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Arroyo, Gianfranco ; Bustos, Javier A. ; Lescano, Andres G. ; Gonzales, Isidro ; Saavedra, Herbert ; Rodriguez, Silvia ; Pretell, E. Javier ; Bonato, Pierina S. ; Lanchote, Vera L. ; Takayanagui, Osvaldo M. ; Horton, John ; Gonzalez, Armando E. ; Gilman, Robert H. ; Garcia, Hector H. | Oxford University Press | 2019-07-04T16:59:18ZBackground: Albendazole is the drug of choice for the treatment of parenchymal neurocysticercosis, although its efficacy is suboptimal. Plasma levels of albendazole sulfoxide (ASOX), the active metabolite of albendazole, are highly variable amon[...]texto impreso
Arroyo, Gianfranco ; Bustos, Javier A. ; Lescano, Andres G. ; Gonzales, Isidro ; Saavedra, Herbert ; Rodriguez, Silvia ; Pretell, E. Javier ; Bonato, Pierina S. ; Lanchote, Vera L. ; Takayanagui, Osvaldo M. ; Horton, John ; Gonzalez, Armando E. ; Gilman, Robert H. ; Garcia, Hector H. | Oxford University Press | 2019-12-06T21:02:55ZBACKGROUND: The efficacy of albendazole therapy in patients with parenchymal neurocysticercosis (NCC) is suboptimal. Plasma levels of albendazole sulfoxide (ASOX), the active metabolite of albendazole, are highly variable among patients. We hypo[...]texto impreso
Arroyo, Gianfranco ; Rodriguez, Silvia ; Lescano, Andres G. ; Alroy, Karen A. ; Bustos, Javier A. ; Santivañez, Saul ; Gonzales, Isidro ; Saavedra, Herbert ; Pretell, E. Javier ; Gonzalez, Armando E. ; Gilman, Robert H. ; Tsang, Victor C. W. ; Garcia, Hector H. ; Cysticercosis Working Group in Peru | Oxford University Press | 2018-11-30T02:09:29ZBackground: The enzyme-linked immunoelectrotransfer blot (EITB) assay is the reference serological test for neurocysticercosis (NCC). A positive result on EITB does not always correlate with the presence of active infections in the central nervo[...]texto impreso
Miranda, J. Jaime ; Bernabé-Ortiz, Antonio ; Diez-Canseco, Francisco ; Malaga, German ; Cárdenas, María K. ; Carrillo-Larco, Rodrigo M. ; Pesantes, M. Amalia ; Araya, Ricardo ; Boggio, Oscar ; Checkley, William ; García, Patricia J. ; Leon-Velarde, Fabiola ; Lescano, Andres G. ; Montori, Victor ; Pan, William ; Rivera-Chira, Maria ; Sacksteder, Katherine ; Smeeth, Liam ; Garcia, Hector H. ; Gilman, Robert H. | Elsevier | 2019-02-06T14:59:06ZThe CRONICAS Centre of Excellence in Chronic Diseases, based at Universidad Peruana Cayetano Heredia, was created in 2009 with support from the U.S. National Heart, Lung, and Blood Institute (NHLBI). The vision of CRONICAS is to build a globally[...]texto impreso
Rojas-Jaimes, Jesus ; Frischtak, Helena L. ; Arenas, Jose ; Lescano, Andres G. | American Society of Tropical Medicine and Hygiene | 2018-12-03T17:02:51ZMucosal leishmaniasis (ML) is associated with progressive tissue destruction and granuloma formation, often after a considerable period of latency from an initial cutaneous infection. We report a case of recurrent epistaxis of 3 years duration a[...]texto impreso
Ahmed, Ayman ; Daily, Johanna P. ; Lescano, Andres G. ; Golightly, Linnie M. ; Fasina, Abiola | American Society of Tropical Medicine and Hygiene | 2020-07-14T00:00:52ZThe brain drain of professionals from low- and middle-income countries (LMICs) to developed countries is well documented and partially due to the challenges faced by biomedical researchers to establish themselves back at home, after training abr[...]texto impreso
Lescano, Andres G. ; Pray, Ian W. ; Gonzalez, Armando E. ; Gilman, Robert H. ; Tsang, Victor C. W. ; Gamboa, Ricardo ; Guezala, M. Claudia ; Aybar, Viterbo ; Rodriguez, Silvia ; Moulton, Lawrence H. ; Leontsini, Elli ; Gonzalvez, Guillermo ; O'Neal, Seth E. ; Garcia, Hector H. ; Cysticercosis Working Group in Peru | American Society of Tropical Medicine and Hygiene | 2019-07-04T16:59:24ZThe pork tapeworm, Taenia solium, is among the leading causes of preventable epilepsy in the world and is common in rural areas of developing countries where sanitation is limited and pigs have access to human feces. Prior studies in rural vill[...]texto impreso
Comparative genomic analysis of Leishmania (Viannia) peruviana and Leishmania (Viannia) braziliensis
