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Autor Garcia, H.H. |
Documentos disponibles escritos por este autor (26)
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Mejia Maza, A. ; Carmen-Orozco, R.P. ; Carter, E.S. ; Dávila-Villacorta, D.G. ; Castillo, G. ; Morales, J.D. ; Mamani, J. ; Gavidia, C.M. ; Alroy, J. ; Sterling, C.R. ; Gonzalez, A.E. ; Garcia, H.H. ; Woltjer, R.L. ; Verástegui, M.R. ; Gilman, R.H. ; for the Cysticercosis Working Group in Peru | Wiley | 2019-12-06T21:02:57ZNeurocysticercosis is a parasitic brain disease caused by the larval form (Cysticercus cellulosae) of Taenia solium and is the leading cause of preventable epilepsy worldwide. However, the pathophysiology and relation to the wide range of clinic[...]![]()
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Carmen-Orozco, R.P. ; Dávila-Villacorta, D.G. ; Cauna, Y. ; Bernal-Teran, E.G. ; Bitterfeld, L. ; Sutherland, G.L. ; Chile, N. ; Céliz, R.H. ; Ferrufino-Schmidt, M.C. ; Gavidia, C.M. ; Sterling, C.R. ; Garcia, H.H. ; Gilman, R.H. ; Verástegui, M.R. | Wiley | 2019-12-06T21:02:58ZNeurocysticercosis (NCC) is a helminth infection affecting the central nervous system caused by the larval stage (cysticercus) of Taenia solium. Since vascular alteration and blood–brain barrier (BBB) disruption contribute to NCC pathology, it i[...]![]()
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Mukuku, O. ; Sánchez, S.S. ; Bugeme, M. ; Garcia, H.H. | American Society of Tropical Medicine and Hygiene | 2020-12-14T16:10:01ZNeurocysticercosis (NCC) is an infection prevalent in developing countries; however, it is neglected in the Democratic Republic of the Congo (DRC) and in sub-Saharan Africa. Here, we present three different cases seen in a consulting room in Lub[...]![]()
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León-Janampa, N. ; Liendo, R. ; Gilman, R.H. ; Padilla, C. ; Garcia, H.H. ; Gonzales, A. ; Sheen, P. ; Pajuelo, M.J. ; Zimic, M. ; for the Cysticercosis Working Group in Peru | Elsevier | 2019-12-06T21:02:57ZPorcine cysticercosis is an endemic parasitic disease caused by infection with Taenia solium that is found predominantly in developing countries. In order to aid in the development of simple diagnostic approaches, identification and characteriza[...]![]()
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Lescano, A.G. ; Pray, I.W. ; Gonzalez, A.E. ; Gilman, R.H. ; Tsang, V.C.W. ; Gamboa, R. ; Guezala, M.C. ; Aybar, V. ; Rodriguez, S. ; Moulton, L.H. ; Leontsini, E. ; Gonzalvez, G. ; O'Neal, S.E. ; Garcia, H.H. | American Society of Tropical Medicine and Hygiene | 2019-12-06T20:57:48ZThe pork tapeworm, Taenia solium, is among the leading causes of preventable epilepsy in the world and is common in rural areas of developing countries where sanitation is limited and pigs have access to human feces. Prior studies in rural villa[...]![]()
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Toribio, L. ; Romano, M. ; Scott, A.L. ; Gonzales, I. ; Saavedra, H. ; Garcia, H.H. ; Shiff, C. | American Society of Tropical Medicine and Hygiene | 2019-12-06T21:04:40ZNeurocysticercosis (NCC), caused by Taenia solium larvae that reside in the central nervous system, results in serious public health and medical issues in many regions of the world. Current diagnosis of NCC is complex requiring both serology and[...]![]()
