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Mejia Maza, A. ; Carmen-Orozco, R.P. ; Carter, E.S. ; Dávila-Villacorta, D.G. ; Castillo, G. ; Morales, J.D. ; Mamani, J. ; Gavidia, C.M. ; Alroy, J. ; Sterling, C.R. ; Gonzalez, A.E. ; Garcia, H.H. ; Woltjer, R.L. ; Verástegui, M.R. ; Gilman, R.H. ; for the Cysticercosis Working Group in Peru | Wiley | 2019-12-06T21:02:57ZNeurocysticercosis is a parasitic brain disease caused by the larval form (Cysticercus cellulosae) of Taenia solium and is the leading cause of preventable epilepsy worldwide. However, the pathophysiology and relation to the wide range of clinic[...]texto impreso
Lescano, A.G. ; Pray, I.W. ; Gonzalez, A.E. ; Gilman, R.H. ; Tsang, V.C.W. ; Gamboa, R. ; Guezala, M.C. ; Aybar, V. ; Rodriguez, S. ; Moulton, L.H. ; Leontsini, E. ; Gonzalvez, G. ; O'Neal, S.E. ; Garcia, H.H. | American Society of Tropical Medicine and Hygiene | 2019-12-06T20:57:48ZThe pork tapeworm, Taenia solium, is among the leading causes of preventable epilepsy in the world and is common in rural areas of developing countries where sanitation is limited and pigs have access to human feces. Prior studies in rural villa[...]texto impreso
Del Brutto, O.H. ; Arroyo, G. ; Gonzalez, A.E. ; Zambrano, M. ; Garcia, H.H. | Sociedad Ecuatoriana de Neurología, Liga Ecuatoriana Contra la Epilepsia | 2019-02-22T14:54:06ZObjetivo: Evaluar la prevalencia de cisticercosis porcina en la parroquia rural Atahualpa, un poblado donde se ha demostrado endemia de neurocisticercosis humana. Diseño: Para el presente estudio, se colectarán muestras de sangre de aproximadame[...]texto impreso
Gomez-Puerta, L. ; Vargas-Calla, A. ; Castillo, Y. ; Lopez-Urbina, M.T. ; Dorny, P. ; Garcia, H.H. ; Gonzalez, A.E. ; O'Neal, S.E. | BMC | 2019-12-06T21:02:58ZBackground: Taenia solium is an important zoonotic parasite that infects humans as definitive host (taeniasis) and pigs as intermediate host (cysticercosis). Serological diagnosis of porcine cysticercosis is limited to antigen detection using EL[...]texto impreso
Gomez-Puerta, L.A. ; Garcia, H.H. ; Gonzalez, A.E. ; Cysticercosis Working Group in Peru | Elsevier | 2019-04-25T15:46:34ZBeetles are intermediate hosts for human and animal parasites, and several beetle species have been shown to carry Taenia eggs. An experimental porcine cysticercosis infection model was developed using beetles (Ammophorus rubripes) infected with[...]texto impreso
Vargas-Calla, A. ; Gomez-Puerta, L.A. ; Lopez, M.T. ; Garcia, H.H. ; Gonzalez, A.E. ; for the Cysticercosis Working Group in Peru | Springer Verlag | 2019-12-06T21:02:55ZSeveral studies have been performed to determine specific antigens for the diagnosis of tapeworms. One of these antigens is Tso31, which is used to differentiate Taenia solium and Taenia saginata in human feces. The aim of the present work was t[...]texto impreso
Gomez-Puerta, L.A. ; Gonzalez, A.E. ; Gavidia, C. ; Ayvar, V. ; Garcia, H.H. ; Lopez-Urbina, M.T. | Elsevier | 2019-04-25T15:46:34ZThe efficacy of oxfendazole (OFZ) on Taenia hydatigena metacestodes, also called Cysticercus tenuicollis ( C. tenuicollis), was studied in 648 raising pigs. This study was performed in Tumbes Department in Peru, an endemic area for cysticercosis[...]texto impreso
Gonzalez, A.E. ; Codd, E.E. ; Horton, J. ; Garcia, H.H. ; Gilman, R.H. | Taylor & Francis | 2019-12-06T21:02:58ZIntroduction: Oxfendazole (methyl [5-(phenylsulphinyl)-1H benzimidazole-2-yl] carbamate) has a particularly long metabolic half-life in ruminants, and its metabolite fenbendazole also has anthelminthic action. A very limited number of drugs are [...]texto impreso
