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Documentos disponibles de esta editorial (243)
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Boussau, Bastien ; Walton, Zaak ; Delgado Sáez, Juan Antonio ; Collantes, Francisco ; Beani, Laura ; Stewart, Isaac J. ; Cameron, Sydney A. ; Whitfield, James B. ; Johnston, J. Spencer ; Holland, Peter W.H. ; Bachtrog, Doris ; Kathirithamby, Jeyaraney ; Huelsenbeck, John P. | Public Library of Science | 2014-10-01Insect phylogeny has recently been the focus of renewed interest as advances in sequencing techniques make it possible to rapidly generate large amounts of genomic or transcriptomic data for a species of interest. However, large numbers of marke[...]![]()
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Lorenzo Bermejo, Justo ; Boekstegers, Felix ; González Silos, Rosa ; Marcelain, Katherine ; Baez Benavides, Pablo ; Barahona Ponce, Carol ; Müller, Bettina ; Ferreccio, Catterina ; Koshiol, Jill ; Fischer, Christine ; Peil, Barbara ; Sinsheimer, Janet ; Fuentes Guajardo, Macarena ; Barajas, Olga ; González-José, Rolando ; Bedoya, Gabriel ; Catira Bortolini, Maria ; Canizales-Quinteros, Samuel ; Gallo, Carla ; Ruiz Linares, Andres ; Rothhammer, Francisco | Public Library of Science | 2019-01-25T16:03:21ZLatin Americans are highly heterogeneous regarding the type of Native American ancestry. Consideration of specific associations with common diseases may lead to substantial advances in unraveling of disease etiology and disease prevention. Here [...]![]()
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Corzo-Leon, Dora E. ; Alvarado-Matute, Tito ; Colombo, Arnaldo L. ; Cornejo-Juarez, Patricia ; Cortes, Jorge ; Echevarria, Juan I. ; Guzman-Blanco, Manuel ; Macias, Alejandro E. ; Nucci, Marcio ; Ostrosky-Zeichner, Luis ; Ponce-de-Leon, Alfredo ; Queiroz-Telles, Flavio ; Santolaya, Maria E. ; Thompson-Moya, Luis ; Tiraboschi, Iris N. ; Zurita, Jeannete ; Sifuentes-Osornio, Jose | Public Library of Science | 2020-06-10T18:12:18ZINTRODUCTION: Larger populations at risk, broader use of antibiotics and longer hospital stays have impacted on the incidence of Candida sp. bloodstream infections (CBSI). OBJECTIVE: To determine clinical and epidemiologic characteristics of pat[...]![]()
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Halsey, Eric-S. ; Baldeviano, G. Christian ; Edgel, Kimberly-A. ; Vilcarromero, Stalin ; Sihuincha, Moises ; Lescano, Andres-G. | Public Library of Science | 2019-02-06T14:45:35ZBACKGROUND: Malaria and dengue are two of the most common vector-borne diseases in the world, but co-infection is rarely described, and immunologic comparisons of co-infection with mono-infection are lacking. METHODOLOGY AND PRINCIPAL FINDINGS: [...]![]()
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Debacq, Gabrielle ; Moyano, Luz M. ; Garcia, Hector H. ; Boumediene, Farid ; Marin, Benoit ; Ngoungou, Edgard B. ; Preux, Pierre-Marie | Public Library of Science | 2019-01-25T16:03:21ZBACKGROUND: We reviewed studies that analyzed cysticercosis (CC), neurocysticercosis (NCC) and epilepsy across Latin America, Asia and Sub-Saharan Africa, to estimate the odds ratio and etiologic fraction of epilepsy due to CC in tropical region[...]![]()
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Watts, Nathaniel S. ; Pajuelo, Monica ; Clark, Taryn ; Loader, Maria-Cristina I. ; Verastegui, Manuela R. ; Sterling, Charles ; Friedland, Jon S. ; Garcia, Hector H. ; Gilman, Robert H. | Public Library of Science | 2020-06-10T18:12:20ZBACKGROUND: Neurocysticercosis is a leading cause of seizures and epilepsy in most of the world, and it occurs when Taenia solium larval cysts infect the central nervous system. T. solium tapeworm infection is endemic in much of Peru, but there[...]![]()
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Martinez, D. Y. ; Verdonck, K. ; Kaye, P. M. ; Adaui, Vanessa ; Polman, K. ; Llanos-Cuentas, A. ; Dujardin, J. ; Boelaert, M. | Public Library of Science | 2018-03-22T23:38:49ZInfectious diseases are often studied one by one, but people can have more than one infection at the same time. This is likely to happen when different microorganisms are linked to specific geographical regions or living conditions. In this pape[...]![]()
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Chambergo-Michilot, Diego ; Tellez, Walter Andree ; Becerra-Chauca, Naysha ; Zafra-Tanaka, Jessica Hanae ; Taype-Rondan, Álvaro | Public Library of Science | 2020-07-14T00:01:03ZBackground: Excessive exposure to ultraviolet radiation increases the risk of skin cancer and other conditions. SMS text reminders may be a useful tool to improve sun protection habits due to its massive reach, low cost, and accessibility. Objec[...]![]()