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Toribio, L. ; Santivanez, S. ; Scott, A.L. ; Enriquez, R. ; Sedano, C. ; Soto-Becerra, P. ; Garcia, H.H. ; Shiff, C.J. ; for the Cysticercosis Working Group in Peru | Elsevier B.V. | 2020-12-14T16:10:18ZCystic echinococcosis (CE) is a major neglected tropical zoonotic disease caused by the tissue-dwelling larval stage of the cestode parasite Echinococcus granulosus. For individuals suspected of CE, the diagnostic standard is imaging using ultra[...]![]()
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Del Brutto, O.H. ; Arroyo, G. ; Gonzalez, A.E. ; Zambrano, M. ; Garcia, H.H. | Sociedad Ecuatoriana de Neurología, Liga Ecuatoriana Contra la Epilepsia | 2019-02-22T14:54:06ZObjetivo: Evaluar la prevalencia de cisticercosis porcina en la parroquia rural Atahualpa, un poblado donde se ha demostrado endemia de neurocisticercosis humana. Diseño: Para el presente estudio, se colectarán muestras de sangre de aproximadame[...]![]()
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Fernandez, L. ; Gamboa, R. ; Vilchez, P. ; Pray, I. ; Beam, M. ; Garvey, B. ; Spencer, A. ; Atto, R. ; Muro, C. ; Moyano, L.M. ; Garcia, H.H. ; O’Neal, S.E. | American Society of Tropical Medicine and Hygiene | 2019-12-06T20:57:49ZReintroduction of Taenia solium into a region in Peru where it had been eliminated prompted evaluation of the possibility of reintroduction from an urban reservoir of taeniasis. In a cross-sectional study of an adjacent urban area, we found low [...]![]()
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Gomez-Puerta, L. ; Vargas-Calla, A. ; Castillo, Y. ; Lopez-Urbina, M.T. ; Dorny, P. ; Garcia, H.H. ; Gonzalez, A.E. ; O'Neal, S.E. | BMC | 2019-12-06T21:02:58ZBackground: Taenia solium is an important zoonotic parasite that infects humans as definitive host (taeniasis) and pigs as intermediate host (cysticercosis). Serological diagnosis of porcine cysticercosis is limited to antigen detection using EL[...]![]()
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Gomez-Puerta, L.A. ; Garcia, H.H. ; Gonzalez, A.E. ; Cysticercosis Working Group in Peru | Elsevier | 2019-04-25T15:46:34ZBeetles are intermediate hosts for human and animal parasites, and several beetle species have been shown to carry Taenia eggs. An experimental porcine cysticercosis infection model was developed using beetles (Ammophorus rubripes) infected with[...]![]()
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Del Brutto, O.H. ; Costa, A.F. ; Mera, R.M. ; Recalde, B.Y. ; Bustos, J.A. ; Garcia, H.H. | American Society of Tropical Medicine and Hygiene | 2020-12-14T16:06:19ZThe SARS-CoV-2 pandemic is now expanding into the developing world with devastating consequences. Departing from a population-based study in rural Ecuador where all adult individuals (aged 40 years or older) were tested for SARS-CoV-2 IgG and Ig[...]![]()
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Nash, T.E. ; Mahanty, S. ; Loeb, J.A. ; Theodore, W.H. ; Friedman, A. ; Sander, J.W. ; Singh, G. ; Cavalheiro, E. ; Del Brutto, O.H. ; Takayanagui, O.M. ; Fleury, A. ; Verastegui, M. ; Preux, P.-M. ; Montano, S. ; Pretell, E.J. ; White, A.C. ; Gonzales, A.E. ; Gilman, R.H. ; Garcia, H.H. | Wiley | 2019-04-25T15:46:36ZTo the Editors: Carpio and Romo have emphasized the limitations in our understanding of symptomatic seizures and the epileptogenic process that follows in some, but not all, patients with neurocysticercosis. Their letter also highlights a critic[...]![]()