Valdivia, Hugo O. ; Reis-Cunha, Joao L. ; Rodrigues-Luiz, Gabriela F. ; Baptista, Rodrigo P. ; Baldeviano, G. Christian ; Gerbasi, Robert V. ; Dobson, Deborah E. ; Pratlong, Francine ; Bastien, Patrick ; Lescano, Andres G. ; Beverley, Stephen M. ; Bartholomeu, Daniella C. | BMC | 2019-02-06T14:52:14ZBACKGROUND: The Leishmania (Viannia) braziliensis complex is responsible for most cases of New World tegumentary leishmaniasis. This complex includes two closely related species but with different geographic distribution and disease phenotypes, [...]texto impreso
Garcia, Hector H. ; Lescano, Andres G. ; Gonzales, Isidro ; Bustos, Javier A. ; Pretell, E. Javier ; Horton, John ; Saavedra, Herbert ; Gonzalez, Armando E. ; Gilman, Robert H. | Oxford University Press | 2019-02-06T14:45:34ZBACKGROUND: The efficacy of current antiparasitic treatment for cerebral Taenia solium cysticercosis with either albendazole (ABZ) or praziquantel (PZQ) is suboptimal. A recent study demonstrated that combining these 2 antiparasitic drugs improv[...]texto impreso
Zorrilla, Victor ; De Los Santos, Maxy B. ; Espada, Liz ; Santos, Rocío Del Pilar ; Fernández, Roberto ; Urquia, Albino ; Stoops, Craig A. ; Ballard, Sarah-Blythe ; Lescano, Andres G. ; Vásquez, Gissella M. ; Valdivia, Hugo O. | Public Library of Science | 2019-01-25T15:18:33ZBACKGROUND: Cutaneous leishmaniasis (CL) is an important health problem in the New World affecting civilian and military populations that are frequently exposed in endemic settings. The Peruvian region of Madre de Dios located near the border wi[...]texto impreso
Salmón-Mulanovich, Gabriela ; Blazes, David L. ; Lescano, Andres G. ; Bausch, Daniel G. ; Montgomery, Joel M. ; Pan, William K. | American Society of Tropical Medicine and Hygiene | 2019-02-06T14:57:38ZDengue virus (DENV) was reintroduced to Peru in the 1990s and has been reported in Puerto Maldonado (population ~65,000) in the Peruvian southern Amazon basin since 2000. This region also has the highest human migration rate in the country, main[...]texto impreso
Garcia, Hector H. ; Gonzales, Isidro ; Lescano, Andres G. ; Bustos, Javier A. ; Zimic, Mirko ; Escalante, Diego ; Saavedra, Herbert ; Gavidia, Martin ; Rodriguez, Lourdes ; Najar, Enrique ; Umeres, Hugo ; Pretell, E. Javier | Elsevier | 2020-06-10T18:12:14ZBACKGROUND: Neurocysticercosis causes a substantial burden of seizure disorders worldwide. Treatment with either praziquantel or albendazole has suboptimum efficacy. We aimed to establish whether combination of these drugs would increase cystici[...]texto impreso
Durand, Salomon ; Cabezas, César ; Lescano, Andres G. ; Galvez, Mariela ; Gutierrez, Sonia ; Arrospide, Nancy ; Álvarez, Carlos ; Santolalla, Meddly L. ; Bacon, David J. ; Graf, Paul C. F. | American Society of Tropical Medicine and Hygiene | 2020-06-10T18:11:30ZWe evaluated the efficacy of three primaquine (PQ) regimes to prevent relapses with Plasmodium vivax through an open-label randomized trial in Loreto, Peru. Vivax monoinfections were treated with chloroquine for 3 days and PQ in three different [...]texto impreso
Huicho, Luis ; Molina, Cristina ; Diez-Canseco, Francisco ; Lema, Claudia ; Miranda, J. Jaime ; Huayanay-Espinoza, Carlos A. ; Lescano, Andres G. | BMC | 2019-02-06T14:52:36ZBACKGROUND: Deployment of health workforce in rural areas is critical to reach universal health coverage. Students' perceptions towards practice in rural areas likely influence their later choice of a rural post. We aimed at exploring perceptio[...]texto impreso
Loyola, Steev ; Sanchez, Juan F. ; Maguiña, Edson ; Canal, Enrique ; Castillo, Rosa ; Bernal, Manuela ; Meza, Yocelinda ; Tilley, Drake H. ; Oswald, William E. ; Heitzinger, Kristen ; Lescano, Andres G. ; Rocha, Claudio A. | American Society of Tropical Medicine and Hygiene | 2020-07-14T00:02:32ZDrinking water contamination is a frequent problem in developing countries and could be associated with bacterial pathogen carriage in feces. We evaluated the association between the risk of drinking water and bacterial carrier status in childre[...]
