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Galea, Jerome T. ; Monsour, Emmi ; Nurena, Cesar R. ; Blas, Magaly M. ; Brown, Brandon | Public Library of Science | 2019-01-25T15:18:36ZPURPOSE: Human papillomavirus (HPV) is the most common sexually transmitted infection globally and is responsible for a variety of cancers in men and women. An effective HPV vaccine licensed for use in girls and boys has been indicated for-but i[...]![]()
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Rougeron, V. ; Elguero, E. ; Arnathau, C. ; Hidalgo, B.A. ; Durand, P. ; Houze, S. ; Berry, A. ; Zakeri, S. ; Haque, R. ; Alam, M.S. ; Nosten, F. ; Severini, C. ; Woldearegai, T.G. ; Mordmüller, B. ; Kremsner, P.G. ; González-Cerón, L. ; Fontecha, G. ; Gamboa, D. ; Musset, L. ; Legrand, E. ; Noya, O. ; Pumpaibool, T. ; Harnyuttanakorn, P. ; Lekweiry, K.M. ; Albsheer, M.M. ; Hamid, M.M.A. ; Boukary, A.O.M.S. ; Trape, J.-F. ; Renaud, F. ; Prugnolle, F. | Public Library of Science | 2020-12-14T16:10:08ZMore than 200 million malaria clinical cases are reported each year due to Plasmodium vivax, the most widespread Plasmodium species in the world. This species has been neglected and understudied for a long time, due to its lower mortality in com[...]![]()
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Pajuelo, Monica J. ; Eguiluz, María ; Dahlstrom, Eric ; Requena, David ; Guzman, Frank ; Ramírez, Manuel ; Sheen, Patricia ; Frace, Michael ; Sammons, Scott ; Cama, Vitaliano ; Anzick, Sarah ; Bruno, Dan ; Mahanty, Siddhartha ; Wilkins, Patricia ; Nash, Theodore ; Gonzalez, Armando ; Garcia, Hector H. ; Gilman, Robert H. ; Porcella, Steve ; Zimic, Mirko | Public Library of Science | 2019-02-06T14:53:08ZBACKGROUND: Infections with Taenia solium are the most common cause of adult acquired seizures worldwide, and are the leading cause of epilepsy in developing countries. A better understanding of the genetic diversity of T. solium will improve p[...]![]()
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Berry, Alexander S. F. ; Salazar-Sanchez, Renzo ; Castillo-Neyra, Ricardo ; Borrini-Mayori, Katty ; Chipana-Ramos, Claudia ; Vargas-Maquera, Melina ; Ancca-Juarez, Jenny ; Naquira-Velarde, Cesar ; Levy, Michael Z. ; Brisson, Dustin | Public Library of Science | 2019-12-06T21:04:41ZChanging environmental conditions, including those caused by human activities, reshape biological communities through both loss of native species and establishment of non-native species in the altered habitats. Dynamic interactions with the abio[...]![]()
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Florentini, E.A. ; Angulo, N. ; Gilman, R.H. ; Alcántara, R. ; Roncal, E. ; Antiparra, R. ; Toscano, E. ; Vallejos, K. ; Kirwan, D. ; Zimic, M. ; Sheen, P. | Public Library of Science | 2020-12-14T16:06:23ZPyrazinamide (PZA) susceptibility testing in Mycobacterium tuberculosis (Mtb) is a current area of development and PZA-resistant strains are increasingly prevalent. Previous studies have demonstrated that the detection of pyrazinoic acid (POA), [...]![]()
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Pons, Maria J. ; Gomes, Cláudia ; Aguilar, Ruth ; Barrios, Diana ; Aguilar-Luis, Miguel Angel ; Ruiz, Joaquim ; Dobaño, Carlota ; Del Valle-Mendoza, Juana ; Moncunill, Gemma | Public Library of Science | 2017-10-09T17:11:19ZAnalysis of immune responses in Bartonella bacilliformis carriers are needed to understand acquisition of immunity to Carrion’s disease and may allow identifying biomarkers associated with bacterial infection and disease phases. Serum samples fr[...]![]()
