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Siques, P. ; Brito, J. ; Schwedhelm, E. ; Pena, E. ; León-Velarde, F. ; De La Cruz, J.J. ; Böger, R.H. ; Hannemann, J. | Frontiers Media | 2019-12-06T20:57:43ZBackground: Prolonged exposure to altitude-associated chronic hypoxia (CH) may cause high-altitude pulmonary hypertension (HAPH). Chronic intermittent hypobaric hypoxia (CIH) occurs in individuals who commute between sea level and high altitude.[...]texto impreso
Flores, K. ; Siques, P. ; Brito, J. ; Ordenes, S. ; Arriaza, K. ; Pena, E. ; León-Velarde, F. ; López, R. ; López de Pablo, Á.L. ; Arribas, S. | Frontiers Media | 2020-07-14T00:01:10ZBackground: Both chronic hypoxia (CH) and long-term chronic intermittent hypoxia (CIH) exposure lead to right ventricular hypertrophy (RVH). Weight loss is an effective intervention to improve cardiac function and energy metabolism in cardiac hy[...]texto impreso
Pena, E. ; Siques, P. ; Brito, J. ; Arribas, S.M. ; Böger, R. ; Hannemann, J. ; León-Velarde, F. ; González, M.C. ; López, M.R. ; de Pablo, Á.L.L. | MDPI AG | 2020-12-14T16:10:03ZOne of the consequences of high altitude (hypobaric hypoxia) exposure is the development of right ventricular hypertrophy (RVH). One particular type of exposure is long-term chronic intermittent hypobaric hypoxia (CIH); the molecular alterations[...]texto impreso
Obesity, a worldwide epidemic, has become a major health burden because it is usually accompanied by an increased risk for insulin resistance, diabetes, hypertension, cardiovascular diseases, and even some kinds of cancer. It also results in ass[...]texto impreso
Siques, P. ; Brito, J. ; Naveas, N. ; Pulido, R. ; De La Cruz, J.J. ; Mamani, M. ; León-Velarde, F. | Mary Ann Liebert | 2020-06-10T18:11:30ZPlasma and liver lipid profiles in rats exposed to chronic hypobaric hypoxia: Changes in metabolic pathways. High Alt Med Biol 15:388-395, 2014. - Lipid metabolism under chronic hypoxia (CH) has not received equal attention as intermittent hypox[...]
