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Moreno, Marta ; Saavedra, Marlon P. ; Bickersmith, Sara A. ; Prussing, Catharine ; Michalski, Adrian ; Tong Rios, Carlos ; Vinetz, Joseph M. ; Conn, Jan E. | Public Library of Science | 2019-01-25T15:28:04ZAnopheles darlingi, the main malaria vector in the Neotropics, has been considered to be highly anthropophilic. However, many behavioral aspects of this species remain unknown, such as the range of blood-meal sources. Barrier screens were used t[...]texto impreso
Bárez López, Soledad ; Grijota Martínez, Carmen ; Liao, Xiao-Hui ; Refetoff, Samuel ; Guadaño Ferraz, Ana | Public Library of Science | 2019-12-06Patients lacking the thyroid hormone (TH) transporter MCT8 present abnormal serum levels of TH: low thyroxine and high triiodothyronine. They also have severe neurodevelopmental defects resulting from cerebral hypothyroidism, most likely due to [...]texto impreso
Boni, Raquel B. De ; Peratikos, Meridith B. ; Shepherd, Bryan E. ; Grinsztejn, Beatriz ; Cortes, Claudia ; Padgett, Denis ; Gotuzzo, Eduardo ; Belaunzaran-Zamudio, Pablo F. ; Rebeiro, Peter F. ; Duda, Stephany N. ; McGowan, Catherine C. | Public Library of Science | 2018-06-18T15:26:48ZBackground The HIV care cascade has improved in Latin America over the last decade. However, the influence of alcohol and noninjected drug use (NIDU) on cascade outcomes is mostly unknown. This study estimated the association of alcohol and NIDU[...]texto impreso
García, Patricia J. ; Hernández-Córdova, Gustavo ; Pourjavaheri, Paria ; Gómez-Paredes, Hilbert J. ; Sudar, Samuel ; Bayer, Angela M. | Public Library of Science | 2018-11-30T17:17:14ZINTRODUCTION: Although the worldwide incidence of tuberculosis (TB) is slowly decreasing, annual infection rates in Peru remain among the highest in the Americas. Pharmacies could play an important role in facilitating early detection of TB. How[...]texto impreso
Carrillo-Larco, Rodrigo M. ; Altez-Fernandez, Carlos ; Acevedo-Rodriguez, J. Gonzalo ; Ortiz-Acha, Karol ; Ugarte-Gil, Cesar | Public Library of Science | 2019-07-04T17:00:18ZBACKGROUND: Leptospirosis is a worldwide prevalent zoonosis and chronic kidney disease (CKD) is a leading global disease burden. Because of pathophysiological changes in the kidney, it has been suggested that these conditions may be associated. [...]texto impreso
Serra-Casas, Elisa ; Manrique, Paulo ; Ding, Xavier C. ; Carrasco-Escobar, Gabriel ; Alava, Freddy ; Gave, Anthony ; Rodriguez, Hugo ; Contreras-Mancilla, Juan ; Rosas-Aguirre, Angel ; Speybroeck, Niko ; Gonzalez, Iveth J. ; Rosanas-Urgell, Anna ; Gamboa, Dionicia | Public Library of Science | 2019-01-25T15:28:05ZBACKGROUND: Loop-mediated isothermal DNA amplification (LAMP) methodology offers an opportunity for point-of-care (POC) molecular detection of asymptomatic malaria infections. However, there is still little evidence on the feasibility of impleme[...]texto impreso
Clouse, K. ; Blevins, M. ; Lindegren, M.L. ; Yotebieng, M. ; Nguyen, D.T. ; Omondi, A. ; Michael, D. ; Zannou, D.M. ; Carriquiry, G. ; Pettit, A. ; IeDEA ; Gotuzzo, E. ; Mejia, F. ; Carriquiry, G. | Public Library of Science | 2019-04-24T18:23:56ZObjective: Xpert MTB/RIF is recommended by the World Health Organization (WHO) as the initial tuberculosis (TB) diagnostic test in individuals suspected of HIV-associated TB. We sought to evaluate field implementation of Xpert among a cohort of [...]texto impreso