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Marín Aguacil, Arturo ; Tejero Franco, Héctor ; Nuño Sanz, Juan Carlos ; Montero Carnerero, Francisco | Public Library of Science | 2013-12We study the evolution of a finite size population formed by mutationally isolated lineages of error-prone replicators in a two-peak fitness landscape. Computer simulations are performed to gain a stochastic description of the system dynamics. M[...]![]()
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Limaye, Neha P. ; Blas, Magaly M. ; Alva, Isaac E. ; Carcamo, Cesar P. ; García, Patricia J. | Public Library of Science | 2018-11-30T23:41:29ZThe Loreto region of the Peruvian Amazon faces many obstacles to health care delivery. The majority of the population is river-bound and lives below the poverty line, with some of the worst health indicators in Peru. To overcome these barriers a[...]![]()
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Grandjean, Louis ; Iwamoto, Tomotada ; Lithgow, Anna ; Gilman, Robert H. ; Arikawa, Kentaro ; Nakanishi, Noriko ; Martin, Laura ; Castillo, Edith ; Alarcon, Valentina ; Coronel, Jorge ; Solano, Walter ; Aminian, Minoo ; Guezala, Claudia ; Rastogi, Nalin ; Couvin, David ; Sheen, Patricia ; Zimic, Mirko ; Moore, David A. J. | Public Library of Science | 2019-02-06T14:53:10ZBACKGROUND: The comparison of Mycobacterium tuberculosis bacterial genotypes with phenotypic, demographic, geospatial and clinical data improves our understanding of how strain lineage influences the development of drug-resistance and the sprea[...]![]()
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Belter, Christopher W. ; García, Patricia J. ; Livinski, Alicia A. ; Leon-Velarde, Fabiola ; Weymouth, Kristen H. ; Glass, Roger I. | Public Library of Science | 2019-12-06T21:02:56ZOBJECTIVE: In Peru, the past three decades have witnessed impressive growth in biomedical research catalyzed from a single research university and its investigators who secured international partnerships and funding. We conducted a bibliometric[...]![]()
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Belter, Christopher W. ; García, Patricia J. ; Livinski, Alicia A. ; Leon-Velarde, Fabiola ; Weymouth, Kristen H. ; Glass, Roger I. | Public Library of Science | 2019-08-08T15:23:47ZOBJECTIVE: In Peru, the past three decades have witnessed impressive growth in biomedical research catalyzed from a single research university and its investigators who secured international partnerships and funding. We conducted a bibliometric[...]![]()
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Carrillo-Larco, R.M. ; Bennett, J.E. ; Cesare, M.D. ; Gregg, E.W. ; Bernabé-Ortiz, A. | Public Library of Science | 2020-12-14T16:06:15ZBackground: Non-communicable diseases (NCDs) have received political attention and commitment, yet surveillance is needed to measure progress and set priorities. Building on global estimates suggesting that Peru is not on target to meet the Sust[...]![]()
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Prieto, Daniel ; Román, Elvira ; Correia, C. Inês Ribeiro ; Pla, Jesús | Public Library of Science | 2014-01-27The opportunistic pathogen Candida albicans is a frequent inhabitant of the human gastrointestinal tract where it usually behaves as a harmless commensal. In this particular niche, it needs to adapt to the different micro environments that chall[...]![]()
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Lenhart, Audrey ; Morrison, Amy C. ; Paz-Soldan, Valerie A. ; Forshey, Brett M. ; Cordova-Lopez, Jhonny J. ; Astete, Helvio ; Elder, John P. ; Sihuincha, Moises ; Gotlieb, Esther E. ; Halsey, Eric S. ; Kochel, Tadeusz J. ; Scott, Thomas W. ; Alexander, Neal ; McCall, Philip J. | Public Library of Science | 2020-07-14T00:02:31ZDengue is one of the most important vector-borne diseases, resulting in an estimated hundreds of millions of infections annually throughout the tropics. Control of dengue is heavily dependent upon control of its primary mosquito vector, Aedes ae[...]![]()
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Martín Forés, Irene ; Acosta Gallo, Belén ; Castro Parga, Isabel ; Miguel Garcinuño, José Manuel de ; Pozo Lira, Alejandro del ; Casado González, Miguel Ángel | Public Library of Science | 2018-06-14Scientists have been interested in many topics driven by biological invasions, such as shifts in the area of distribution of plant species and rapid evolution. Invasiveness of exotic plant species depends on variations on morphological and repro[...]![]()
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Román González, Elvira ; Alonso Monge, Rebeca ; Miranda, Alberto ; Pla Alonso, Jesús | Public Library of Science | 2015-07-21The cell wall integrity pathway (CWI) plays an important role in the biogenesis of the cell wall in Candida albicans and other fungi. In the present work, the C. albicans MKK2 gene that encodes the putative MAPKK of this pathway was deleted in d[...]![]()
