|
Título:
|
High Prevalence of Asymptomatic Neurocysticercosis in an Endemic Rural Community in Peru
|
|
Autores:
|
Moyano, Luz M. ;
O'Neal, Seth E. ;
Ayvar, Viterbo ;
Gonzalvez, Guillermo ;
Gamboa, Ricardo ;
Vilchez, Percy ;
Rodriguez, Silvia ;
Reistetter, Joe ;
Tsang, Victor C. W. ;
Gilman, Robert H. ;
Gonzalez, Armando E. ;
Garcia, Hector H.
|
|
Tipo de documento:
|
texto impreso
|
|
Editorial:
|
Public Library of Science, 2019-02-06T14:45:56Z
|
|
Nota general:
|
info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
|
|
Idiomas:
|
Inglés
|
|
Palabras clave:
|
Editados por otras instituciones
,
Artículos
,
Artículos en revistas indizadas
|
|
Resumen:
|
BACKGROUND: Neurocysticercosis is a common helminthic infection of the central nervous system and an important cause of adult-onset epilepsy in endemic countries. However, few studies have examined associations between neurologic symptoms, serology and radiographic findings on a community-level. METHODOLOGY: We conducted a population-based study of resident's >/=2 years old in a highly endemic village in Peru (pop. 454). We applied a 14 -question neurologic screening tool and evaluated serum for antibodies against Taenia solium cysticercosis using enzyme-linked immunoelectrotransfer blot (LLGP-EITB). We invited all residents >/=18 years old to have non-contrast computerized tomography (CT) of the head. PRINCIPAL FINDINGS: Of the 385 residents who provided serum samples, 142 (36.9%) were seropositive. Of the 256 residents who underwent CT scan, 48 (18.8%) had brain calcifications consistent with NCC; 8/48 (17.0%) reported a history of headache and/or seizures. Exposure to T. solium is very common in this endemic community where 1 out of 5 residents had brain calcifications. However, the vast majority of people with calcifications were asymptomatic. CONCLUSION: This study reports a high prevalence of NCC infection in an endemic community in Peru and confirms that a large proportion of apparently asymptomatic residents have brain calcifications that could provoke seizures in the future.
|
|
En línea:
|
http://doi.org/10.1371/journal.pntd.0005130
|
