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High altitude natives are reported to have outstanding work capacity in spite of the challenge of oxygen transport and delivery in hypoxia. To evaluate the developmental effect of lifelong exposure to hypoxia on aerobic capacity, VO2peak was me[...]texto impreso
Miranda, J. Jaime ; Bernabé-Ortiz, Antonio ; Diez-Canseco, Francisco ; Malaga, German ; Cárdenas, María K. ; Carrillo-Larco, Rodrigo M. ; Pesantes, M. Amalia ; Araya, Ricardo ; Boggio, Oscar ; Checkley, William ; García, Patricia J. ; Leon-Velarde, Fabiola ; Lescano, Andres G. ; Montori, Victor ; Pan, William ; Rivera-Chira, Maria ; Sacksteder, Katherine ; Smeeth, Liam ; Garcia, Hector H. ; Gilman, Robert H. | Elsevier | 2019-02-06T14:59:06ZThe CRONICAS Centre of Excellence in Chronic Diseases, based at Universidad Peruana Cayetano Heredia, was created in 2009 with support from the U.S. National Heart, Lung, and Blood Institute (NHLBI). The vision of CRONICAS is to build a globally[...]texto impreso
Kiyamu, Melisa ; Leon-Velarde, Fabiola ; Rivera-Chira, Maria ; Elias, Gianpietro ; Brutsaert, Tom D. | Mary Ann Liebert | 2019-02-06T14:52:35ZKiyamu, Melisa, Fabiola Leon-Velarde, Maria Rivera-Chira, Gianpietro Elias, and Tom D. Brutsaert. Developmental effects determine submaximal arterial oxygen saturation in Peruvian Quechua. High Alt Med Biol 16, 138-146, 2015.--Andean high altitu[...]texto impreso
Vizcarra-Escobar, Darwin ; Mendiola-Yamasato, Andrea ; Risco-Rocca, Jorge ; Marinos-Velarde, Alejandro ; Juarez-Belaunde, Alan ; Anculle-Arauco, Victor ; Rivera-Chira, Maria | Elsevier | 2019-02-06T14:53:41ZBACKGROUND: Restless legs syndrome (RLS) and chronic mountain sickness (CMS) share physiological traits. Our objective was to explore a possible association between RLS and CMS. METHODS: We carried a cross-sectional study with male subjects livi[...]texto impreso
Childebayeva, Ainash ; Jones, Tamara R. ; Goodrich, Jaclyn M. ; Leon-Velarde, Fabiola ; Rivera-Chira, Maria ; Kiyamu, Melisa ; Brutsaert, Tom D. ; Dolinoy, Dana C. ; Bigham, Abigail W. | Taylor & Francis | 2019-07-04T17:00:18ZRecent discoveries indicate a genetic basis for high-altitude adaptation among human groups who have resided at high altitude for millennia, including Andeans, Tibetans, and Ethiopians. Yet, genetics alone does not explain the extent of variati[...]texto impreso
Gazal, Steven ; Espinoza, Jose R. ; Austerlitz, Frederic ; Marchant, Dominique ; Macarlupu, Jose Luis ; Rodriguez, Jorge ; Ju-Preciado, Hugo ; Rivera-Chira, Maria ; Hermine, Olivier ; Leon-Velarde, Fabiola ; Villafuerte, Francisco C. ; Richalet, Jean-Paul ; Gouya, Laurent | Frontiers Media | 2019-12-06T20:57:51ZChronic mountain sickness (CMS) is a pathological condition resulting from chronic exposure to high-altitude hypoxia. While its prevalence is high in native Andeans (> 10%), little is known about the genetic architecture of this disease. Here, w[...]texto impreso
Miranda, J. Jaime ; Bernabé-Ortiz, Antonio ; Diez-Canseco, Francisco ; Malaga, German ; Cárdenas, María K. ; Carrillo-Larco, Rodrigo M. ; Lazo-Porras, Maria ; Moscoso-Porras, Miguel ; Pesantes, M. Amalia ; Ponce, Vilarmina ; Araya, Ricardo ; Beran, David ; Busse, Peter ; Boggio, Oscar ; Checkley, William ; García, Patricia J. ; Huicho, Luis ; Leon-Velarde, Fabiola ; Lescano, Andres G. ; Mohr, David-C. ; Pan, William ; Peiris, David ; Perel, Pablo ; Rabadan-Diehl, Cristina ; Rivera-Chira, Maria ; Sacksteder, Katherine ; Smeeth, Liam ; Trujillo, Antonio J. ; Wells, Jonathan C. K. ; Yan, Lijing-L. ; Garcia, Hector H. ; Gilman, Robert H. | BMC | 2019-02-06T14:51:22ZHuman capital requires opportunities to develop and capacity to overcome challenges, together with an enabling environment that fosters critical and disruptive innovation. Exploring such features is necessary to establish the foundation of solid[...]