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Charles, M.K. ; Lindegren, M.L. ; Wester, C.W. ; Blevins, M. ; Sterling, T.R. ; Dung, N.T. ; Dusingize, J.C. ; Avit-Edi, D. ; Durier, N. ; Castelnuovo, B. ; Nakigozi, G. ; Cortes, C.P. ; Ballif, M. ; Fenner, L. ; Ajayi, S. ; Anastos, K. ; Bashi, J. ; Bishai, W. ; Boulle, A. ; Braitstein, P. ; Carriquiry, G. ; Carter, J.E. ; Cegielski, P. ; Chimbetete, C. ; Davies, M.-A. ; Diero, L. ; Duda, S. ; Egger, M. ; Eboua, T.F. ; Gasser, A. ; Geng, E. ; Gnokori, J.C. ; Hardwicke, L. ; Hoffmann, C. ; Huebner, R. ; Kancheya, N. ; Kiertiburanakul, S. ; Kim, P. ; Lameck, D. ; Leroy, V. ; Lewden, C. ; Mandalakas, A. ; Maskew, M. ; McKaig, R. ; Mofenson, L. ; Mpoudi-Etame, M. ; Okwara, B. ; Phiri, S. ; Prasitsuebsai, W. ; Petit, A. ; Prozesky, H. ; Reid, S.E. ; Renner, L. ; Reubenson, G. ; Sohn, A. ; Vo, Q. ; Walker, D. ; Wehbe, F. ; Wejse, C. ; Williams, C. ; Wood, R. ; Wools-Kaloustian, K. ; Yao, Z. ; Yunihastuti, E. ; Zhang, F.J. ; Zhao, H.X. ; Han, N. ; Merati, T.P. ; Wirawan, D.N. ; Yuliana, F. ; Ditangco, R. ; Uy, E. ; Bantique, R. ; Phanuphak, P. ; Ruxrungtham, K. ; Avihingsanon, A. ; Khongphattanayothin, M. ; Sungkanuparph, S. ; Sanmeema, N. ; Chaiwarith, R. ; Sirisanthana, T. ; Kotarathititum, W. ; Pham, T.T. ; Cuong, D.D. ; Ha, H.L. ; Nguyen, V.K. ; Bui, V.H. ; Nguyen, T.D. ; Sohn, A.H. ; Petersen, B. ; Cooper, D.A. ; Law, M.G. ; Jiamsakul, A. ; Boettiger, D.C. ; Wati, D.K. ; Atmikasari, L.P.P. ; Malino, I.Y. ; Nallusamy, R. ; Chan, K.C. ; Lumbiganon, P. ; Kosalaraksa, P. ; Tharnprisan, P. ; Udomphanit, T. ; Phongsamart, W. ; Wittawatmongkol, O. ; Dung, K.T.K. ; Lam, N.V. ; An, P.N. ; Loan, N.T. ; Truong, H.K. ; Du, T.Q. ; Chau, N.H. ; Do, C.V. ; Ha, M.T. ; Nipathakosol, P. ; Kariminia, A. ; Mutimura, E. ; Gitembagara, A. ; Tatwangire, J. ; Izabelle, I. ; Niyongabo, T. ; Twizere, C. ; Baramperanye, E. ; Edmonds, A. ; Yotebieng, M. ; Azinyue, I. ; Ayangma, L. ; Dickinson, D. ; Eley, B. ; Fritz, C. ; Garone, D. ; Giddy, J. ; MacPhail, P. ; Moultrie, H. ; Ndirangu, J. ; Pestilli, S. ; Rabie, H. ; Stringer, J. ; Technau, K. ; Graber, C. ; Kaeser, F. ; Keiser, O. ; Cornell, M. ; Maxwell, N. ; Zannou, D.M. ; Ahouada, C. ; Akakpo, J. ; Ahomadegbé, C. ; Gougounon-Houéto, A. ; Azon-Kouanou, A. ; Houngbé, F. ; Sehonou, J. ; Koumakpaï, S. ; Alihonou, F. ; D'Almeida, M. ; Hodonou, I. ; Hounhoui, G. ; Sagbo, G. ; Tossa-Bagnan, L. ; Adjide, H. ; Drabo, J. ; Bognounou, R. ; Dienderé, A. ; Traore, E. ; Zoungrana, L. ; Zerbo, B. ; Sawadogo, A.B. ; Zoungrana, J. ; Héma, A. ; Soré, I. ; Bado, G. ; Tapsoba, A. ; Yé, D. ; Kouéta, F. ; Ouedraogo, S. ; Ouédraogo, R. ; Hiembo, W. ; Gansonré, M. ; Messou, E. ; Gnokoro, J.C. ; Koné, M. ; Kouakou, G.M. ; Bosse, C.A. ; Brou, K. ; Assi, A.I. ; Chenal, H. ; Hawerlander, D. ; Soppi, F. ; Minga, A. ; Abo, Y. ; Yoboue, J.-M. ; Eholié, S.P. ; Amego, M.D.N. ; Andavi, V. ; Diallo, Z. ; Ello, F. ; Tanon, A.K. ; Koule, S.O. ; Anzan, K.C. ; Guehi, C. ; Aka, E.A. ; Issouf, K.L. ; Kouakou, J.-C. ; N'Gbeche, M.-S. ; Pety, T. ; Kouakou, K. ; Moh, M. ; Yao, V.A. ; Folquet, M.A. ; Dainguy, M.-E. ; Kouakou, C. ; Méa-Assande, V.T. ; Oka-Berete, G. ; Zobo, N. ; Acquah, P. ; Kokora, M.-B. ; Timité-Konan, M. ; Ahoussou, L.D. ; Assouan, J.K. ; Sami, M.F. ; Kouadio, C. ; Goka, B. ; Welbeck, J. ; Sackey, A. ; Owiafe, S.N. ; Da Silva, Z.J. ; Paulo, J. ; Rodrigues, A. ; Da Silva, D. ; Medina, C. ; Oliviera-Souto, I. ; Østergaard, L. ; Laursen, A. ; Sodemann, M. ; Aaby, P. ; Fomsgaard, A. ; Erikstrup, C. ; Eugen-Olsen, J. ; Maïga, M.Y. ; Diakité, F.F. ; Kalle, A. ; Katile, D. ; Traore, H.A. ; Minta, D. ; Cissé, T. ; Dembelé, M. ; Doumbia, M. ; Fomba, M. ; Kaya, A.S. ; Traoré, A.M. ; Traoré, H. ; Toure, A.A. ; Dicko, F. ; Sylla, M. ; Berthé, A. ; Traoré, H.C. ; Koïta, A. ; Koné, N. ; N'Diaye, C. ; Coulibaly, S.T. ; Traoré, M. ; Traoré, N. ; Charurat, M. ; Alim, G. ; Dapiap, S. ; Otu ; Igbinoba, F. ; Benson, O. ; Adebamowo, C. ; James, J. ; Obaseki ; Osakede, P. ; Olasode, J. ; Seydi, M. ; Sow, P.S. ; Diop, B. ; Manga, N.M. ; Tine, J.M. ; Bassabi, C.C. ; Sy, H.S. ; Ba, A. ; Diagne, A. ; Dior, H. ; Faye, M. ; Gueye, R.D. ; Mbaye, A.D. ; Patassi, A. ; Kotosso, A. ; Kariyare, B.G. ; Gbadamassi, G. ; Komi, A. ; Mensah-Zukong, K.E. ; Pakpame, P. ; Lawson-Evi, A.K. ; Atakouma, Y. ; Takassi, E. ; Djeha, A. ; Ephoévigah, A. ; Djibril, S.E.-H. ; Dabis, F. ; Bissagnene, E. ; Arrivé, E. ; Coffie, P. ; Ekouevi, D. ; Jaquet, A. ; Sasco, A.J. ; Amani, D. ; Azani, J.-C. ; Balestre, E. ; Bessekon, S. ; Bohossou, F. ; Gilbert, C. ; Karcher, S. ; Gonsan, J.M. ; Le Carrou, J. ; Lenaud, S. ; Nchot, C. ; Malateste, K. ; Yao, A.R. ; Siloué, B. ; Clouet, G. ; Dosso, M. ; Doring, A. ; Kouakou, A. ; Rabourdin, E. ; Rivenc, J. ; Anglaret, X. ; Ba, B. ; Essanin, J.B. ; Ciaranello, A. ; Datté, S. ; Desmonde, S. ; Diby, J.