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Merino, José Joaquín ; Arce, Carmen ; Naddaf, Ahmad ; Bellver Landete, Víctor ; González, María Pilar ; Oset Gasque, María Jesús | Public Library of Science | 2014Background: The discovery that nitric oxide (NO)functions as a signalling molecule in the nervous system has radically changed the concept of neuronal communication. NO induces the release of amino acid neurotransmitters but the underlying mecha[...]![]()
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Daivadanam, M. ; Ingram, M. ; Annerstedt, K.S. ; Parker, G. ; Bobrow, K. ; Dolovich, L. ; Gould, G. ; Riddell, M. ; Vedanthan, R. ; Webster, J. ; Absetz, P. ; Alvesson, H.M. ; Androutsos, O. ; Chavannes, N. ; Cortez, B. ; Devarasetty, P. ; Fottrell, E. ; Gonzalez-Salazar, F. ; Goudge, J. ; Herasme, O. ; Jennings, H. ; Kapoor, D. ; Kamano, J. ; Kasteleyn, M. ; Kyriakos, C. ; Manios, Y. ; Mogulluru, K. ; Owolabi, M. ; Lazo-Porras, M. ; Silva, W. ; Thrift, A. ; Uvere, E. ; Webster, R. ; Van Der Kleij, R. ; Van Olmen, J. ; Vardavas, C. ; Zhang, P. | Public Library of Science | 2019-12-06T21:04:42ZIntroduction Understanding context and how this can be systematically assessed and incorporated is crucial to successful implementation. We describe how context has been assessed (including exploration or evaluation) in Global Alliance for Chron[...]![]()
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Daivadanam, Meena ; Ingram, Maia ; Sidney Annerstedt, Kristi ; Parker, Gary ; Bobrow, Kirsty ; Dolovich, Lisa ; Gould, Gillian ; Riddell, Michaela ; Vedanthan, Rajesh ; Webster, Jacqui ; Absetz, Pilvikki ; Molsted Alvesson, Helle ; Androutsos, Odysseas ; Chavannes, Niels ; Cortez, Briana ; Devarasetty, Praveen ; Fottrell, Edward ; Gonzalez-Salazar, Francisco ; Goudge, Jane ; Herasme, Omarys ; Jennings, Hannah ; Kapoor, Deksha ; Kamano, Jemima ; Kasteleyn, Marise J. ; Kyriakos, Christina ; Manios, Yannis ; Mogulluru, Kishor ; Owolabi, Mayowa ; Lazo-Porras, Maria ; Silva, Wnurinham ; Thrift, Amanda ; Uvere, Ezinne ; Webster, Ruth ; van der Kleij, Rianne ; Van Olmen, Josefien ; Vardavas, Constantine ; Zhang, Puhong | Public Library of Science | 2019-07-04T17:01:21ZINTRODUCTION: Understanding context and how this can be systematically assessed and incorporated is crucial to successful implementation. We describe how context has been assessed (including exploration or evaluation) in Global Alliance for Chro[...]![]()
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Sartori, Pablo ; Granger, Léo ; Chiu Fan, Lee ; Horowitz, Jordan M. | Public Library of Science | 2014-12-11Biological sensory systems react to changes in their surroundings. They are characterized by fast response and slow adaptation to varying environmental cues. Insofar as sensory adaptive systems map environmental changes to changes of their inter[...]![]()
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Crabtree-Ramírez, B. ; Caro-Vega, Y. ; Shepherd, B.E. ; Grinsztejn, B. ; Wolff, M. ; Cortes, C.P. ; Padgett, D. ; Carriquiry, G. ; Fink, V. ; Jayathilake, K. ; Person, A.K. ; McGowan, C. ; Sierra-Madero, J. ; CCASAnet | Public Library of Science | 2019-04-24T18:23:56ZBackground: Since 2009, earlier initiation of highly active antiretroviral therapy (HAART) after an opportunistic infection (OI) has been recommended based on lower risks of death and AIDS-related progression found in clinical trials. Delay in H[...]![]()
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Mahanty, Siddhartha ; Orrego, Miguel A. ; Cangalaya, Carla ; Adrianzen, M. Paz ; Arroyo, Gianfranco ; Calcina, Juan ; Gonzalez, Armando E. ; Garcia, Hector H. ; Guerra-Giraldez, Cristina ; Nash, Theodore E. ; Cysticercosis Working Group in Peru | Public Library of Science | 2019-01-25T16:03:22ZBACKGROUND: Neurocysticercosis (NCC) is an infection of the brain with the larval cyst of the tapeworm, Taenia solium. Cysticidal treatment induces parasite killing resulting in a post inflammatory response and seizures, which generally requires[...]![]()
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Grandjean, Louis ; Gilman, Robert H. ; Martin, Laura ; Soto, Esther ; Castro, Beatriz ; Lopez, Sonia ; Coronel, Jorge ; Castillo, Edith ; Alarcon, Valentina ; Lopez, Virginia ; San Miguel, Angela ; Quispe, Neyda ; Asencios, Luis ; Dye, Christopher ; Moore, David A. J. | Public Library of Science | 2019-02-06T14:53:08ZBACKGROUND: The "fitness" of an infectious pathogen is defined as the ability of the pathogen to survive, reproduce, be transmitted, and cause disease. The fitness of multidrug-resistant tuberculosis (MDRTB) relative to drug-susceptible tuberc[...]