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Autor Llanos-Cuentas, Alejandro |
Documentos disponibles escritos por este autor (38)
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Delgado-Ratto, Christopher ; Gamboa, Dionicia ; Soto-Calle, Veronica-E. ; Van-den-Eede, Peter ; Torres, Eliana ; Sanchez-Martinez, Luis ; Contreras-Mancilla, Juan ; Rosanas-Urgell, Anna ; Rodriguez-Ferrucci, Hugo ; Llanos-Cuentas, Alejandro ; Erhart, Annette ; Van-Geertruyden, Jean-Pierre ; D'Alessandro, Umberto | Public Library of Science | 2019-02-06T14:45:12ZBACKGROUND: Characterizing the parasite dynamics and population structure provides useful information to understand the dynamic of transmission and to better target control interventions. Despite considerable efforts for its control, vivax malar[...]texto impreso
Rovira-Vallbona, Eduard ; Contreras-Mancilla, Juan José ; Ramirez, Roberson ; Guzmán-Guzmán, Mitchel ; Carrasco-Escobar, Gabriel ; Llanos-Cuentas, Alejandro ; Vinetz, Joseph M. ; Gamboa, Dionicia ; Rosanas-Urgell, Anna | Public Library of Science | 2019-01-25T15:28:08ZMalaria transmission requires that Anopheles mosquitoes ingest Plasmodium gametocyte stages circulating in the human bloodstream. In the context of malaria elimination, understanding the epidemiology of gametocytes relative to all Plasmodium inf[...]texto impreso
Suarez, Milagros ; Valencia, B. M. ; Jara, Marlene ; Alba, Milena ; Boggild, Andrea K. ; Dujardin, Jean-Claude ; Llanos-Cuentas, Alejandro ; Arevalo, Jorge ; Adaui, Vanessa | Public Library of Science | 2019-02-06T14:53:09ZBACKGROUND: Cutaneous leishmaniasis (CL) is a skin disease caused by the protozoan parasite Leishmania. Few studies have assessed the influence of the sample collection site within the ulcer and the sampling method on the sensitivity of parasito[...]texto impreso
Jara, Marlene ; Valencia, B. M. ; Adaui, Vanessa ; Alba, Milena ; Lau, Rachel ; Arevalo, Jorge ; Llanos-Cuentas, Alejandro ; Boggild, Andrea K. | American Society of Tropical Medicine and Hygiene | 2019-02-06T14:57:38ZMucosal leishmaniasis (ML) is a disfiguring manifestation of Leishmania (Viannia) infection. We evaluated parasite load (PL) over time as a potential biomarker of treatment outcome in ML. PL was assessed with kinetoplast DNA quantitative real-t[...]texto impreso
Barros, Nicolas ; Vasquez, Nestor ; Woll, Fernando ; Sanchez, Cesar ; Valencia, B. M. ; Llanos-Cuentas, Alejandro ; White, A. Clinton ; Montes, Martin | American Society of Tropical Medicine and Hygiene | 2018-12-01T00:04:15ZTo evaluate the dynamics of regulatory T cells (Tregs) during tegumentary leishmaniasis, we assessed peripheral blood and biopsies from 54 patients. Patients with cutaneous leishmaniasis (CL) had a decreased proportion of Tregs in the peripheral[...]texto impreso
Lacerda, Marcus V. G. ; Llanos-Cuentas, Alejandro ; Krudsood, Srivicha ; Lon, Chanthap ; Saunders, David L. ; Mohammed, Rezika ; Yilma, Daniel ; Batista Pereira, Dhelio ; Espino, Fe E. J. ; Mia, Reginaldo Z. ; Chuquiyauri, Raúl ; Val, Fernando ; Casapía, Martin ; Monteiro, Wuelton M. ; Brito, Marcelo A. M. ; Costa, Monica R. F. ; Buathong, Nillawan ; Noedl, Harald ; Diro, Ermias ; Getie, Sisay ; Wubie, Kalehiwot M. ; Abdissa, Alemseged ; Zeynudin, Ahmed ; Abebe, Cherinet ; Tada, Mauro S. ; Brand, Francoise ; Beck, Hans-Peter ; Angus, Brian ; Duparc, Stephan ; Kleim, Jorg-Peter ; Kellam, Lynda M. ; Rousell, Victoria M. ; Jones, Sion W. ; Hardaker, Elizabeth ; Mohamed, Khadeeja ; Clover, Donna D. ; Fletcher, Kim ; Breton, John J. ; Ugwuegbulam, Cletus O. ; Green, Justin A. ; Koh, Gavin C. K. W. | Massachusetts Medical Society | 2019-07-04T17:00:24ZBACKGROUND: Treatment of Plasmodium vivax malaria requires the clearing of asexual parasites, but relapse can be prevented only if dormant hypnozoites are cleared from the liver (a treatment termed "radical cure"). Tafenoquine is a single-dose 8[...]texto impreso