-S.E. ; Gottlieb, G.S. ; Horo, A.G. ; Kangah, S.N. ; Malvy, D. ; Meless, D. ; Mounkaila-Harouna, A. ; Ndondoki, C. ; Shiboski, C. ; Tchounga, B. ; Thiébaut, R. ; Wandeler, G. ; McGowan, C. ; Cahn, P. ; Gotuzzo, Eduardo ; Reyes, M.W. ; Grinsztejn, B. ; Pape, J.W. ; Padgett, D. ; Madero, J.S. | Public Library of Science | 2019-04-24T18:23:55ZSetting: World Health Organization advocates for integration of HIV-tuberculosis (TB) services and recommends intensive case finding (ICF), isoniazid preventive therapy (IPT), and infection control ("Three I's") for TB prevention and control amo[...]![]()
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De Cerqueira, C.C.S. ; Hünemeier, T. ; Gomez-Valdés, J. ; Ramallo, V. ; Volasko-Krause, C.D. ; Barbosa, A.A.L. ; Vargas-Pinilla, P. ; Dornelles, R.C. ; Longo, D. ; Rothhammer, F. ; Bedoya, G. ; Canizales-Quinteros, S. ; Acuña-Alonzo, V. ; Gallo, C. ; Poletti, G. ; González-José, R. ; Salzano, F.M. ; Callegari-Jacques, S.M. ; Schuler-Faccini, L. ; Ruiz-Linares, A. ; Bortolini, M.C. | Public Library of Science | 2020-06-10T18:12:17ZThe understanding of the complex genotype-phenotype architecture of human pigmentation has clear implications for the evolutionary history of humans, as well as for medical and forensic practices. Although dozens of genes have previously been as[...]![]()
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Cerqueira, Caio Cesar Silva de ; Hunemeier, Tabita ; Gomez-Valdes, Jorge ; Ramallo, Virginia ; Volasko-Krause, Carla Daiana ; Barbosa, Ana Angelica Leal ; Vargas-Pinilla, Pedro ; Dornelles, Rodrigo Ciconet ; Longo, Danae ; Rothhammer, Francisco ; Bedoya, Gabriel ; Canizales-Quinteros, Samuel ; Acuna-Alonzo, Victor ; Gallo, Carla ; Poletti, Giovanni ; González-José, Rolando ; Salzano, Francisco Mauro ; Callegari-Jacques, Sidia Maria ; Schuler-Faccini, Lavinia ; Ruiz-Linares, Andrés ; Catira Bortolini, Maria | Public Library of Science | 2020-06-10T18:12:17ZThe understanding of the complex genotype-phenotype architecture of human pigmentation has clear implications for the evolutionary history of humans, as well as for medical and forensic practices. Although dozens of genes have previously been as[...]![]()
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Asensio, Irene ; Vicente Rubiano, Marina ; Muñoz Reoyo, María Jesús ; Fernández Carrión, Eduardo ; Sánchez-Vizcaíno, José Manuel ; Carballo, Matilde | Public Library of Science | 2016We analyzed six apiaries in several natural environments with a Mediterranean ecosystem in Madrid, central Spain, in order to understand how landscape and management characteristics may influence apiary health and bee production in the long term[...]![]()
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Mayta, H. ; Romero, Y.K. ; Pando, A. ; Verastegui, M. ; Tinajeros, F. ; Bozo, R. ; Henderson-Frost, J. ; Colanzi, R. ; Flores, J. ; Lerner, R. ; Bern, C. ; Gilman, R.H. ; Chagas Working Group in Peru and Bolivia | Public Library of Science | 2019-12-06T21:04:40ZBackground: The detection of Trypanosoma cruzi genetic material in clinical samples is considered an important diagnostic tool for Chagas disease. We have previously demonstrated that PCR using clot samples yields greater sensitivity than either[...]![]()
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Mayta, Holger ; Romero, Yomara K. ; Pando, Alejandra ; Verastegui, Manuela ; Tinajeros, Freddy ; Bozo, Ricardo ; Henderson-Frost, Josephine ; Colanzi, Rony ; Flores, Jorge ; Lerner, Richard ; Bern, Caryn ; Gilman, Robert H. | Public Library of Science | 2019-07-04T17:00:16ZBACKGROUND: The detection of Trypanosoma cruzi genetic material in clinical samples is considered an important diagnostic tool for Chagas disease. We have previously demonstrated that PCR using clot samples yields greater sensitivity than either[...]![]()
