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Lee, Gwenyth O. ; Comina, Germán ; Hernández-Córdova, Gustavo ; Naik, Nehal ; Gayoso, Oscar ; Ticona, Eduardo ; Coronel, Jorge ; Evans, Carlton A. ; Zimic, Mirko ; Paz-Soldan, Valerie A. ; Gilman, Robert H. ; Oberhelman, Richard | Public Library of Science | 2020-07-14T00:02:31ZCough is a characteristic symptom of tuberculosis, is the main cause of transmission, and is used to assess treatment response. We aimed to identify the best measure of cough severity and characterize changes during initial tuberculosis therapy.[...]texto impreso
Proaño, Alvaro ; Bui, David P. ; López, José W. ; Vu, Nancy M. ; Bravard, Marjory A. ; Lee, Gwenyth O. ; Tracey, Brian H. ; Xu, Ziyue ; Comina, Germán ; Ticona, Eduardo ; Mollura, Daniel J. ; Friedland, Jon S. ; Moore, David A. J. ; Evans, Carlton A. ; Caligiuri, Philip ; Gilman, Robert H. | Elsevier | 2018-11-30T03:10:43ZBACKGROUND: Cough frequency, and its duration, is a biomarker that can be used in low-resource settings without the need of laboratory culture and has been associated with transmission and treatment response. Radiologic characteristics associate[...]texto impreso
Proaño, Alvaro ; Bravard, Marjory A. ; López, José W. ; Lee, Gwenyth O. ; Bui, David ; Datta, Sumona ; Comina, Germán ; Zimic, Mirko ; Coronel, Jorge ; Caviedes, Luz ; Cabrera, Jose L. ; Salas, Antonio ; Ticona, Eduardo ; Vu, Nancy M. ; Kirwan, Daniela E. ; Loader, Maria-Cristina I. ; Friedland, Jon S. ; Moore, David A. J. ; Evans, Carlton A. ; Tracey, Brian H. ; Gilman, Robert H. | Oxford University Press | 2019-01-25T16:59:37ZBackground: Cough is the major determinant of tuberculosis transmission. Despite this, there is a paucity of information regarding characteristics of cough frequency throughout the day and in response to tuberculosis therapy. Here we evaluate th[...]texto impreso
Rueda, Daniel ; Furukawa, Roberto ; Fuentes, Patricia ; Comina, Germán ; Rey De Castro, Nicolás G. ; Requena, David ; Gilman, Robert H. ; Sheen, Patricia ; Zimic, Mirko | Medknow Publications | 2018-11-30T02:09:28ZIntroduction: Tuberculosis (TB) is a significant cause of morbidity and mortality worldwide. The patient compliance with the long treatment regimens is essential for successful eradication. Pyrazinamide (PZA) shortens these regimens from 9 to 6 [...]texto impreso
Proaño, Alvaro ; Bravard, Marjory A. ; Tracey, Brian H. ; López, José W. ; Comina, Germán ; Zimic, Mirko ; Coronel, Jorge ; Lee, Gwenyth O'Neil ; Caviedes, Luz ; Cabrera, Jose Luis ; Salas, Antonio ; Ticona, Eduardo ; Kirwan, Daniela E. ; Friedland, Jon S. ; Evans, Carlton A. ; Moore, David A. ; Gilman, Robert H. | BMJ Publishing Group | 2019-02-06T14:51:43ZINTRODUCTION: Cough is a key symptom of tuberculosis (TB) as well as the main cause of transmission. However, a recent literature review found that cough frequency (number of coughs per hour) in patients with TB has only been studied once, in 19[...]