Soto-Calle, Veronica ; Rosas-Aguirre, Angel ; Llanos-Cuentas, Alejandro ; Abatih, Emmanuel ; DeDeken, Redgi ; Rodriguez, Hugo ; Rosanas-Urgell, Anna ; Gamboa, Dionicia ; D Alessandro, Umberto ; Erhart, Annette ; Speybroeck, Niko | Nature Research | 2019-01-25T16:03:21ZMalaria remains a major public health problem in the Peruvian Amazon where the persistence of high-risk transmission areas (hotspots) challenges the current malaria control strategies. This study aimed at identifying significant space-time clust[...]texto impreso
Llanos-Cuentas, Alejandro ; Lacerda, Marcus V. ; Rueangweerayut, Ronnatrai ; Krudsood, Srivicha ; Gupta, Sandeep K. ; Kochar, Sanjay K. ; Arthur, Preetam ; Chuenchom, Nuttagarn ; Möhrle, Jörg J. ; Duparc, Stephan ; Ugwuegbulam, Cletus ; Kleim, Jorg-Peter ; Carter, Nick ; Green, Justin A. ; Kellam, Lynda | Elsevier | 2020-06-10T18:12:14ZBACKGROUND: Clinical effectiveness of previous regimens to treat Plasmodium vivax infection have been hampered by compliance. We aimed to assess the dose-response, safety, and tolerability of single-dose tafenoquine plus 3-day chloroquine for P [...]texto impreso
St-Jean, Pamela-L. ; Xue, Zhengyu ; Carter, Nick ; Koh, Gavin-C. K. W. ; Duparc, Stephan ; Taylor, Maxine ; Beaumont, Claire ; Llanos-Cuentas, Alejandro ; Rueangweerayut, Ronnatrai ; Krudsood, Srivicha ; Green, Justin-A. ; Rubio, Justin-P. | BMC | 2019-02-06T14:48:06ZBACKGROUND: Tafenoquine (TQ) and primaquine (PQ) are 8-aminoquinolines (8-AQ) with anti-hypnozoite activity against vivax malaria. PQ is the only FDA-approved medicine for preventing relapsing Plasmodium vivax infection and TQ is currently in [...]texto impreso
Llanos-Cuentas, Alejandro ; Lacerda, Marcus V. G. ; Hien, Tran T. ; Velez, Ivan D. ; Namaik-Larp, Chayadol ; Chu, Cindy S. ; Villegas, Maria F. ; Val, Fernando ; Monteiro, Wuelton M. ; Brito, Marcelo A. M. ; Costa, Monica R. F. ; Chuquiyauri, Raúl ; Casapía, Martin ; Nguyen, Chau H. ; Aruachan, Sandra ; Papwijitsil, Ratchadaporn ; Nosten, Francois H. ; Bancone, Germana ; Angus, Brian ; Duparc, Stephan ; Craig, Graham ; Rousell, Victoria M. ; Jones, Sion W. ; Hardaker, Elizabeth ; Clover, Donna D. ; Kendall, Lindsay ; Mohamed, Khadeeja ; Koh, Gavin C. K. W. ; Wilches, Viviana M. ; Breton, John J. ; Green, Justin A. | Massachusetts Medical Society | 2019-07-04T17:01:20ZBACKGROUND: Tafenoquine, a single-dose therapy for Plasmodium vivax malaria, has been associated with relapse prevention through the clearance of P. vivax parasitemia and hypnozoites, termed "radical cure." METHODS: We performed a phase 3, pros[...]texto impreso
Carrasco-Escobar, Gabriel ; Castro, Marcia C. ; Barboza, José Luis ; Ruiz-Cabrejos, Jorge ; Llanos-Cuentas, Alejandro ; Vinetz, Joseph M. ; Gamboa, Dionicia | PeerJ | 2019-07-04T17:01:24ZInfectious disease dynamics are affected by human mobility more powerfully than previously thought, and thus reliable traceability data are essential. In rural riverine settings, lack of infrastructure and dense tree coverage deter the implement[...]texto impreso
Kariyawasam, Ruwandi ; Mukkala, Avinash N. ; Lau, Rachel ; Valencia, Braulio M. ; Llanos-Cuentas, Alejandro ; Boggild, Andrea K. | BMC | 2019-07-04T17:01:24ZBackground: Leishmania RNA virus-1 (LRV1) is a double-stranded RNA virus identified in 20-25% of Viannia-species endemic to Latin America, and is believed to accelerate cutaneous to mucosal leishmaniasis over time. Our objective was to quantify[...]texto impreso
Sherman, Mya ; Ford, James ; Llanos-Cuentas, Alejandro ; Valdivia, Maria Jose ; Bussalleu Rivera, Alejandro ; Indigenous Health Adaptation to Climate Change Research Group | Springer Verlag | 2019-02-22T14:55:28ZRainfall variability and related hydrological disasters are serious threats to agricultural production in developing countries. Since projections of climate change indicate an increase in the frequency and intensity of climatic hazards such as f[...]