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Olliaro, Piero ; Fouque, Florence ; Kroeger, Axel ; Bowman, Leigh ; Velayudhan, Raman ; Santelli, Ana Carolina ; García, Diego ; Skewes Ramm, Ronald ; Sulaiman, Lokman H. ; Sanchez Tejeda, Gustavo ; Correa Morales, Fabián ; Gozzer, Ernesto ; Basso Garrido, César ; Chan Quang, Luong ; Gutierrez, Gamaliel ; Yadon, Zaida E. ; Runge-Ranzinger, Silvia | Public Library of Science | 2018-12-03T17:02:50ZBACKGROUND: Research has been conducted on interventions to control dengue transmission and respond to outbreaks. A summary of the available evidence will help inform disease control policy decisions and research directions, both for dengue and,[...]![]()
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Datta, Sumona ; Saunders, Matthew J. ; Tovar, Marco A. ; Evans, Carlton A. | Public Library of Science | 2019-01-25T16:59:39ZIn a Perspective accompanying Sylvia and colleagues, Carlton Evans and colleagues discuss the challenge of squaring policies around tuberculosis diagnosis with the realities of clinical practice in small villages and low-resource settings.![]()
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Chamakh-Ayari, Rym ; Bras-Gonçalves, Rachel ; Bahi-Jaber, Narges ; Petitdidier, Elodie ; Markikou-Ouni, Wafa ; Aoun, Karim ; Moreno, Javier ; Carrillo, Eugenia ; Salotra, Poonam ; Kaushal, Himanshu ; Negi, Narender Singh ; Arevalo, Jorge ; Falconi-Agapito, Francesca ; Privat, Angela ; Cruz, Maria ; Pagniez, Julie ; Papierok, Gerard-Marie ; Rhouma, Faten Bel Haj ; Torres, Pilar ; Lemesre, Jean-Loup ; Chenik, Mehdi ; Meddeb-Garnaoui, Amel | Public Library of Science | 2020-06-10T18:12:17ZPSA (Promastigote Surface Antigen) belongs to a family of membrane-bound and secreted proteins present in several Leishmania (L.) species. PSA is recognized by human Th1 cells and provides a high degree of protection in vaccinated mice. We evalu[...]![]()
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Palma, Sandra ; Chile, Nancy ; Carmen-Orozco, Rogger P. ; Trompeter, Grace ; Fishbeck, Kayla ; Cooper, Virginia ; Rapoport, Laura ; Bernal-Teran, Edson G. ; Condori, Beth J. ; Gilman, Robert H. ; Verastegui, Manuela R. | Public Library of Science | 2019-07-04T17:00:16ZTaenia solium is known to cause human cysticercosis while T. saginata does not. Comparative in vitro and in vivo studies on the oncosphere and the postoncospheral (PO) forms of T. solium and T. saginata may help to elucidate why cysticercosis ca[...]![]()
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Chile, Nancy ; Clark, Taryn ; Arana, Yanina ; Ortega, Ynes R. ; Palma, Sandra ; Mejia, Alan ; Angulo, Noelia ; Kosek, Jon C. ; Kosek, Margaret ; Gomez-Puerta, Luis A. ; Garcia, Hector H. ; Gavidia, Cesar M. ; Gilman, Robert H. ; Verastegui, Manuela | Public Library of Science | 2019-02-06T14:45:12ZBACKGROUND: The transitional period between the oncosphere and the cysticercus of Taenia solium is the postoncospheral (PO) form, which has not yet been completely characterized. The aim of this work was to standardize a method to obtain T. soli[...]![]()
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Coral-Almeida, Marco ; Rodriguez-Hidalgo, Richar ; Celi-Erazo, Maritza ; Garcia, Hector Hugo ; Rodriguez, Silvia ; Devleesschauwer, Brecht ; Benitez-Ortiz, Washington ; Dorny, Pierre ; Praet, Nicolas | Public Library of Science | 2020-06-10T18:12:16ZBACKGROUND: Human cysticercosis is a zoonotic disease causing severe health disorders and even death. While prevalence data become available worldwide, incidence rate and cumulative incidence figures are lacking, which limits the understanding o[...]![]()
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Cangalaya, Carla ; Zimic, Mirko ; Marzal, Miguel ; Gonzalez, Armando E. ; Guerra-Giraldez, Cristina ; Mahanty, Siddhartha ; Nash, Theodore E. ; Garcia, Hector H. | Public Library of Science | 2019-02-06T14:53:09ZBACKGROUND: Neurocysticercosis (NCC), infection of the central nervous system by Taenia solium cysticerci, is a pleomorphic disease. Inflammation around cysticerci is the major cause of disease but is variably present. One factor modulating the[...]![]()
