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Public Library of Science |
Documentos disponibles de esta editorial (243)
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Serra-Casas, Elisa ; Manrique, Paulo ; Ding, Xavier C. ; Carrasco-Escobar, Gabriel ; Alava, Freddy ; Gave, Anthony ; Rodriguez, Hugo ; Contreras-Mancilla, Juan ; Rosas-Aguirre, Angel ; Speybroeck, Niko ; Gonzalez, Iveth J. ; Rosanas-Urgell, Anna ; Gamboa, Dionicia | Public Library of Science | 2019-01-25T15:28:05ZBACKGROUND: Loop-mediated isothermal DNA amplification (LAMP) methodology offers an opportunity for point-of-care (POC) molecular detection of asymptomatic malaria infections. However, there is still little evidence on the feasibility of impleme[...]![]()
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Clouse, K. ; Blevins, M. ; Lindegren, M.L. ; Yotebieng, M. ; Nguyen, D.T. ; Omondi, A. ; Michael, D. ; Zannou, D.M. ; Carriquiry, G. ; Pettit, A. ; IeDEA ; Gotuzzo, E. ; Mejia, F. ; Carriquiry, G. | Public Library of Science | 2019-04-24T18:23:56ZObjective: Xpert MTB/RIF is recommended by the World Health Organization (WHO) as the initial tuberculosis (TB) diagnostic test in individuals suspected of HIV-associated TB. We sought to evaluate field implementation of Xpert among a cohort of [...]![]()
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Jara, Marlene ; Berg, Maya ; Caljon, Guy ; de Muylder, Geraldine ; Cuypers, Bart ; Castillo, Denis ; Maes, Ilse ; Orozco, María Del Carmen ; Vanaerschot, Manu ; Dujardin, Jean-Claude ; Arevalo, Jorge | Public Library of Science | 2019-01-25T15:28:05ZIt was recently hypothesized that Leishmania amastigotes could constitute a semi-quiescent stage characterized by low replication and reduced metabolic activity. This concept developed with Leishmania (Leishmania) mexicana and Leishmania (Leishm[...]![]()
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Prussing, Catharine ; Saavedra, Marlon P. ; Bickersmith, Sara A. ; Alava, Freddy ; Guzman, Mitchel ; Manrique, Edgar ; Carrasco-Escobar, Gabriel ; Moreno, Marta ; Gamboa, Dionicia ; Vinetz, Joseph M. ; Conn, Jan E. | Public Library of Science | 2019-07-04T17:00:18ZIn Amazonian Peru, the primary malaria vector, Nyssorhynchus darlingi (formerly Anopheles darlingi), is difficult to target using standard vector control methods because it mainly feeds and rests outdoors. Larval source management could be a use[...]![]()
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Prussing, C. ; Saavedra, M.P. ; Bickersmith, S.A. ; Alava, F. ; Guzmán, M. ; Manrique, E. ; Carrasco-Escobar, G. ; Moreno, M. ; Gamboa, D. ; Vinetz, J.M. ; Conn, J.E. | Public Library of Science | 2019-12-06T20:57:51ZIn Amazonian Peru, the primary malaria vector, Nyssorhynchus darlingi (formerly Anopheles darlingi), is difficult to target using standard vector control methods because it mainly feeds and rests outdoors. Larval source management could be a use[...]![]()
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Alva, Alicia ; Cangalaya, Carla ; Quiliano, Miguel ; Krebs, Casey ; Gilman, Robert H. ; Sheen, Patricia ; Zimic, Mirko | Public Library of Science | 2019-01-25T15:28:05ZParasitic infections are generally diagnosed by professionals trained to recognize the morphological characteristics of the eggs in microscopic images of fecal smears. However, this laboratory diagnosis requires medical specialists which are lac[...]![]()
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Errea, Renato A. ; Vasquez-Rios, George ; Machicado, Jorge D. ; Gallardo, Maria Susana ; Cornejo, Marilhia ; Urquiaga, Jorge F. ; Montoya, Diego ; Zamudio, Rodrigo ; Terashima, Angélica ; Marcos, Luis A. ; Samalvides, Frine | Public Library of Science | 2019-02-06T14:53:09ZIn developing countries, education to health-care professionals is a cornerstone in the battle against neglected tropical diseases (NTD). Studies evaluating the level of knowledge of medical students in clinical and socio-demographic aspects o[...]![]()
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Valenciano, Alberto ; Baskin, Jon A. ; Abella, Juan ; Pérez-Ramos, Alejandro ; Ángeles Álvarez-Sierra, Ángeles ; Morales, Jorge ; Hartstone-Rose, Adam | Public Library of Science | 2016-04We describe cranial and mandibular remains of three undescribed individuals of the giant mustelid Megalictis ferox Matthew, 1907 from the latest Arikareean (Ar4), Early Miocene mammal fauna of Nebraska, and Wyoming (USA) housed at the American M[...]![]()