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Vargas-Calla, A. ; Gomez-Puerta, L.A. ; Lopez, M.T. ; Garcia, H.H. ; Gonzalez, A.E. ; for the Cysticercosis Working Group in Peru | Springer Verlag | 2019-12-06T21:02:55ZSeveral studies have been performed to determine specific antigens for the diagnosis of tapeworms. One of these antigens is Tso31, which is used to differentiate Taenia solium and Taenia saginata in human feces. The aim of the present work was t[...]![]()
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Nash, T.E. ; Mahanty, S. ; Loeb, J.A. ; Theodore, W.H. ; Friedman, A. ; Sander, J.W. ; Singh, G. ; Cavalheiro, E. ; Del Brutto, O.H. ; Takayanagui, O.M. ; Fleury, A. ; Verastegui, M. ; Preux, P.-M. ; Montano, S. ; Pretell, E.J. ; White, A.C. Jr. ; Gonzales, A.E. ; Gilman, R.H. ; Garcia, H.H. | Wiley | 2019-04-25T15:46:36ZObjective To develop a better understanding of mechanisms of seizures and long-term epileptogenesis using neurocysticercosis. Methods A workshop was held bringing together experts in epilepsy and epileptogenesis and neurocysticercosis. Results H[...]![]()
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Gomez-Puerta, L.A. ; Gonzalez, A.E. ; Gavidia, C. ; Ayvar, V. ; Garcia, H.H. ; Lopez-Urbina, M.T. | Elsevier | 2019-04-25T15:46:34ZThe efficacy of oxfendazole (OFZ) on Taenia hydatigena metacestodes, also called Cysticercus tenuicollis ( C. tenuicollis), was studied in 648 raising pigs. This study was performed in Tumbes Department in Peru, an endemic area for cysticercosis[...]![]()
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Gonzalez, A.E. ; Codd, E.E. ; Horton, J. ; Garcia, H.H. ; Gilman, R.H. | Taylor & Francis | 2019-12-06T21:02:58ZIntroduction: Oxfendazole (methyl [5-(phenylsulphinyl)-1H benzimidazole-2-yl] carbamate) has a particularly long metabolic half-life in ruminants, and its metabolite fenbendazole also has anthelminthic action. A very limited number of drugs are [...]![]()
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Bustos, J.A. ; Ninaquispe, B.E. ; Rodriguez, S. ; Castillo, Y. ; Yang, S.Y. ; Gilman, R.H. ; Dorny, P. ; Gabriël, S. ; Garcia, H.H. ; Gonzalez, A.E. | American Society of Tropical Medicine and Hygiene | 2019-12-06T21:02:58ZThe pig is the natural intermediate host of Taenia solium, a parasite causing significant burden of disease in both humans and pigs. Porcine cysticercosis is traditionally detected via tongue palpation and slaughterhouse meat inspection, both wi[...]![]()
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Bach, T. ; Galbiati, S. ; Kennedy, J.K. ; Deye, G. ; Nomicos, E.Y.H. ; Codd, E.E. ; Garcia, H.H. ; Horton, J. ; Gilman, R.H. ; Gonzalez, A.E. ; Winokur, P. ; An, G. | American Society for Microbiology | 2020-12-14T16:06:05ZNeurocysticercosis and trichuriasis are difficult-to-treat parasitic infections that affect more than 1.5 billion people worldwide. Oxfendazole, a potent broad-spectrum benzimidazole anthelmintic approved for use in veterinary medicine, has show[...]![]()
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An, G. ; Murry, D.J. ; Gajurel, K. ; Bach, T. ; Deye, G. ; Stebounova, L.V. ; Codd, E.E. ; Horton, J. ; Gonzalez, A.E. ; Garcia, H.H. ; Ince, D. ; Hodgson-Zingman, D. ; Nomicos, E.Y.H. ; Conrad, T. ; Kennedy, J. ; Jones, W. ; Gilman, R.H. ; Winokur, P. | American Society for Microbiology | 2019-12-06T20:57:46ZCysticercosis is a parasitic disease that frequently involves the human central nervous system (CNS), and current treatment options are limited. Oxfendazole, a veterinary medicine belonging to the benzimidazole family of anthelmintic drugs, has [...]![]()
