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Single, R.M. ; Meyer, D. ; Nunes, K. ; Francisco, R.S. ; Hünemeier, T. ; Maiers, M. ; Hurley, C.K. ; Bedoya, G. ; Gallo, C. ; Hurtado, A.M. ; Llop, E. ; Petzl-Erler, M.L. ; Poletti, G. ; Rothhammer, F. ; Tsuneto, L. ; Klitz, W. ; Ruiz-Linares, A. | Public Library of Science | 2020-12-14T16:10:14ZThe American continent was the last to be occupied by modern humans, and native populations bear the marks of recent expansions, bottlenecks, natural selection, and population substructure. Here we investigate how this demographic history has sh[...]texto impreso
Schmid, A.B. ; Adhikari, K. ; Ramirez-Aristeguieta, L.M. ; Chacón-Duque, J.-C. ; Poletti, G. ; Gallo, C. ; Rothhammer, F. ; Bedoya, G. ; Ruiz-Linares, A. ; Bennett, D.L. | BMJ Publishing Group | 2019-12-06T21:02:54ZIntroduction Pain constitutes a major component of the global burden of diseases. Recent studies suggest a strong genetic contribution to pain susceptibility and severity. Whereas most of the available evidence relies on candidate gene associati[...]texto impreso
Adhikari, K. ; Mendoza-Revilla, J. ; Sohail, A. ; Fuentes-Guajardo, M. ; Lampert, J. ; Chacón-Duque, J.C. ; Hurtado, M. ; Villegas, V. ; Granja, V. ; Acuña-Alonzo, V. ; Jaramillo, C. ; Arias, W. ; Lozano, R.B. ; Everardo, P. ; Gomez-Valdés, J. ; Villamil-Ramírez, H. ; Silva De Cerqueira, C.C. ; Hünemeier, T. ; Ramallo, V. ; Schuler-Faccini, L. ; Salzano, F.M. ; González-José, R. ; Bortolini, M.-C. ; Canizales-Quinteros, S. ; Gallo, C. ; Poletti, G. ; Bedoya, G. ; Rothhammer, F. ; Tobin, D.J. ; Fumagalli, M. ; Balding, D. ; Ruiz-Linares, A. | Nature Research | 2019-12-06T21:02:56ZWe report a genome-wide association scan in > 6,000 Latin Americans for pigmentation of skin and eyes. We found eighteen signals of association at twelve genomic regions. These include one novel locus for skin pigmentation (in 10q26) and three n[...]texto impreso
De Cerqueira, C.C.S. ; Hünemeier, T. ; Gomez-Valdés, J. ; Ramallo, V. ; Volasko-Krause, C.D. ; Barbosa, A.A.L. ; Vargas-Pinilla, P. ; Dornelles, R.C. ; Longo, D. ; Rothhammer, F. ; Bedoya, G. ; Canizales-Quinteros, S. ; Acuña-Alonzo, V. ; Gallo, C. ; Poletti, G. ; González-José, R. ; Salzano, F.M. ; Callegari-Jacques, S.M. ; Schuler-Faccini, L. ; Ruiz-Linares, A. ; Bortolini, M.C. | Public Library of Science | 2020-06-10T18:12:17ZThe understanding of the complex genotype-phenotype architecture of human pigmentation has clear implications for the evolutionary history of humans, as well as for medical and forensic practices. Although dozens of genes have previously been as[...]texto impreso
Delgado, M. ; Ramírez, L.M. ; Adhikari, K. ; Fuentes-Guajardo, M. ; Zanolli, C. ; González-José, R. ; Canizales, S. ; Bortolini, M.-C. ; Poletti, G. ; Gallo, C. ; Rothhammer, F. ; Bedoya, G. ; Ruiz-Linares, A. | Wiley | 2019-12-06T20:57:47ZObjectives: To investigate the variation in dental nonmetric traits and to evaluate the utility of this variation for inferring genetic ancestry proportions in a sample of admixed Latin Americans. Materials and Methods: We characterized a sample[...]