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Benziger, Catherine P. ; Bernabé-Ortiz, Antonio ; Gilman, Robert H. ; Checkley, William ; Smeeth, Liam ; Malaga, German ; Miranda, J. Jaime | Public Library of Science | 2019-02-06T14:53:10ZOBJECTIVE: We aimed to characterize metabolic status by body mass index (BMI) status. METHODS: The CRONICAS longitudinal study was performed in an age-and-sex stratified random sample of participants aged 35 years or older in four Peruvian set[...]![]()
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Guevara, Govinda ; Olortegui Flores, Yamileth ; Fernández de las Heras, Laura ; Perera González, Julián ; Navarro LLorens, Juana María | Public Library of Science | 2019-07-26Rhodococcus ruber Chol-4 is a potent steroid degrader that has a great potential as a biotechnological tool. As proof of concept, this work presents testosterone production from 4- androstene-3,17-dione by tailoring innate catabolic enzymes of t[...]![]()
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Faggion, C. M. ; Apaza, K. ; Ariza-Fritas, T. ; Malaga, L. ; Giannakopoulos, N. N. ; Alarcon, M. A. | Public Library of Science | 2019-01-25T16:36:29ZBackground Consensus guidelines are useful to improve clinical decision making. Therefore, the methodological evaluation of these guidelines is of paramount importance. Low quality information may guide to inadequate or harmful clinical decision[...]![]()
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Oriol-Tordera, B. ; Berdasco, M. ; Llano, A. ; Mothe, B. ; Gálvez, C. ; Martinez-Picado, J. ; Carrillo, J. ; Blanco, J. ; Duran-Castells, C. ; Ganoza, C. ; Sánchez, J. ; Clotet, B. ; Calle, M.L. ; Sánchez-Pla, A. ; Esteller, M. ; Brander, C. ; Ruiz-Riol, M. | Public Library of Science | 2020-12-14T16:10:02ZGWAS, immune analyses and biomarker screenings have identified host factors associated with in vivo HIV-1 control. However, there is a gap in the knowledge about the mechanisms that regulate the expression of such host factors. Here, we aimed to[...]![]()
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Vasquez, Ana L. ; Errea, Renato A. ; Hoces, Daniel ; Echevarria, Juan ; González-Lagos, Elsa ; Gotuzzo, Eduardo | Public Library of Science | 2019-01-25T15:28:06ZINTRODUCTION: Based on the hypothesis that HIV programs struggle to deliver health services that harmonize necessities of treatment and prevention, we described the outcomes of routinely provided HIV testing to partners of people living with HIV[...]![]()
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Torres-Roman, J. Smith ; Cruz-Avila, Yuridia ; Suarez-Osorio, Karina ; Arce-Huamaní, Miguel Ángel ; Menez-Sanchez, Alejandra ; Aveiro-Róbalo, Telmo Raúl ; Mejia, Christian R. ; Ruiz, Eloy F. | Public Library of Science | 2018-11-30T17:17:16ZINTRODUCTION: Motivation in medical students is positively associated with learning strategies. However, the evidence of a direct relationship between motivation and performance is vague. The objective of this study is to determine if the motiva[...]![]()
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Rodríguez, L. ; Bustamante, B. ; Huaroto, L. ; Agurto, C. ; Illescas, R. ; Ramírez, R. ; Diaz, A. ; Hidalgo, J. | Public Library of Science | 2019-01-25T16:36:29ZBackground The incidence of candidemia is increasing in developing countries. Very little is known about the epidemiology of candidemia in Peru. The aim of this study is to describe the incidence, microbiology, clinical presentation and outcomes[...]![]()
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Zavaleta, Carol ; Berrang-Ford, Lea ; Ford, James ; Llanos-Cuentas, Alejandro ; Carcamo, Cesar ; Ross, Nancy A. ; Lancha, Guillermo ; Sherman, Mya ; Harper, Sherilee L. ; Edge, Victoria ; Lwasa, Shuaib ; Namanya, Didacus B. | Public Library of Science | 2018-11-08T19:39:21ZBackground Climate change is affecting food systems globally, with implications for food security, nutrition, and the health of human populations. There are limited data characterizing the current and future consequences of climate change on loc[...]![]()