Jara, Marlene ; Berg, Maya ; Caljon, Guy ; de Muylder, Geraldine ; Cuypers, Bart ; Castillo, Denis ; Maes, Ilse ; Orozco, María Del Carmen ; Vanaerschot, Manu ; Dujardin, Jean-Claude ; Arevalo, Jorge | Public Library of Science | 2019-01-25T15:28:05ZIt was recently hypothesized that Leishmania amastigotes could constitute a semi-quiescent stage characterized by low replication and reduced metabolic activity. This concept developed with Leishmania (Leishmania) mexicana and Leishmania (Leishm[...]texto impreso
Prussing, Catharine ; Saavedra, Marlon P. ; Bickersmith, Sara A. ; Alava, Freddy ; Guzman, Mitchel ; Manrique, Edgar ; Carrasco-Escobar, Gabriel ; Moreno, Marta ; Gamboa, Dionicia ; Vinetz, Joseph M. ; Conn, Jan E. | Public Library of Science | 2019-07-04T17:00:18ZIn Amazonian Peru, the primary malaria vector, Nyssorhynchus darlingi (formerly Anopheles darlingi), is difficult to target using standard vector control methods because it mainly feeds and rests outdoors. Larval source management could be a use[...]texto impreso
Prussing, C. ; Saavedra, M.P. ; Bickersmith, S.A. ; Alava, F. ; Guzmán, M. ; Manrique, E. ; Carrasco-Escobar, G. ; Moreno, M. ; Gamboa, D. ; Vinetz, J.M. ; Conn, J.E. | Public Library of Science | 2019-12-06T20:57:51ZIn Amazonian Peru, the primary malaria vector, Nyssorhynchus darlingi (formerly Anopheles darlingi), is difficult to target using standard vector control methods because it mainly feeds and rests outdoors. Larval source management could be a use[...]texto impreso
Alva, Alicia ; Cangalaya, Carla ; Quiliano, Miguel ; Krebs, Casey ; Gilman, Robert H. ; Sheen, Patricia ; Zimic, Mirko | Public Library of Science | 2019-01-25T15:28:05ZParasitic infections are generally diagnosed by professionals trained to recognize the morphological characteristics of the eggs in microscopic images of fecal smears. However, this laboratory diagnosis requires medical specialists which are lac[...]texto impreso
Errea, Renato A. ; Vasquez-Rios, George ; Machicado, Jorge D. ; Gallardo, Maria Susana ; Cornejo, Marilhia ; Urquiaga, Jorge F. ; Montoya, Diego ; Zamudio, Rodrigo ; Terashima, Angélica ; Marcos, Luis A. ; Samalvides, Frine | Public Library of Science | 2019-02-06T14:53:09ZIn developing countries, education to health-care professionals is a cornerstone in the battle against neglected tropical diseases (NTD). Studies evaluating the level of knowledge of medical students in clinical and socio-demographic aspects o[...]texto impreso
Valenciano, Alberto ; Baskin, Jon A. ; Abella, Juan ; Pérez-Ramos, Alejandro ; Ángeles Álvarez-Sierra, Ángeles ; Morales, Jorge ; Hartstone-Rose, Adam | Public Library of Science | 2016-04We describe cranial and mandibular remains of three undescribed individuals of the giant mustelid Megalictis ferox Matthew, 1907 from the latest Arikareean (Ar4), Early Miocene mammal fauna of Nebraska, and Wyoming (USA) housed at the American M[...]texto impreso
Benziger, Catherine P. ; Bernabé-Ortiz, Antonio ; Gilman, Robert H. ; Checkley, William ; Smeeth, Liam ; Malaga, German ; Miranda, J. Jaime | Public Library of Science | 2019-02-06T14:53:10ZOBJECTIVE: We aimed to characterize metabolic status by body mass index (BMI) status. METHODS: The CRONICAS longitudinal study was performed in an age-and-sex stratified random sample of participants aged 35 years or older in four Peruvian set[...]texto impreso
Guevara, Govinda ; Olortegui Flores, Yamileth ; Fernández de las Heras, Laura ; Perera González, Julián ; Navarro LLorens, Juana María | Public Library of Science | 2019-07-26Rhodococcus ruber Chol-4 is a potent steroid degrader that has a great potential as a biotechnological tool. As proof of concept, this work presents testosterone production from 4- androstene-3,17-dione by tailoring innate catabolic enzymes of t[...]