: New frontier settlements across the Amazon Basin pose a major challenge for malaria elimination in Brazil. Here we describe the epidemiology of malaria during the early phases of occupation of farming settlements in Remansinho area, [...]![]()
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Miranda, J. Jaime ; Lopez-Rivera, Luis A. ; Quistberg, D. Alex ; Rosales-Mayor, Edmundo ; Gianella, Camila ; Paca-Palao, Ada ; Luna, Diego ; Huicho, Luis ; Paca, Ada | Public Library of Science | 2020-06-10T18:12:18ZBACKGROUND: The epidemiological profile and trends of road traffic injuries (RTIs) in Peru have not been well-defined, though this is a necessary step to address this significant public health problem in Peru. The objective of this study was to [...]![]()
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Metcalf, Tatiana ; Soria, Jaime ; Montano, Silvia M. ; Ticona, Eduardo ; Evans, Carlton A. ; Huaroto, Luz ; Kasper, Matthew ; Ramos, Eric S. ; Mori, Nicanor ; Jittamala, Podjanee ; Chotivanich, Kesinee ; Chavez, Irwin F. ; Singhasivanon, Pratap ; Pukrittayakamee, Sasithon ; Zunt, Joseph R. | Public Library of Science | 2018-11-30T03:10:46ZBACKGROUND: Meningitis caused by Mycobacterium tuberculosis is a major cause of morbidity and mortality worldwide. We evaluated the performance of cerebrospinal fluid (CSF) testing with the GeneXpert MTB/RIF assay versus traditional approaches f[...]![]()
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Mekonnen, B. ; Mihret, A. ; Getahun, M. ; Hailu, T. ; Sidiki, S. ; Kelley, H.V. ; Scordo, J.M. ; Hunt, W.G. ; Pan, X. ; Balada-Llasat, J.-M. ; Gebreyes, W. ; Evans, C.A. ; Aseffa, A. ; Torrelles, J.B. ; Wang, S.-H. ; Abebe, T. | Public Library of Science | 2019-07-04T16:59:34ZTimely diagnosis of tuberculosis (TB) is limited in Ethiopia. We evaluated the performance of a low technology, thin layer agar, Mycobacterium tuberculosis (M.tb) culture color plate (TB-CX) test with concurrent drug susceptibility testing (DST)[...]![]()
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Marzal, Miguel ; Guerra-Giraldez, Cristina ; Paredes, Adriana ; Cangalaya, Carla ; Rivera, Andrea ; Gonzalez, Armando E. ; Mahanty, Siddhartha ; Garcia, Hector H. ; Nash, Theodore E. | Public Library of Science | 2020-06-10T18:12:17ZCysticidal drug treatment of viable Taenia solium brain parenchymal cysts leads to an acute pericystic host inflammatory response and blood brain barrier breakdown (BBB), commonly resulting in seizures. Naturally infected pigs, untreated or trea[...]![]()
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Bernabé-Ortiz, Antonio ; Ruiz-Alejos, Andrea ; Miranda, J. Jaime ; Mathur, Rohini ; Perel, Pablo ; Smeeth, Liam | Public Library of Science | 2019-01-25T15:18:34ZOBJECTIVES: The EZSCAN is a non-invasive device that, by evaluating sweat gland function, may detect subjects with type 2 diabetes mellitus (T2DM). The aim of the study was to conduct a systematic review and meta-analysis including studies asses[...]