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Título:
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Minimally Invasive Saliva Testing to Monitor Norovirus Infection in Community Settings
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Autores:
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Pisanic, Nora ;
Ballard, Sarah-Blythe ;
Colquechagua, Fabiola D. ;
Francois, Ruthly ;
Exum, Natalie ;
Yori, Pablo Penataro ;
Schwab, Kellogg J. ;
Granger, Douglas A. ;
Detrick, Barbara ;
Olortegui, Maribel Paredes ;
Mayta, Holger ;
Sánchez, Gerardo J. ;
Gilman, Robert H. ;
Heaney, Christopher D. ;
Vinjé, Jan ;
Kosek, Margaret N.
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Tipo de documento:
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texto impreso
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Editorial:
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Oxford University Press, 2019-03-05T15:23:28Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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Background: Norovirus is a leading cause of acute gastroenteritis worldwide. Routine norovirus diagnosis requires stool collection. The goal of this study was to develop and validate a noninvasive method to diagnose norovirus to complement stool diagnostics and to facilitate studies on transmission. Methods: A multiplex immunoassay to measure salivary immunoglobulin G (IgG) responses to 5 common norovirus genotypes (GI.1, GII.2, GII.4, GII.6, and GII.17) was developed. The assay was validated using acute and convalescent saliva samples collected from Peruvian children
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En línea:
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http://doi.org/10.1093/infdis/jiy638
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