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Gutfraind, Alexander ; Peterson, Jennifer K. ; Billig Rose, Erica ; Arevalo-Nieto, Claudia ; Sheen, Justin ; Condori-Luna, Gian Franco ; Tankasala, Narender ; Castillo-Neyra, Ricardo ; Condori-Pino, Carlos ; Anand, Priyanka ; Naquira-Velarde, Cesar ; Levy, Michael Z. | Public Library of Science | 2019-03-05T15:23:30ZBackground: Until recently, the Chagas disease vector, Triatoma infestans, was widespread in Arequipa, Perú, but as a result of a decades-long campaign in which over 70,000 houses were treated with insecticides, infestation prevalence is now gre[...]![]()
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Moreno, Marta ; Saavedra, Marlon P. ; Bickersmith, Sara A. ; Prussing, Catharine ; Michalski, Adrian ; Tong Rios, Carlos ; Vinetz, Joseph M. ; Conn, Jan E. | Public Library of Science | 2019-01-25T15:28:04ZAnopheles darlingi, the main malaria vector in the Neotropics, has been considered to be highly anthropophilic. However, many behavioral aspects of this species remain unknown, such as the range of blood-meal sources. Barrier screens were used t[...]![]()
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Bárez López, Soledad ; Grijota Martínez, Carmen ; Liao, Xiao-Hui ; Refetoff, Samuel ; Guadaño Ferraz, Ana | Public Library of Science | 2019-12-06Patients lacking the thyroid hormone (TH) transporter MCT8 present abnormal serum levels of TH: low thyroxine and high triiodothyronine. They also have severe neurodevelopmental defects resulting from cerebral hypothyroidism, most likely due to [...]![]()
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Boni, Raquel B. De ; Peratikos, Meridith B. ; Shepherd, Bryan E. ; Grinsztejn, Beatriz ; Cortes, Claudia ; Padgett, Denis ; Gotuzzo, Eduardo ; Belaunzaran-Zamudio, Pablo F. ; Rebeiro, Peter F. ; Duda, Stephany N. ; McGowan, Catherine C. | Public Library of Science | 2018-06-18T15:26:48ZBackground The HIV care cascade has improved in Latin America over the last decade. However, the influence of alcohol and noninjected drug use (NIDU) on cascade outcomes is mostly unknown. This study estimated the association of alcohol and NIDU[...]![]()
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García, Patricia J. ; Hernández-Córdova, Gustavo ; Pourjavaheri, Paria ; Gómez-Paredes, Hilbert J. ; Sudar, Samuel ; Bayer, Angela M. | Public Library of Science | 2018-11-30T17:17:14ZINTRODUCTION: Although the worldwide incidence of tuberculosis (TB) is slowly decreasing, annual infection rates in Peru remain among the highest in the Americas. Pharmacies could play an important role in facilitating early detection of TB. How[...]![]()
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Carrillo-Larco, Rodrigo M. ; Altez-Fernandez, Carlos ; Acevedo-Rodriguez, J. Gonzalo ; Ortiz-Acha, Karol ; Ugarte-Gil, Cesar | Public Library of Science | 2019-07-04T17:00:18ZBACKGROUND: Leptospirosis is a worldwide prevalent zoonosis and chronic kidney disease (CKD) is a leading global disease burden. Because of pathophysiological changes in the kidney, it has been suggested that these conditions may be associated. [...]![]()
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Serra-Casas, Elisa ; Manrique, Paulo ; Ding, Xavier C. ; Carrasco-Escobar, Gabriel ; Alava, Freddy ; Gave, Anthony ; Rodriguez, Hugo ; Contreras-Mancilla, Juan ; Rosas-Aguirre, Angel ; Speybroeck, Niko ; Gonzalez, Iveth J. ; Rosanas-Urgell, Anna ; Gamboa, Dionicia | Public Library of Science | 2019-01-25T15:28:05ZBACKGROUND: Loop-mediated isothermal DNA amplification (LAMP) methodology offers an opportunity for point-of-care (POC) molecular detection of asymptomatic malaria infections. However, there is still little evidence on the feasibility of impleme[...]![]()
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Clouse, K. ; Blevins, M. ; Lindegren, M.L. ; Yotebieng, M. ; Nguyen, D.T. ; Omondi, A. ; Michael, D. ; Zannou, D.M. ; Carriquiry, G. ; Pettit, A. ; IeDEA ; Gotuzzo, E. ; Mejia, F. ; Carriquiry, G. | Public Library of Science | 2019-04-24T18:23:56ZObjective: Xpert MTB/RIF is recommended by the World Health Organization (WHO) as the initial tuberculosis (TB) diagnostic test in individuals suspected of HIV-associated TB. We sought to evaluate field implementation of Xpert among a cohort of [...]![]()
