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Public Library of Science |
Documentos disponibles de esta editorial (243)
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Castano, A. G. ; de Nanclares, G. P. ; Madariaga, L. ; Aguirre, M. ; Madrid, A. ; Chocron, S. ; Nadal, I. ; Navarro, M. ; Lucas, E. ; Fijo, J. ; Espino, M. ; Espitaletta, Z. ; Nieto, V. G. ; de Frutos, D. B. ; Loza, R. ; Pintos, G. ; Castaño, L. ; Ariceta, G. ; RenalTube Group | Public Library of Science | 2019-01-25T16:36:29ZIntroduction Type III Bartter syndrome (BS) is an autosomal recessive renal tubule disorder caused by loss-of-function mutations in the CLCNKB gene, which encodes the chloride channel protein ClC-Kb. In this study, we carried out a complete clin[...]![]()
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Delgado-Ratto, Christopher ; Gamboa, Dionicia ; Soto-Calle, Veronica-E. ; Van-den-Eede, Peter ; Torres, Eliana ; Sanchez-Martinez, Luis ; Contreras-Mancilla, Juan ; Rosanas-Urgell, Anna ; Rodriguez-Ferrucci, Hugo ; Llanos-Cuentas, Alejandro ; Erhart, Annette ; Van-Geertruyden, Jean-Pierre ; D'Alessandro, Umberto | Public Library of Science | 2019-02-06T14:45:12ZBACKGROUND: Characterizing the parasite dynamics and population structure provides useful information to understand the dynamic of transmission and to better target control interventions. Despite considerable efforts for its control, vivax malar[...]![]()
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Sikora, Martin ; Carpenter, Meredith L. ; Moreno-Estrada, Andres ; Henn, Brenna M. ; Underhill, Peter A. ; Sanchez-Quinto, Federico ; Zara, Ilenia ; Pitzalis, Maristella ; Sidore, Carlo ; Busonero, Fabio ; Maschio, Andrea ; Angius, Andrea ; Jones, Chris ; Mendoza-Revilla, Javier ; Nekhrizov, Georgi ; Dimitrova, Diana ; Theodossiev, Nikola ; Harkins, Timothy T. ; Keller, Andreas ; Maixner, Frank ; Zink, Albert ; Abecasis, Goncalo ; Sanna, Serena ; Cucca, Francesco ; Bustamante, Carlos D. | Public Library of Science | 2020-06-10T18:12:16ZGenome sequencing of the 5,300-year-old mummy of the Tyrolean Iceman, found in 1991 on a glacier near the border of Italy and Austria, has yielded new insights into his origin and relationship to modern European populations. A key finding of th[...]![]()
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Khatchikian, Camilo E. ; Foley, Erica A. ; Barbu, Corentin M. ; Hwang, Josephine ; Ancca-Juarez, Jenny ; Borrini-Mayori, Katty ; Quispe-Machaca, Victor R. ; Náquira, César ; Brisson, Dustin ; Levy, Michael Z. | Public Library of Science | 2019-02-06T14:53:10ZChagas disease is a vector-borne disease endemic in Latin America. Triatoma infestans, a common vector of this disease, has recently expanded its range into rapidly developing cities of Latin America. We aim to identify the environmental featu[...]![]()
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Mahanty, Siddhartha ; Orrego, Miguel Angel ; Mayta, Holger ; Marzal, Miguel ; Cangalaya, Carla ; Paredes, Adriana ; Gonzales-Gustavson, Eloy ; Arroyo, Gianfranco ; Gonzalez, Armando E. ; Guerra-Giraldez, Cristina ; Garcia, Hector H. ; Nash, Theodore E. | Public Library of Science | 2019-02-06T14:53:10ZCysticidal treatment of neurocysticercosis, an infection of humans and pig brains with Taenia solium, results in an early inflammatory response directed to cysts causing seizures and focal neurological manifestations. Treatment-induced pericysti[...]![]()
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Marco López, Eva María ; Rapino, Cinzia ; Caprioli, Antonio ; Borsini, Franco ; Laviola, Giovanni ; Maccarrone, Mauro | Public Library of Science | 2015-09-11Anxiety disorders are among the most prevalent psychiatric diseases with high personal costs and a remarkable socio-economic burden. However, current treatment of anxiety is far from satisfactory. Novel pharmacological targets have emerged in th[...]![]()
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Paz-Soldan, Valerie A. ; Morrison, Amy C. ; Sopheab, Heng ; Schwarz, Julia ; Bauer, Karin M. ; Mckenney, Jennie L. ; Chhea, Chhorvann ; Saphonn, Vonthanak ; Khuon, Dyna ; Hontz, Robert D. ; Gorbach, Pamina M. | Public Library of Science | 2019-12-06T21:02:53ZIn 2012, the U.S. Defense Threat Reduction Agency Joint Science and Technology Office initiated a program to develop novel point-of-need diagnostic devices for surveillance of emerging infectious diseases including dengue, malaria, plague, and [...]![]()
