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Gonzalez, Armando E. ; Codd, Ellen E. ; Horton, John ; Garcia, Hector H. ; Gilman, Robert H. | Taylor & Francis | 2019-03-05T15:25:03ZINTRODUCTION: Oxfendazole (methyl [5-(phenylsulphinyl)-1H benzimidazole-2-yl] carbamate) has a particularly long metabolic half-life in ruminants, and its metabolite fenbendazole also has anthelminthic action. A very limited number of drugs are [...]texto impreso
An, Guohua ; Murry, Daryl J. ; Gajurel, Kiran ; Bach, Thanh ; Deye, Greg ; Stebounova, Larissa V. ; Codd, Ellen E. ; Horton, John ; Gonzalez, Armando E. ; Garcia, Hector H. ; Ince, Dilek ; Hodgson-Zingman, Denice ; Nomicos, Effie Y. H. ; Conrad, Thomas ; Kennedy, Jessie ; Jones, Walt ; Gilman, Robert H. ; Winokur, Patricia | American Society for Microbiology | 2019-07-04T17:00:20ZCysticercosis is a parasitic disease that frequently involves the human central nervous system (CNS), and current treatment options are limited. Oxfendazole, a veterinary medicine belonging to the benzimidazole family of anthelmintic drugs, has[...]texto impreso
Codd, Ellen E. ; Ng, Hanna H. ; McFarlane, Claire ; Riccio, Edward S. ; Doppalapudi, Rupa ; Mirsalis, Jon C. ; Horton, R. John ; Gonzalez, Armando E. ; Garcia, H. Hugo ; Gilman, Robert H. | Sage publications | 2019-02-06T14:52:38ZA 2-week study in rats identified target organs of oxfendazole toxicity to be bone marrow, epididymis, liver, spleen, testis, and thymus. Female rats had greater oxfendazole exposure and exhibited toxicities at lower doses than did males. Decrea[...]