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Jara, Marlene ; Berg, Maya ; Caljon, Guy ; de Muylder, Geraldine ; Cuypers, Bart ; Castillo, Denis ; Maes, Ilse ; Orozco, María Del Carmen ; Vanaerschot, Manu ; Dujardin, Jean-Claude ; Arevalo, Jorge | Public Library of Science | 2019-01-25T15:28:05ZIt was recently hypothesized that Leishmania amastigotes could constitute a semi-quiescent stage characterized by low replication and reduced metabolic activity. This concept developed with Leishmania (Leishmania) mexicana and Leishmania (Leishm[...]![]()
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Prussing, Catharine ; Saavedra, Marlon P. ; Bickersmith, Sara A. ; Alava, Freddy ; Guzman, Mitchel ; Manrique, Edgar ; Carrasco-Escobar, Gabriel ; Moreno, Marta ; Gamboa, Dionicia ; Vinetz, Joseph M. ; Conn, Jan E. | Public Library of Science | 2019-07-04T17:00:18ZIn Amazonian Peru, the primary malaria vector, Nyssorhynchus darlingi (formerly Anopheles darlingi), is difficult to target using standard vector control methods because it mainly feeds and rests outdoors. Larval source management could be a use[...]![]()
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Prussing, C. ; Saavedra, M.P. ; Bickersmith, S.A. ; Alava, F. ; Guzmán, M. ; Manrique, E. ; Carrasco-Escobar, G. ; Moreno, M. ; Gamboa, D. ; Vinetz, J.M. ; Conn, J.E. | Public Library of Science | 2019-12-06T20:57:51ZIn Amazonian Peru, the primary malaria vector, Nyssorhynchus darlingi (formerly Anopheles darlingi), is difficult to target using standard vector control methods because it mainly feeds and rests outdoors. Larval source management could be a use[...]![]()
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Alva, Alicia ; Cangalaya, Carla ; Quiliano, Miguel ; Krebs, Casey ; Gilman, Robert H. ; Sheen, Patricia ; Zimic, Mirko | Public Library of Science | 2019-01-25T15:28:05ZParasitic infections are generally diagnosed by professionals trained to recognize the morphological characteristics of the eggs in microscopic images of fecal smears. However, this laboratory diagnosis requires medical specialists which are lac[...]![]()
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Errea, Renato A. ; Vasquez-Rios, George ; Machicado, Jorge D. ; Gallardo, Maria Susana ; Cornejo, Marilhia ; Urquiaga, Jorge F. ; Montoya, Diego ; Zamudio, Rodrigo ; Terashima, Angélica ; Marcos, Luis A. ; Samalvides, Frine | Public Library of Science | 2019-02-06T14:53:09ZIn developing countries, education to health-care professionals is a cornerstone in the battle against neglected tropical diseases (NTD). Studies evaluating the level of knowledge of medical students in clinical and socio-demographic aspects o[...]![]()
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Valenciano, Alberto ; Baskin, Jon A. ; Abella, Juan ; Pérez-Ramos, Alejandro ; Ángeles Álvarez-Sierra, Ángeles ; Morales, Jorge ; Hartstone-Rose, Adam | Public Library of Science | 2016-04We describe cranial and mandibular remains of three undescribed individuals of the giant mustelid Megalictis ferox Matthew, 1907 from the latest Arikareean (Ar4), Early Miocene mammal fauna of Nebraska, and Wyoming (USA) housed at the American M[...]![]()
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Benziger, Catherine P. ; Bernabé-Ortiz, Antonio ; Gilman, Robert H. ; Checkley, William ; Smeeth, Liam ; Malaga, German ; Miranda, J. Jaime | Public Library of Science | 2019-02-06T14:53:10ZOBJECTIVE: We aimed to characterize metabolic status by body mass index (BMI) status. METHODS: The CRONICAS longitudinal study was performed in an age-and-sex stratified random sample of participants aged 35 years or older in four Peruvian set[...]![]()
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Guevara, Govinda ; Olortegui Flores, Yamileth ; Fernández de las Heras, Laura ; Perera González, Julián ; Navarro LLorens, Juana María | Public Library of Science | 2019-07-26Rhodococcus ruber Chol-4 is a potent steroid degrader that has a great potential as a biotechnological tool. As proof of concept, this work presents testosterone production from 4- androstene-3,17-dione by tailoring innate catabolic enzymes of t[...]![]()
