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Tremblay, Joshua C. ; Hoiland, Ryan L. ; Howe, Connor A. ; Coombs, Geoff B. ; Vizcardo-Galindo, Gustavo A. ; Figueroa-Mujica, Romulo J. ; Bermudez, Daniela ; Gibbons, Travis D. ; Stacey, Benjamin S. ; Bailey, Damian M. ; Tymko, Michael M. ; MacLeod, David B. ; Gasho, Chris ; Villafuerte, Francisco C. ; Pyke, Kyra E. ; Ainslie, Philip N. | American Heart Association | 2019-12-06T20:57:40ZExcessive erythrocytosis (EE; hemoglobin concentration [Hb] > /=21 g/dL in adult males) is associated with increased cardiovascular risk in highlander Andeans. We sought to quantify shear stress and assess endothelial function via flow-mediated [...]texto impreso
Tremblay, Joshua C. ; Coombs, Geoff B. ; Howe, Connor A. ; Vizcardo-Galindo, Gustavo A. ; Figueroa-Mujica, Romulo J. ; Bermudez, Daniela ; Tymko, Michael M. ; Villafuerte, Francisco C. ; Ainslie, Philip N. ; Pyke, Kyra E. | American Physiological Society | 2019-12-06T21:04:46ZExcessive erythrocytosis [EE; hemoglobin concentration (Hb) > /= 21 g/dL in adult men] is a maladaptive high-altitude pathology associated with increased cardiovascular risk and reduced reactive hyperemia flow-mediated dilation (FMD); however,[...]texto impreso
Busch, Stephen A. ; van Diepen, Sean ; Steele, Andrew R. ; Meah, Victoria L. ; Simpson, Lydia L. ; Figueroa-Mujica, Romulo J. ; Vizcardo-Galindo, Gustavo ; Villafuerte, Francisco C. ; Tymko, Michael M. ; Ainslie, Philip N. ; Moore, Jonathan P. ; Stembridge, Mike ; Steinback, Craig D. | Frontiers Media | 2020-07-14T00:00:59ZBackground: Ascent to altitude increases the prevalence of arrhythmogenesis in low-altitude dwelling populations (Lowlanders). High altitude populations (i.e., Nepalese Sherpa) may have arrhythmias resistant adaptations that prevent arrhythmogen[...]texto impreso
Stembridge, Mike ; Williams, Alexandra M. ; Gasho, Christopher ; Dawkins, Tony G. ; Drane, Aimee ; Villafuerte, Francisco C. ; Levine, Benjamin D. ; Shave, Rob ; Ainslie, Philip N. | National Academy of Sciences | 2019-08-08T15:23:47ZIn contrast to Andean natives, high-altitude Tibetans present with a lower hemoglobin concentration that correlates with reproductive success and exercise capacity. Decades of physiological and genomic research have assumed that the lower hemogl[...]texto impreso
Stembridge, Mike ; Williams, Alexandra M. ; Gasho, Christopher ; Dawkins, Tony G. ; Drane, Aimee ; Villafuerte, Francisco C. ; Levine, Benjamin D. ; Shave, Rob ; Ainslie, Philip N. | National Academy of Sciences | 2019-12-06T20:57:47ZIn contrast to Andean natives, high-altitude Tibetans present with a lower hemoglobin concentration that correlates with reproductive success and exercise capacity. Decades of physiological and genomic research have assumed that the lower hemogl[...]