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Cura, Carolina I. ; Duffy, Tomas ; Lucero, Raul H. ; Bisio, Margarita ; Peneau, Julie ; Jimenez-Coello, Matilde ; Calabuig, Eva ; Gimenez, Maria J. ; Valencia Ayala, Edward ; Kjos, Sonia A. ; Santalla, Jose ; Mahaney, Susan M. ; Cayo, Nelly M. ; Nagel, Claudia ; Barcan, Laura ; Malaga Machaca, Edith S. ; Acosta Viana, Karla Y. ; Brutus, Laurent ; Ocampo, Susana B. ; Aznar, Christine ; Cuba Cuba, Cesar A. ; Gurtler, Ricardo E. ; Ramsey, Janine M. ; Ribeiro, Isabela ; VandeBerg, John L. ; Yadon, Zaida E. ; Osuna, Antonio ; Schijman, Alejandro G. | Public Library of Science | 2019-02-06T14:53:10ZBACKGROUND: Trypanosoma cruzi has been classified into six Discrete Typing Units (DTUs), designated as TcI-TcVI. In order to effectively use this standardized nomenclature, a reproducible genotyping strategy is imperative. Several typing scheme[...]![]()
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Moyano, Luz M. ; Saito, Mayuko ; Montano, Silvia M. ; Gonzalvez, Guillermo ; Olaya, Sandra ; Ayvar, Viterbo ; Gonzalez, Isidro ; Larrauri, Luis ; Tsang, Victor C. W. ; Llanos, Fernando ; Rodriguez, Silvia ; Gonzalez, Armando E. ; Gilman, Robert H. ; Garcia, Hector H. | Public Library of Science | 2020-06-10T18:12:16ZBACKGROUND: The prevalence of epilepsy added to inadequate treatment results in chronic morbidity and considerable mortality in poor populations. Neurocysticercosis (NCC), a helminthic disease of the central nervous system, is a leading cause o[...]![]()
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Pesantes, M.A. ; Moyano, L.M. ; Sommerville, C. ; Cysticercosis Working Group in Peru COHESION Project | Public Library of Science | 2020-12-14T16:10:04ZBackground Neurocysticercosis (NCC) is a helminthic disease of the central nervous system, and it is one of the leading causes of seizures and symptomatic epilepsy in countries with tropical regions like Peru. Studies of people with epilepsy in [...]![]()
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Ong, Catherine W. M. ; Elkington, Paul T. ; Brilha, Sara ; Ugarte-Gil, Cesar ; Tome-Esteban, Maite T. ; Tezera, Liku B. ; Pabisiak, Przemyslaw J. ; Moores, Rachel C. ; Sathyamoorthy, Tarangini ; Patel, Vimal ; Gilman, Robert H. ; Porter, Joanna C. ; Friedland, Jon S. | Public Library of Science | 2019-02-06T14:53:12ZPulmonary cavities, the hallmark of tuberculosis (TB), are characterized by high mycobacterial load and perpetuate the spread of M. tuberculosis. The mechanism of matrix destruction resulting in cavitation is not well defined. Neutrophils are e[...]![]()
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Arriola, Carmen S. ; Gonzalez, Armando E. ; Gomez-Puerta, Luis A. ; Lopez-Urbina, Maria T. ; Garcia, Hector H. ; Gilman, Robert H. | Public Library of Science | 2020-06-10T18:12:17ZTaenia solium infection causes severe neurological disease in humans. Even though infection and exposure to swine cysticercosis is scattered throughout endemic villages, location of the tapeworm only explains some of the nearby infections and is[...]![]()
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Limaye, Neha P. ; Rivas-Nieto, Andrea C. ; Carcamo, Cesar P. ; Blas, Magaly M. | Public Library of Science | 2018-11-30T22:50:34ZBACKGROUND: In rural areas of the Loreto region within the Peruvian Amazon, maternal mortality rate is above the national average and the majority of women deliver at home without care from a trained health care provider. METHODS: To develop com[...]![]()
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Loret de Mola, Christian ; Quispe, Renato ; Valle, Giancarlo A. ; Poterico, Julio A. | Public Library of Science | 2020-06-10T18:12:17ZBACKGROUND: Rapid urbanization, increase in food availability, and changes in diet and lifestyle patterns have been changing nutritional profiles in developing nations. We aimed to describe nutritional changes in children under 5 years and women[...]![]()
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Flores-Flores, Oscar ; Bell, Ruth ; Reynolds, Rodney ; Bernabé-Ortiz, Antonio | Public Library of Science | 2019-03-05T15:23:30ZBACKGROUND: Disability rates increase with age. In 2012, Peruvian older adults (> /= 65 years) represented 9% of the population. Additionally, older population reported disabilities at about 5 times the rate of Peruvians between 36 and 64 years [...]![]()
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Datta, S. ; Alvarado, K. ; Gilman, R.H. ; Valencia, T. ; Aparicio, C. ; Ramos, E.S. ; Montoya, R. ; Evans, C.A. | Public Library of Science | 2019-12-06T21:04:41ZBackground Assessing Mycobacterium tuberculosis (TB) viability by fluorescein diacetate (FDA) microscopy can predict TB culture results, treatment response and infectiousness. However, diverse methods have been published. We aimed to optimise FD[...]