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Supo-Escalante, R.R. ; Médico, A. ; Gushiken, E. ; Olivos-Ramírez, G.E. ; Quispe, Y. ; Torres, F. ; Zamudio, M. ; Antiparra, R. ; Mario Amzel, L. ; Gilman, R.H. ; Sheen, P. ; Zimic, M. | Public Library of Science | 2020-12-14T16:10:16ZBackground: Pyrazinamide is an important drug against the latent stage of tuberculosis and is used in both first- and second-line treatment regimens. Pyrazinamide-susceptibility test usually takes a week to have a diagnosis to guide initial ther[...]![]()
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Rovira-Vallbona, Eduard ; Contreras-Mancilla, Juan José ; Ramirez, Roberson ; Guzmán-Guzmán, Mitchel ; Carrasco-Escobar, Gabriel ; Llanos-Cuentas, Alejandro ; Vinetz, Joseph M. ; Gamboa, Dionicia ; Rosanas-Urgell, Anna | Public Library of Science | 2019-01-25T15:28:08ZMalaria transmission requires that Anopheles mosquitoes ingest Plasmodium gametocyte stages circulating in the human bloodstream. In the context of malaria elimination, understanding the epidemiology of gametocytes relative to all Plasmodium inf[...]![]()
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Alroy, K.A. ; Huang, C. ; Gilman, R.H. ; Quispe-Machaca, V.R. ; Marks, M.A. ; Ancca-Juarez, J. ; Hillyard, M. ; Verastegui, M. ; Sanchez, G. ; Cabrera, L. ; Vidal, E. ; Billig, E.M.W. ; Cama, V.A. ; Naquira, C. ; Bern, C. ; Levy, M.Z. ; Working Group on Chagas Disease in Peru | Public Library of Science | 2019-04-24T18:23:55ZVector-borne transmission of Trypanosoma cruzi is seen exclusively in the Americas where an estimated 8 million people are infected with the parasite. Significant research in southern Peru has been conducted to understand T. cruzi infection and [...]![]()
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Villegas, Leonela ; Otero, Larissa ; Sterling, Timothy-R. ; Huaman, Moises-A. ; Van-der-Stuyft, Patrick ; Gotuzzo, Eduardo ; Seas, Carlos | Public Library of Science | 2019-02-06T14:48:07ZBACKGROUND: Isoniazid and rifampicin are the two most efficacious first-line agents for tuberculosis (TB) treatment. We assessed the prevalence of isoniazid and rifampicin mono-resistance, associated risk factors, and the association of mono-res[...]![]()
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Patra, Kailash P. ; Saito, Mayuko ; Atluri, Vidya L. ; Rolan, Hortensia G. ; Young, Briana ; Kerrinnes, Tobias ; Smits, Henk ; Ricaldi, Jessica N. ; Gotuzzo, Eduardo ; Gilman, Robert H. ; Tsolis, Renee M. ; Vinetz, Joseph M. | Public Library of Science | 2020-06-10T18:12:16ZHuman brucellosis is most commonly diagnosed by serology based on agglutination of fixed Brucella abortus as antigen. Nucleic acid amplification techniques have not proven capable of reproducibly and sensitively demonstrating the presence of B[...]![]()
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Zamudio, Carlos ; Krapp, Fiorella ; Choi, Howard W. ; Shah, Lena ; Ciampi, Antonio ; Gotuzzo, Eduardo ; Heymann, Jody ; Seas, Carlos ; Brewer, Timothy F. | Public Library of Science | 2019-02-06T14:53:12ZBACKGROUND: Tuberculosis (TB) transmission may occur with exposure to an infectious contact often in the setting of household environments, but extra-domiciliary transmission also may happen. We evaluated if using buses and/or minibuses as publi[...]![]()
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Suarez, Milagros ; Valencia, B. M. ; Jara, Marlene ; Alba, Milena ; Boggild, Andrea K. ; Dujardin, Jean-Claude ; Llanos-Cuentas, Alejandro ; Arevalo, Jorge ; Adaui, Vanessa | Public Library of Science | 2019-02-06T14:53:09ZBACKGROUND: Cutaneous leishmaniasis (CL) is a skin disease caused by the protozoan parasite Leishmania. Few studies have assessed the influence of the sample collection site within the ulcer and the sampling method on the sensitivity of parasito[...]![]()
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Cangalaya, Carla ; Bustos, Javier A. ; Calcina, Juan ; Vargas-Calla, Ana ; Mamani, Javier ; Suarez, Diego ; Arroyo, Gianfranco ; Gonzalez, Armando E. ; Chacaltana, Juan ; Guerra-Giraldez, Cristina ; Mahanty, Siddhartha ; Nash, Theodore E. ; Garcia, Hector H. | Public Library of Science | 2019-01-25T16:03:19ZBACKGROUND: The onset of anthelmintic treatment of neurocysticercosis (NCC) provokes an acute immune response of the host, which in human cases is associated with exacerbation of neurological symptoms. This inflammation can occur at the first da[...]