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López Rodríguez, Ana Belén ; Acaz Fonseca, Estefanía ; Viveros, María Paz ; García Segura, Luis Miguel | Public Library of Sciences (PLOS) | 2015-06-03Traumatic brain injury (TBI) incidence rises during adolescence because during this critical neurodevelopmental period some risky behaviors increase. The purpose of this study was to assess the contribution of cannabinoid receptors (CB1 and CB2)[...]texto impreso
Díez Hernando, Sergio ; Mejías, Andrés ; Sánchez, Diego ; Gutiérrez Pozo, Gabriel ; Ganfornina, María D. | Public Library of Sciences (PLOS) | 2020-06-19The Lipocalin Apolipoprotein D (ApoD) is one of the few genes consistently overexpressed in the aging brain, and in most neurodegenerative and psychiatric diseases. Its functions include metabolism regulation, myelin management, neuroprotection,[...]texto impreso
Visser, Marcel E. ; Gienapp, Phillip ; Husby, Arild ; Morrisey, Michael ; Hera Fernández, Iván de la ; Pulido Delgado, Francisco ; Both, Christiaan | Public Library of Sciences (PLOS) | 2015-04Climate change has differentially affected the timing of seasonal events for interacting trophic levels, and this has often led to increased selection on seasonal timing. Yet, the environmental variables driving this selection have rarely been i[...]texto impreso
Arriero Higueras, Elena ; Wanelik, Klara M. ; Birtles, Richard J. ; Bradley, Janette E. ; Jackson, Joseph A. ; Paterson, Steve ; Begon, Mike | Public Library of Sciences (PLOS) | 2017-08Inbred mouse strains, living in simple laboratory environments far removed from nature, have been shown to vary consistently in their immune response. However, wildlife populations are typically outbreeding and face a multiplicity of challenges,[...]texto impreso
Sánchez Bretaño, Aída ; Blanco Imperiali, Ayelén M. ; Unniappan, Suraj ; Kah, Olivier ; Gueguen, Marie-M. ; Bertucci, Juan I. ; Alonso Gómez, Ángel Luis ; Valenciano González, Ana Isabel ; Isorna Alonso, Esther ; Delgado, María J. | Public Library of Sciences (PLOS) | 2015-10-27Ghrelin is a gut-brain peptide hormone, which binds to the growth hormone secretagogue receptor (GHS-R) to regulate a wide variety of biological processes in fish. Despite these prominent physiological roles, no studies have reported the anatomi[...]texto impreso
Mela Rivas, Virginia ; Díaz, Francisca ; Borcel, Erika ; Argente, Jesús ; Chowen, Julie A. ; Viveros, María Paz | Public Library of Sciences (PLOS) | 2015-09-18Maternal deprivation (MD) during neonatal life has diverse long-term behavioral effects and alters the development of the hippocampus and frontal cortex, with several of these effects being sexually dimorphic. MD animals show a marked reduction [...]texto impreso
Demuro, Martina ; Arnold, Lee J. ; Parés, Josep M. ; Pérez González, Alfredo ; Ortega Martínez, Ana Isabel ; Arsuaga, Juan Luis ; Bermúdez de Castro, José María ; Carbonell i Roura, Eudald | Public Library of Sciences (PLOS) | 2014-10-22The archaeological karstic infill site of Galería Complex, located within the Atapuerca system (Spain), has produced a large faunal and archaeological record (Homo sp. aff. heidelbergensis fossils and Mode II lithic artefacts) belonging to the M[...]texto impreso
Maddock, Simon T. ; Briscoe, Andrew G. ; Wilkinson, Mark ; Waeschenbach, Andrea ; San Mauro, Diego ; Day, Julia J. ; Littlewood, D. Tim J. ; Foster, Peter G. ; Nussbaum, Ronald A. ; Gower, David J. | Public Library of Sciences (PLOS) | 2016-06Mitochondrial genome (mitogenome) sequences are being generated with increasing speed due to the advances of next-generation sequencing (NGS) technology and associated analytical tools. However, detailed comparisons to explore the utility of alt[...]texto impreso
Munk, Estefanía de ; Palomo, Valle ; Muñoz Sáez, Emma ; Pérez, Daniel I. ; Gómez Miguel, Begoña ; Solas Alados, Mª Teresa ; Gil, Carmen ; Martínez, Ana ; Arahuetes Portero, Rosa María | Public Library of Sciences (PLOS) | 2016-09-15Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron degenerative disease that has no effective treatment up to date. Drug discovery tasks have been hampered due to the lack of knowledge in its molecular etiology together with the l[...]texto impreso
Arriero Higueras, Elena ; Müller, Inge ; Juvaste, Risto ; Martínez, Francisco Javier ; Bertolero, Albert | Public Library of Sciences (PLOS) | 2015-02-13The ability to control infections is a key trait for migrants that must be balanced against other costly features of the migratory life. In this study we explored the links between migration and disease ecology by examining natural variation in [...]texto impreso
Martín Forés, Irene ; Guerin, Greg R. ; Lowe, Andrew J. | Public Library of Sciences (PLOS) | 2017-06-01Weeds are commonly considered a threat to biodiversity, yet interactions between native and exotic species in grasslands are poorly understood and reported results vary depending on the spatial scale of study, the factors controlled for and the [...]