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Faggion, C. M. ; Apaza, K. ; Ariza-Fritas, T. ; Malaga, L. ; Giannakopoulos, N. N. ; Alarcon, M. A. | Public Library of Science | 2019-01-25T16:36:29ZBackground Consensus guidelines are useful to improve clinical decision making. Therefore, the methodological evaluation of these guidelines is of paramount importance. Low quality information may guide to inadequate or harmful clinical decision[...]![]()
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Oriol-Tordera, B. ; Berdasco, M. ; Llano, A. ; Mothe, B. ; Gálvez, C. ; Martinez-Picado, J. ; Carrillo, J. ; Blanco, J. ; Duran-Castells, C. ; Ganoza, C. ; Sánchez, J. ; Clotet, B. ; Calle, M.L. ; Sánchez-Pla, A. ; Esteller, M. ; Brander, C. ; Ruiz-Riol, M. | Public Library of Science | 2020-12-14T16:10:02ZGWAS, immune analyses and biomarker screenings have identified host factors associated with in vivo HIV-1 control. However, there is a gap in the knowledge about the mechanisms that regulate the expression of such host factors. Here, we aimed to[...]![]()
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Vasquez, Ana L. ; Errea, Renato A. ; Hoces, Daniel ; Echevarria, Juan ; González-Lagos, Elsa ; Gotuzzo, Eduardo | Public Library of Science | 2019-01-25T15:28:06ZINTRODUCTION: Based on the hypothesis that HIV programs struggle to deliver health services that harmonize necessities of treatment and prevention, we described the outcomes of routinely provided HIV testing to partners of people living with HIV[...]![]()
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Torres-Roman, J. Smith ; Cruz-Avila, Yuridia ; Suarez-Osorio, Karina ; Arce-Huamaní, Miguel Ángel ; Menez-Sanchez, Alejandra ; Aveiro-Róbalo, Telmo Raúl ; Mejia, Christian R. ; Ruiz, Eloy F. | Public Library of Science | 2018-11-30T17:17:16ZINTRODUCTION: Motivation in medical students is positively associated with learning strategies. However, the evidence of a direct relationship between motivation and performance is vague. The objective of this study is to determine if the motiva[...]![]()
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Rodríguez, L. ; Bustamante, B. ; Huaroto, L. ; Agurto, C. ; Illescas, R. ; Ramírez, R. ; Diaz, A. ; Hidalgo, J. | Public Library of Science | 2019-01-25T16:36:29ZBackground The incidence of candidemia is increasing in developing countries. Very little is known about the epidemiology of candidemia in Peru. The aim of this study is to describe the incidence, microbiology, clinical presentation and outcomes[...]![]()
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Zavaleta, Carol ; Berrang-Ford, Lea ; Ford, James ; Llanos-Cuentas, Alejandro ; Carcamo, Cesar ; Ross, Nancy A. ; Lancha, Guillermo ; Sherman, Mya ; Harper, Sherilee L. ; Edge, Victoria ; Lwasa, Shuaib ; Namanya, Didacus B. | Public Library of Science | 2018-11-08T19:39:21ZBackground Climate change is affecting food systems globally, with implications for food security, nutrition, and the health of human populations. There are limited data characterizing the current and future consequences of climate change on loc[...]![]()
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Cura, Carolina I. ; Duffy, Tomas ; Lucero, Raul H. ; Bisio, Margarita ; Peneau, Julie ; Jimenez-Coello, Matilde ; Calabuig, Eva ; Gimenez, Maria J. ; Valencia Ayala, Edward ; Kjos, Sonia A. ; Santalla, Jose ; Mahaney, Susan M. ; Cayo, Nelly M. ; Nagel, Claudia ; Barcan, Laura ; Malaga Machaca, Edith S. ; Acosta Viana, Karla Y. ; Brutus, Laurent ; Ocampo, Susana B. ; Aznar, Christine ; Cuba Cuba, Cesar A. ; Gurtler, Ricardo E. ; Ramsey, Janine M. ; Ribeiro, Isabela ; VandeBerg, John L. ; Yadon, Zaida E. ; Osuna, Antonio ; Schijman, Alejandro G. | Public Library of Science | 2019-02-06T14:53:10ZBACKGROUND: Trypanosoma cruzi has been classified into six Discrete Typing Units (DTUs), designated as TcI-TcVI. In order to effectively use this standardized nomenclature, a reproducible genotyping strategy is imperative. Several typing scheme[...]![]()