Bustos, J.A. ; Ninaquispe, B.E. ; Rodriguez, S. ; Castillo, Y. ; Yang, S.Y. ; Gilman, R.H. ; Dorny, P. ; Gabriël, S. ; Garcia, H.H. ; Gonzalez, A.E. | American Society of Tropical Medicine and Hygiene | 2019-12-06T21:02:58ZThe pig is the natural intermediate host of Taenia solium, a parasite causing significant burden of disease in both humans and pigs. Porcine cysticercosis is traditionally detected via tongue palpation and slaughterhouse meat inspection, both wi[...]texto impreso
Bach, T. ; Galbiati, S. ; Kennedy, J.K. ; Deye, G. ; Nomicos, E.Y.H. ; Codd, E.E. ; Garcia, H.H. ; Horton, J. ; Gilman, R.H. ; Gonzalez, A.E. ; Winokur, P. ; An, G. | American Society for Microbiology | 2020-12-14T16:06:05ZNeurocysticercosis and trichuriasis are difficult-to-treat parasitic infections that affect more than 1.5 billion people worldwide. Oxfendazole, a potent broad-spectrum benzimidazole anthelmintic approved for use in veterinary medicine, has show[...]texto impreso
An, G. ; Murry, D.J. ; Gajurel, K. ; Bach, T. ; Deye, G. ; Stebounova, L.V. ; Codd, E.E. ; Horton, J. ; Gonzalez, A.E. ; Garcia, H.H. ; Ince, D. ; Hodgson-Zingman, D. ; Nomicos, E.Y.H. ; Conrad, T. ; Kennedy, J. ; Jones, W. ; Gilman, R.H. ; Winokur, P. | American Society for Microbiology | 2019-12-06T20:57:46ZCysticercosis is a parasitic disease that frequently involves the human central nervous system (CNS), and current treatment options are limited. Oxfendazole, a veterinary medicine belonging to the benzimidazole family of anthelmintic drugs, has [...]texto impreso
Recombinant protein- and synthetic peptide-based immunoblot test for diagnosis of neurocysticercosis
Noh, J. ; Rodriguez, S. ; Lee, Y.-M. ; Handali, S. ; Gonzalez, A.E. ; Gilman, R.H. ; Tsang, V.C.W. ; Garcia, H.H. ; Wilkins, P.P. | American Society for Microbiology | 2020-06-10T18:12:15ZOne of the most well-characterized tests for diagnosing neurocysticercosis (NCC) is the enzyme-linked immunoelectrotransfer blot (EITB) assay developed at the CDC, which uses lentil lectin-bound glycoproteins (LLGP) extracted from Taenia solium [...]texto impreso
Gonzales, I. ; Miranda, J.J. ; Rodriguez, S. ; Vargas, V. ; Cjuno, A. ; Smeeth, L. ; Gonzalez, A.E. ; Tsang, V.C.W. ; Gilman, R.H. ; Garcia, H.H. | Wiley | 2019-02-22T14:54:30ZObjectives: To examine the prevalence of seizures, epilepsy and seropositivity to cysticercosis in rural villagers (cysticercosis-endemic setting), rural-to-urban migrants into a non-endemic urban shanty town and urban inhabitants of the same no[...]texto impreso
Pray, I.W. ; Wakeland, W. ; Pan, W. ; Lambert, W.E. ; Garcia, H.H. ; Gonzalez, A.E. ; O'Neal, S.E. | BioMed Central | 2020-12-14T16:10:05ZBackground: The pork tapeworm, Taenia solium, is a serious public health problem in rural low-resource areas of Latin America, Africa and Asia, where the associated conditions of nuerocysticercosis (NCC) and porcine cysticercosis cause substanti[...]texto impreso
Perez, L.A. ; Castillo, Y. ; Espinoza, C. ; Toribio, L.M. ; Santos, Y. ; Martel, K.S. ; Wilkins, P.P. ; Bustos, J.A. ; Garcia, H.H. ; Castro-Sesquen, Y.E. ; Gilman, R.H. ; Gonzalez, A.E. ; Tsang, V.C.W. ; Rodriguez, S. ; Gonzalez, I. ; Saavedra, H. ; Sanchez, S. ; Martinez, M. ; Verastegui, M. ; Zimic, M. ; Santivanez, S. ; Mayta, H. ; Pajuelo, M. ; Arroyo, G. ; Lopez, M.T. ; Gomez, L. ; Vargas, A. ; Gavidia, C.M. ; Moyano, L.M. ; Gamboa, R. ; Muro, C. ; Vichez, P. ; O´neal, S. ; Handali, S. ; Noh, J. ; Nash, T.E. ; Mahanty, S. ; Friedland, J. ; Grupo de Trabajo en Cisticercosis en Peru | Instituto Nacional de Salud | 2020-12-14T16:10:04ZThe use of L protein coupled magnetic particles for the concentration and purification of immunoglobulin M (mIgM) monoclonal antibodies against Taenia solium was evaluated. Three concentration methods and different elution times were evaluated a[...]