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McCleery, E. ; Allen, S.E. ; Moyano, L.M. ; Gamboa, R. ; Vilchez, P. ; Muro, C. ; Castillo, Y. ; Dorny, P. ; Garcia, H.H. ; O’Neal, S.E. | American Society of Tropical Medicine and Hygiene | 2020-12-14T16:06:33ZSubarachnoid neurocysticercosis (SANCC) is a severe and progressive brain infection with Taenia solium. We performed a pilot study of noninvasive screening for SANCC in two endemic villages in northern Peru using a urine antigen screen followed [...]![]()
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Recombinant protein- and synthetic peptide-based immunoblot test for diagnosis of neurocysticercosis
Noh, J. ; Rodriguez, S. ; Lee, Y.-M. ; Handali, S. ; Gonzalez, A.E. ; Gilman, R.H. ; Tsang, V.C.W. ; Garcia, H.H. ; Wilkins, P.P. | American Society for Microbiology | 2020-06-10T18:12:15ZOne of the most well-characterized tests for diagnosing neurocysticercosis (NCC) is the enzyme-linked immunoelectrotransfer blot (EITB) assay developed at the CDC, which uses lentil lectin-bound glycoproteins (LLGP) extracted from Taenia solium [...]![]()
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Del Brutto, O.H. ; Costa, A.F. ; Mera, R.M. ; Recalde, B.Y. ; Bustos, J.A. ; Garcia, H.H. | Elsevier B.V. | 2020-12-14T16:06:20ZA sudden increase in adult mortality associated with respiratory diseases was noticed in Atahualpa (a rural Ecuadorian village), coinciding with the introduction of SARS-CoV-2 in the region. From a total of 1,852 individuals aged ?18 years, 40 d[...]![]()
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Gonzales, I. ; Miranda, J.J. ; Rodriguez, S. ; Vargas, V. ; Cjuno, A. ; Smeeth, L. ; Gonzalez, A.E. ; Tsang, V.C.W. ; Gilman, R.H. ; Garcia, H.H. | Wiley | 2019-02-22T14:54:30ZObjectives: To examine the prevalence of seizures, epilepsy and seropositivity to cysticercosis in rural villagers (cysticercosis-endemic setting), rural-to-urban migrants into a non-endemic urban shanty town and urban inhabitants of the same no[...]![]()
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Pray, I.W. ; Wakeland, W. ; Pan, W. ; Lambert, W.E. ; Garcia, H.H. ; Gonzalez, A.E. ; O'Neal, S.E. | BioMed Central | 2020-12-14T16:10:05ZBackground: The pork tapeworm, Taenia solium, is a serious public health problem in rural low-resource areas of Latin America, Africa and Asia, where the associated conditions of nuerocysticercosis (NCC) and porcine cysticercosis cause substanti[...]![]()
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Perez, L.A. ; Castillo, Y. ; Espinoza, C. ; Toribio, L.M. ; Santos, Y. ; Martel, K.S. ; Wilkins, P.P. ; Bustos, J.A. ; Garcia, H.H. ; Castro-Sesquen, Y.E. ; Gilman, R.H. ; Gonzalez, A.E. ; Tsang, V.C.W. ; Rodriguez, S. ; Gonzalez, I. ; Saavedra, H. ; Sanchez, S. ; Martinez, M. ; Verastegui, M. ; Zimic, M. ; Santivanez, S. ; Mayta, H. ; Pajuelo, M. ; Arroyo, G. ; Lopez, M.T. ; Gomez, L. ; Vargas, A. ; Gavidia, C.M. ; Moyano, L.M. ; Gamboa, R. ; Muro, C. ; Vichez, P. ; O´neal, S. ; Handali, S. ; Noh, J. ; Nash, T.E. ; Mahanty, S. ; Friedland, J. ; Grupo de Trabajo en Cisticercosis en Peru | Instituto Nacional de Salud | 2020-12-14T16:10:04ZThe use of L protein coupled magnetic particles for the concentration and purification of immunoglobulin M (mIgM) monoclonal antibodies against Taenia solium was evaluated. Three concentration methods and different elution times were evaluated a[...]