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Moyano, Luz M. ; Saito, Mayuko ; Montano, Silvia M. ; Gonzalvez, Guillermo ; Olaya, Sandra ; Ayvar, Viterbo ; Gonzalez, Isidro ; Larrauri, Luis ; Tsang, Victor C. W. ; Llanos, Fernando ; Rodriguez, Silvia ; Gonzalez, Armando E. ; Gilman, Robert H. ; Garcia, Hector H. | Public Library of Science | 2020-06-10T18:12:16ZBACKGROUND: The prevalence of epilepsy added to inadequate treatment results in chronic morbidity and considerable mortality in poor populations. Neurocysticercosis (NCC), a helminthic disease of the central nervous system, is a leading cause o[...]![]()
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Pesantes, M.A. ; Moyano, L.M. ; Sommerville, C. ; Cysticercosis Working Group in Peru COHESION Project | Public Library of Science | 2020-12-14T16:10:04ZBackground Neurocysticercosis (NCC) is a helminthic disease of the central nervous system, and it is one of the leading causes of seizures and symptomatic epilepsy in countries with tropical regions like Peru. Studies of people with epilepsy in [...]![]()
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Ong, Catherine W. M. ; Elkington, Paul T. ; Brilha, Sara ; Ugarte-Gil, Cesar ; Tome-Esteban, Maite T. ; Tezera, Liku B. ; Pabisiak, Przemyslaw J. ; Moores, Rachel C. ; Sathyamoorthy, Tarangini ; Patel, Vimal ; Gilman, Robert H. ; Porter, Joanna C. ; Friedland, Jon S. | Public Library of Science | 2019-02-06T14:53:12ZPulmonary cavities, the hallmark of tuberculosis (TB), are characterized by high mycobacterial load and perpetuate the spread of M. tuberculosis. The mechanism of matrix destruction resulting in cavitation is not well defined. Neutrophils are e[...]![]()
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Arriola, Carmen S. ; Gonzalez, Armando E. ; Gomez-Puerta, Luis A. ; Lopez-Urbina, Maria T. ; Garcia, Hector H. ; Gilman, Robert H. | Public Library of Science | 2020-06-10T18:12:17ZTaenia solium infection causes severe neurological disease in humans. Even though infection and exposure to swine cysticercosis is scattered throughout endemic villages, location of the tapeworm only explains some of the nearby infections and is[...]![]()
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Limaye, Neha P. ; Rivas-Nieto, Andrea C. ; Carcamo, Cesar P. ; Blas, Magaly M. | Public Library of Science | 2018-11-30T22:50:34ZBACKGROUND: In rural areas of the Loreto region within the Peruvian Amazon, maternal mortality rate is above the national average and the majority of women deliver at home without care from a trained health care provider. METHODS: To develop com[...]![]()
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Loret de Mola, Christian ; Quispe, Renato ; Valle, Giancarlo A. ; Poterico, Julio A. | Public Library of Science | 2020-06-10T18:12:17ZBACKGROUND: Rapid urbanization, increase in food availability, and changes in diet and lifestyle patterns have been changing nutritional profiles in developing nations. We aimed to describe nutritional changes in children under 5 years and women[...]![]()
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Flores-Flores, Oscar ; Bell, Ruth ; Reynolds, Rodney ; Bernabé-Ortiz, Antonio | Public Library of Science | 2019-03-05T15:23:30ZBACKGROUND: Disability rates increase with age. In 2012, Peruvian older adults (> /= 65 years) represented 9% of the population. Additionally, older population reported disabilities at about 5 times the rate of Peruvians between 36 and 64 years [...]![]()
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Datta, S. ; Alvarado, K. ; Gilman, R.H. ; Valencia, T. ; Aparicio, C. ; Ramos, E.S. ; Montoya, R. ; Evans, C.A. | Public Library of Science | 2019-12-06T21:04:41ZBackground Assessing Mycobacterium tuberculosis (TB) viability by fluorescein diacetate (FDA) microscopy can predict TB culture results, treatment response and infectiousness. However, diverse methods have been published. We aimed to optimise FD[...]