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Título:
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Is restless legs syndrome associated with chronic mountain sickness?
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Autores:
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Vizcarra-Escobar, Darwin ;
Mendiola-Yamasato, Andrea ;
Risco-Rocca, Jorge ;
Marinos-Velarde, Alejandro ;
Juarez-Belaunde, Alan ;
Anculle-Arauco, Victor ;
Rivera-Chira, Maria
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Tipo de documento:
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texto impreso
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Editorial:
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Elsevier, 2019-02-06T14:53:41Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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BACKGROUND: Restless legs syndrome (RLS) and chronic mountain sickness (CMS) share physiological traits. Our objective was to explore a possible association between RLS and CMS. METHODS: We carried a cross-sectional study with male subjects living between 4100 and 4300 m above sea level. Participants underwent a clinical interview, physical examination, electrocardiographic (EKG) recording, and spirometry. We classified subjects into CMS, Limbo, and healthy high-altitude dwellers (hHAD), according to their Quinghai score and hematocrit levels. We applied the "Paradigm of questions for epidemiological studies of RLS," The International Restless Leg Syndrome Study Group Scale, and the Pittsburgh Sleep Quality Index. Logistic regression analysis was used to determine the association between variables. RESULTS: Seventy-eight male subjects were included. Forty subjects were hHAD, 23 were CMS patients, and 15 participants were considered as Limbo. CMS and Limbo subjects had a higher frequency of RLS (p /=6 (p = 0.026) were independently associated with RLS diagnosis. CONCLUSIONS: Our results did not show a direct association between RLS and CMS; however, RLS was associated with reduced oxygen saturation. Hence, RLS could represent an early clinical manifestation of hypoxia, or, in CMS natural history, an early sign of maladaptation to high altitude.
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En línea:
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http://doi.org/10.1016/j.sleep.2015.03.013
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