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Título:
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Sustained Domestic Vector Exposure Is Associated With Increased Chagas Cardiomyopathy Risk but Decreased Parasitemia and Congenital Transmission Risk Among Young Women in Bolivia
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Autores:
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Kaplinski, Michelle ;
Jois, Malasa ;
Galdos-Cardenas, Gerson ;
Rendell, Victoria R. ;
Shah, Vishal ;
Do, Rose Q. ;
Marcus, Rachel ;
Pena, Melissa S. Burroughs ;
Abastoflor, Maria Del Carmen ;
LaFuente, Carlos ;
Bozo, Ricardo ;
Valencia, Edward ;
Verastegui, Manuela ;
Colanzi, Rony ;
Gilman, Robert H. ;
Bern, Caryn
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Tipo de documento:
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texto impreso
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Editorial:
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Oxford University Press, 2019-02-06T14:52:17Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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BACKGROUND: We studied women and their infants to evaluate risk factors for congenital transmission and cardiomyopathy in Trypanosoma cruzi-infected women. METHODS: Women provided data and blood for serology and quantitative polymerase chain reaction (PCR). Infants of infected women had blood tested at 0 and 1 month by microscopy, PCR and immunoblot, and serology at 6 and 9 months. Women underwent electrocardiography (ECG). RESULTS: Of 1696 women, 456 (26.9%) were infected; 31 (6.8%) transmitted T. cruzi to their infants. Women who transmitted had higher parasite loads than those who did not (median, 62.0 [interquartile range {IQR}, 25.8-204.8] vs 0.05 [IQR, 0-29.6]; P
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En línea:
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http://doi.org/10.1093/cid/civ446
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